Aliasger K. Salem

Rapid localized cell trapping on biodegradable polymers using cell surface derivatization and microfluidic networking.

A comparative study of the antigen-specific immune response induced by co-delivery of CpG ODN and antigen using fusion molecules or biodegradable microparticles.

Potent antigen-specific immune responses stimulated by codelivery of CpG ODN and antigens in degradable microparticles.

Multifunctional nanorods for biomedical applications.

Spatial control over cell attachment by partial solvent entrapment of poly lysine in microfluidic channels.

Conjugation of polyamidoamine dendrimers on biodegradable microparticles for nonviral gene delivery.

Formulating poly(lactide-co-glycolide) particles for plasmid DNA delivery.

Comparative study of poly (lactic-co-glycolic acid)-poly ethyleneimine-plasmid DNA microparticles prepared using double emulsion methods.

Biotinylated biodegradable nanotemplated hydrogel networks for cell interactive applications.

Pulsatile release of biomolecules from polydimethylsiloxane (PDMS) chips with hydrolytically degradable seals.

Characterization of the transgene expression generated by branched and linear polyethylenimine-plasmid DNA nanoparticles in vitro and after intraperitoneal injection in vivo.

Innovative strategies for co-delivering antigens and CpG oligonucleotides.

Effect of crystal size and surface functionalization on the cytotoxicity of silicalite-1 nanoparticles.

Fabrication, characterization and in vitro evaluation of poly(D,L-lactide-co-glycolide) microparticles loaded with polyamidoamine-plasmid DNA dendriplexes for applications in nonviral gene delivery.

Rational design, fabrication, characterization and in vitro testing of biodegradable microparticles that generate targeted and sustained transgene expression in HepG2 liver cells.

Nanoparticle delivery systems in cancer vaccines.

Intracellular release of 17-β estradiol from cationic polyamidoamine dendrimer surface-modified poly (lactic-co-glycolic acid) microparticles improves osteogenic differentiation of human mesenchymal stromal cells.

Immunostimulatory sutures that treat local disease recurrence following primary tumor resection.

Development of an MHC class I L(d)-restricted PSA peptide-loaded tetramer for detection of PSA-specific CD8+ T cells in the mouse.

Chitosan is a surprising negative modulator of cytotoxic CD8+ T cell responses elicited by adenovirus cancer vaccines.

Efficacy of polymeric encapsulated C5a peptidase-based group B streptococcus vaccines in a murine model.

Silicalite nanoparticles that promote transgene expression.

Synthesis and characterization of mannosylated pegylated polyethylenimine as a carrier for siRNA.

Effects of glucocorticoid receptor small interfering RNA delivered using poly lactic-co-glycolic acid microparticles on proliferation and differentiation capabilities of human mesenchymal stromal cells.

Optimized dextran-polyethylenimine conjugates are efficient non-viral vectors with reduced cytotoxicity when used in serum containing environments.

Poly(galactaramidoamine) is an efficient cationic polymeric non-viral vector with low cytotoxicity for transfecting human embryonic kidney (HEK293) and murine macrophage (RAW264.7) cells.

Effect of Combined Locally Delivered Growth Factors and Systemic Sildenafil Citrate on Microrecanalization in Biodegradable Conduit for Vas Deferens Reconstruction.

Synthesis of the first poly(diaminosulfide)s and an investigation of their applications as drug delivery vehicles.

New class of biodegradable polymers formed from reactions of an inorganic functional group.

Biodegradable particles as vaccine delivery systems: size matters.

Characterizing the antitumor response in mice treated with antigen-loaded polyanhydride microparticles.

Antigen-coated poly α-hydroxy acid based microparticles for heterologous prime-boost adenovirus based vaccinations.

Manipulation of Cell Physiology Enables Gene Silencing in Well-differentiated Airway Epithelia.

Proposed mechanisms of action for prostate cancer vaccines.

Prostate cancer vaccines: Update on clinical development.

The combination of a low-dose chemotherapeutic agent, 5-fluorouracil, and an adenoviral tumor vaccine has a synergistic benefit on survival in a tumor model system.

Microparticles prepared from sulfenamide-based polymers.

Glucocorticoid receptor antagonist and siRNA prevent senescence of human bone marrow mesenchymal stromal cells in vitro.

Biodegradable particles as vaccine antigen delivery systems for stimulating cellular immune responses.

Chitosan coating of copper nanoparticles reduces in vitro toxicity and increases inflammation in the lung.

The enhancement of bone regeneration by gene activated matrix encoding for platelet derived growth factor.

Tumor lysate-loaded biodegradable microparticles as cancer vaccines.

Characterization and evaluation of the efficacy of cationic complex mediated plasmid DNA delivery in human embryonic palatal mesenchyme cells.

The absence of CpG in plasmid DNA-chitosan polyplexes enhances transfection efficiencies and reduces inflammatory responses in murine lungs.

Mechanical properties of murine and porcine ocular tissues in compression.

Production of antigen-loaded biodegradable nanoparticles and uptake by dendritic cells.

Applying biodegradable particles to enhance cancer vaccine efficacy.

Development of a poly (lactic-co-glycolic acid) particle vaccine to protect against house dust mite induced allergy.

A therapeutic microparticle-based tumor lysate vaccine reduces spontaneous metastases in murine breast cancer.

Incorporation of copper into chitosan scaffolds promotes bone regeneration in rat calvarial defects.

Exploiting the tumor phenotype using biodegradable submicron carriers of chemotherapeutic drugs.

Biodegradable microparticles loaded with doxorubicin and CpG ODN for in situ immunization against cancer.

Mitochondria-targeting particles.

Nanoparticles in vaccine delivery.

Three steps to breaking immune tolerance to lymphoma: a microparticle approach.

A Pilot Study Evaluating Combinatorial and Simultaneous Delivery of Polyethylenimine-Plasmid DNA Complexes Encoding for VEGF and PDGF for Bone Regeneration in Calvarial Bone Defects.

Combination of Nanoparticle-Delivered siRNA for Astrocyte Elevated Gene-1 (AEG-1) and All-trans Retinoic Acid (ATRA): An Effective Therapeutic Strategy for Hepatocellular Carcinoma (HCC).

3D Printing of Scaffolds for Tissue Regeneration Applications.

Nanoplex-Mediated Codelivery of Fibroblast Growth Factor and Bone Morphogenetic Protein Genes Promotes Osteogenesis in Human Adipocyte-Derived Mesenchymal Stem Cells.

Correlating intracellular nonviral polyplex localization with transfection efficiency using high-content screening.

Nano-enabled delivery of diverse payloads across complex biological barriers.

Diaminosulfide based polymer microparticles as cancer vaccine delivery systems.

Cytotoxicity of HBD3 for dendritic cells, normal human epidermal keratinocytes, hTERT keratinocytes, and primary oral gingival epithelial keratinocytes in cell culture conditions.

Chemically modified RNA activated matrices enhance bone regeneration.

FGF2 gene activated matrices promote proliferation of bone marrow stromal cells.

Amine modification of nonporous silica nanoparticles reduces inflammatory response following intratracheal instillation in murine lungs.

Differentiation of Induced Pluripotent Stem Cells to Neural Retinal Precursor Cells on Porous Poly-Lactic-co-Glycolic Acid Scaffolds.

Long-term release of a thiobenzamide from a backbone functionalized poly(lactic acid).

Development and Evaluation of Biodegradable Particles Coloaded With Antigen and the Toll-Like Receptor Agonist, Pentaerythritol Lipid A, as a Cancer Vaccine.

The oral and craniofacial relevance of chemically modified RNA therapeutics.

Silica Nanoparticle-Generated ROS as a Predictor of Cellular Toxicity: Mechanistic Insights and Safety by Design.

Neuronal Differentiation of Induced Pluripotent Stem Cells on Surfactant Templated Chitosan Hydrogels.

Controlled and Sequential Delivery of Fluorophores from 3D Printed Alginate-PLGA Tubes.

Size-dependent cytotoxicity of copper oxide nanoparticles in lung epithelial cells.

T-cell activation is enhanced by targeting IL-10 cytokine production in toll-like receptor-stimulated macrophages.

Assessing the effect of engineered nanomaterials on the environment and human health.

Bone Regeneration Using Gene-Activated Matrices.

Gene-Activated Titanium Surfaces Promote In Vitro Osteogenesis.

Production of Adjuvant-Loaded Biodegradable Particles for Use in Cancer Vaccines.

Effect of sustained PDGF nonviral gene delivery on repair of tooth-supporting bone defects.

Surface engineering tumor cells with adjuvant-loaded particles for use as cancer vaccines.

The effect of polyanhydride chemistry in particle-based cancer vaccines on the magnitude of the anti-tumor immune response.

Regeneration of bone using nanoplex delivery of FGF-2 and BMP-2 genes in diaphyseal long bone radial defects in a diabetic rabbit model.

A Comparative Study of the Bone Regenerative Effect of Chemically Modified RNA Encoding BMP-2 or BMP-9.

HPLC-UV method for simultaneous determination of MK-1775 and AZD-7762 in both acetonitrile-aqueous solution and mouse plasma.

Surface-modified particles loaded with CaMKII inhibitor protect cardiac cells against mitochondrial injury.

A novel role of astrocyte elevated gene-1 (AEG-1) in regulating nonalcoholic steatohepatitis (NASH).

Cationic CaMKII Inhibiting Nanoparticles Prevent Allergic Asthma.

Biomimetic Mineralization of Biomaterials Using Simulated Body Fluids for Bone Tissue Engineering and Regenerative Medicine<sup/>.

Recent Advances in Musculoskeletal Tissue Regeneration.

Antitumor Efficacy and Toxicity of 5-Fluorouracil-Loaded Poly(Lactide Co-glycolide) Pellets.

Fabrication and Use of Poly(d,l-lactide-co-glycolide)-Based Formulations Designed for Modified Release of 5-Fluorouracil.

Synthetically lethal nanoparticles for treatment of endometrial cancer.

Combining ultrasound and intratumoral administration of doxorubicin-loaded microspheres to enhance tumor cell killing.

Targeting mitochondrial responses to intra-articular fracture to prevent posttraumatic osteoarthritis.

Nanoparticle-based CpG-oligonucleotide therapy for treating allergic asthma.

Controlled drug delivery from 3D printed two-photon polymerized poly(ethylene glycol) dimethacrylate devices.

Nanoparticle-Based Delivery of CRISPR/Cas9 Genome-Editing Therapeutics.

Single Dose of a Polyanhydride Particle-Based Vaccine Generates Potent Antigen-Specific Antitumor Immune Responses.

Two-Photon Polymerization as a Tool for Studying 3D Printed Topography-Induced Stem Cell Fate.

A bioactive collagen membrane that enhances bone regeneration.

Tissue Engineering for the Temporomandibular Joint.

Improved growth of pea, lettuce, and radish plants using the slow release of hydrogen sulfide from GYY-4137.

Tunable Properties of Poly-DL-Lactide-Monomethoxypolyethylene Glycol Porous Microparticles for Sustained Release of Polyethylenimine-DNA Polyplexes.

MicroRNA-200c Attenuates Periodontitis by Modulating Proinflammatory and Osteoclastogenic Mediators.

Sustained Release of Hydrogen Sulfide (HS) from Poly(Lactic Acid) Functionalized 4-Hydroxythiobenzamide Microparticles to Protect Against Oxidative Damage.

Bullfrog oil (Rana catesbeiana Shaw) induces apoptosis, in A2058 human melanoma cells by mitochondrial dysfunction triggered by oxidative stress.

3D printing in drug delivery systems.

Pentaerythritol-based lipid A bolsters the antitumor efficacy of a polyanhydride particle-based cancer vaccine.

MTDH/AEG-1 downregulation using pristimerin-loaded nanoparticles inhibits Fanconi anemia proteins and increases sensitivity to platinum-based chemotherapy.

Recent Advances in Polymeric Implants.

Effects of calcium concentration on nonviral gene delivery to bone marrow-derived stem cells.

Sulfasalazine Resolves Joint Stiffness in a Rabbit Model of Arthrofibrosis.

A proof of concept gene-activated titanium surface for oral implantology applications.

Bovine immune response to leptospira antigen in different novel adjuvants and vaccine delivery platforms.

Targeting Cell Contractile Forces: A Novel Minimally Invasive Treatment Strategy for Fibrosis.

An injectable microparticle formulation for the sustained release of the specific MEK inhibitor PD98059: in vitro evaluation and pharmacokinetics.

Application of BMP-2/FGF-2 gene-activated scaffolds for dental pulp capping.

Ubiquinol Supplementation of Donor Tissue Enhances Corneal Endothelial Cell Mitochondrial Respiration.

Emerging local delivery strategies to enhance bone regeneration.

Biotinylated Streptavidin Surface Coating Improves the Efficacy of a PLGA Microparticle-Based Cancer Vaccine.

An Injectable Microparticle Formulation Provides Long-Term Inhibition of Hypothalamic ERK1/2 Activity and Sympathetic Excitation in Rats with Heart Failure.

A Multi-Functional Implant Induces Bone Formation in a Diabetic Model.

Comparison of toxicity of aerosolized engineered nanomaterials using air-liquid interface mono-culture and co-culture models.

Toxicity assessment of metal oxide nanomaterials using screening and murine acute inhalation studies.

immunization of a TLR9 agonist virus-like particle enhances anti-PD1 therapy.

Cyclohepta[]thiophenes as Potential Antiproliferative Agents: Design, Synthesis, , and Anticancer Evaluation.

Mechanical cues protect against silica nanoparticle exposure in SH-SY5Y neuroblastoma.

Nonviral Gene Delivery Embedded in Biomimetically Mineralized Matrices for Bone Tissue Engineering.

Implications of current and future approaches to coronavirus disease 2019 testing.

Effect of bacterial contamination in bile on pancreatic cancer cell survival.

Therapeutic Perspectives on the Modulation of G-Protein Coupled Estrogen Receptor, GPER, Function.

Evolution of drug-eluting biomedical implants for sustained drug delivery.

Skin Penetration Enhancement Strategies Used in the Development of Melanoma Topical Treatments.

Obesity diminishes response to PD-1-based immunotherapies in renal cancer.

The anti-tumor effects of cetuximab in combination with VTX-2337 are T cell dependent.

Combining Doxorubicin-Loaded PEGylated Poly(Lactide-co-glycolide) Nanoparticles with Checkpoint Inhibition Safely Enhances Therapeutic Efficacy in a Melanoma Model.

Mapping the immune environment in clear cell renal carcinoma by single-cell genomics.

Applications of nanotechnology in 3D printed tissue engineering scaffolds.

Encapsulating Polyethyleneimine-DNA Nanoplexes into PEGylated Biodegradable Microparticles Increases Transgene Expression In Vitro and Reduces Inflammatory Responses In Vivo.

Enhancement of Therapies for Glioblastoma (GBM) Using Nanoparticle-based Delivery Systems.

Proteolytic Targeting Chimeras with Specificity for Plasma Membrane and Intracellular Estrogen Receptors.

Targeting oxidative stress with amobarbital to prevent intervertebral disc degeneration: Part I. in vitro and ex vivo studies.

Tissue-engineering the larynx: Effect of decellularization on human laryngeal framework and the cricoarytenoid joint.

Inhibition of BMP9 Induced Bone Formation by Salicylic-acid Polymer Capping.

National Institute for Pharmaceutical Technology & Education (NIPTE) Research and Perspective: Advances in Nanotechnology-Based Drug Delivery.

Gene- and RNAi-activated scaffolds for bone tissue engineering: Current progress and future directions.

Direct and indirect immune effects of CMP-001, a virus-like particle containing a TLR9 agonist.

Solubilized ubiquinol for preserving corneal function.