Justin D. Lathia

Targeting A20 decreases glioma stem cell survival and tumor growth.

c-Myc is required for maintenance of glioma cancer stem cells.

Adhesion- and migration-related side effects of phosphothioated CpG oligodeoxynucleotides.

Targeting interleukin 6 signaling suppresses glioma stem cell survival and tumor growth.

Squelching glioblastoma stem cells by targeting REST for proteasomal degradation.

Integrin alpha 6 regulates glioblastoma stem cells.

Erythropoietin Receptor Signaling Through STAT3 Is Required For Glioma Stem Cell Maintenance.

Seeing is believing: are cancer stem cells the Loch Ness monster of tumor biology?

Chemokine receptor CXCR4 signaling modulates the growth factor-induced cell cycle of self-renewing and multipotent neural progenitor cells.

Nonreceptor tyrosine kinase BMX maintains self-renewal and tumorigenic potential of glioblastoma stem cells by activating STAT3.

Deadly teamwork: neural cancer stem cells and the tumor microenvironment.

Glioma stem cell proliferation and tumor growth are promoted by nitric oxide synthase-2.

Direct in vivo evidence for tumor propagation by glioblastoma cancer stem cells.

Twisted tango: brain tumor neurovascular interactions.

Autocrine VEGF-VEGFR2-Neuropilin-1 signaling promotes glioma stem-like cell viability and tumor growth.

Endothelial expression of TNF receptor-1 generates a proapoptotic signal inhibited by integrin α6β1 in glioblastoma.

Holding on to stemness.

Platelet-derived growth factor receptors differentially inform intertumoral and intratumoral heterogeneity.

Chemokine CXCL12 in neurodegenerative diseases: an SOS signal for stem cell-based repair.

The malignant social network: cell-cell adhesion and communication in cancer stem cells.

Laminin alpha 2 enables glioblastoma stem cell growth.

Multiplex flow cytometry barcoding and antibody arrays identify surface antigen profiles of primary and metastatic colon cancer cell lines.

Growth factor receptors define cancer hierarchies.

Glioblastoma stem cells generate vascular pericytes to support vessel function and tumor growth.

Lyn facilitates glioblastoma cell survival under conditions of nutrient deprivation by promoting autophagy.

Cadherin-11 regulates motility in normal cortical neural precursors and glioblastoma.

Brain tumor initiating cells adapt to restricted nutrition through preferential glucose uptake.

Leptin receptor maintains cancer stem-like properties in triple negative breast cancer cells.

The Lgr5 transgene is expressed specifically in glycinergic amacrine cells in the mouse retina.

miR-218 opposes a critical RTK-HIF pathway in mesenchymal glioblastoma.

High-throughput flow cytometry screening reveals a role for junctional adhesion molecule a as a cancer stem cell maintenance factor.

Decoding the cancer stem cell hypothesis in glioblastoma.

EphA2 promotes infiltrative invasion of glioma stem cells in vivo through cross-talk with Akt and regulates stem cell properties.

Cancer stem cell-specific scavenger receptor CD36 drives glioblastoma progression.

Modeling mayhem: predicting invasion and proliferation kinetics in IDH1 mutant glioblastoma with mathematical models.

Profilin-1 phosphorylation directs angiocrine expression and glioblastoma progression through HIF-1α accumulation.

Role of cysteine-rich 61 protein (CCN1) in macrophage-mediated oncolytic herpes simplex virus clearance.

Molecular targeting of TRF2 suppresses the growth and tumorigenesis of glioblastoma stem cells.

Cancer stem cells: moving past the controversy.

Development of a Sox2 reporter system modeling cellular heterogeneity in glioma.

High-Speed Coherent Raman Fingerprint Imaging of Biological Tissues.

Development of a Fluorescent Reporter System to Delineate Cancer Stem Cells in Triple-Negative Breast Cancer.

Feedback circuitry between miR-218 repression and RTK activation in glioblastoma.

Differential connexin function enhances self-renewal in glioblastoma.

Connexin 43 expression is associated with increased malignancy in prostate cancer cell lines and functions to promote migration.

Cancer stem cells in glioblastoma.

Insulin-mediated signaling promotes proliferation and survival of glioblastoma through Akt activation.

The intersection of cancer, cancer stem cells, and the immune system: therapeutic opportunities.

Coordination of self-renewal in glioblastoma by integration of adhesion and microRNA signaling.

Cx25 contributes to leukemia cell communication and chemosensitivity.

Preferential Iron Trafficking Characterizes Glioblastoma Stem-like Cells.

Pharmacological Targeting of the Histone Chaperone Complex FACT Preferentially Eliminates Glioblastoma Stem Cells and Prolongs Survival in Preclinical Models.

Triggering Receptor Expressed on Myeloid Cells 2 Deficiency Alters Acute Macrophage Distribution and Improves Recovery after Traumatic Brain Injury.

Cisplatin induces stemness in ovarian cancer.

Cancer Stem Cell-Secreted Macrophage Migration Inhibitory Factor Stimulates Myeloid Derived Suppressor Cell Function and Facilitates Glioblastoma Immune Evasion.

Taking a Toll on Self-Renewal: TLR-Mediated Innate Immune Signaling in Stem Cells.

Reporter Systems to Study Cancer Stem Cells.

Direct contact with perivascular tumor cells enhances integrin αvβ3 signaling and migration of endothelial cells.

Regulation of Hepatic Triacylglycerol Metabolism by CGI-58 Does Not Require ATGL Co-activation.

Migrating glioma cells express stem cell markers and give rise to new tumors upon xenografting.

Adhering towards tumorigenicity: altered adhesion mechanisms in glioblastoma cancer stem cells.

Tetraspanin CD9 stabilizes gp130 by preventing its ubiquitin-dependent lysosomal degradation to promote STAT3 activation in glioma stem cells.

Glioblastoma Cancer Stem Cells Evade Innate Immune Suppression of Self-Renewal through Reduced TLR4 Expression.

Isolation, Characterization, and Expansion of Cancer Stem Cells.

Brain Cancer Stem Cells in Adults and Children: Cell Biology and Therapeutic Implications.

Metabolic targeting of EGFRvIII/PDK1 axis in temozolomide resistant glioblastoma.

An update on minding the gap in cancer.

Overview of Cancer Stem Cells and Stemness for Community Oncologists.

RBP4-STRA6 Pathway Drives Cancer Stem Cell Maintenance and Mediates High-Fat Diet-Induced Colon Carcinogenesis.

STAT3 activation by leptin receptor is essential for TNBC stem cell maintenance.

Transferrin receptor-1 and ferritin heavy and light chains in astrocytic brain tumors: Expression and prognostic value.

CD55 regulates self-renewal and cisplatin resistance in endometrioid tumors.

Macropinocytosis of Bevacizumab by Glioblastoma Cells in the Perivascular Niche Affects their Survival.

New Advances and Challenges of Targeting Cancer Stem Cells.

A 4-miRNA signature to predict survival in glioblastomas.

Inhibition of Farnesyltransferase Potentiates NOTCH-Targeted Therapy against Glioblastoma Stem Cells.

Revealing the glioma cancer stem cell interactome, one niche at a time.

Cx26 drives self-renewal in triple-negative breast cancer via interaction with NANOG and focal adhesion kinase.

Females have the survival advantage in glioblastoma.

Outlining involvement of stem cell program in regulation of O6-methylguanine DNA methyltransferase and development of temozolomide resistance in glioblastoma: An Editorial Highlight for 'Transcriptional control of O -methylguanine DNA methyltransferase expression and temozolomide resistance in glioblastoma' on page 780.

Therapeutic Injury and Tumor Regrowth: Tumor Resection and Radiation Establish the Recurrent Glioblastoma Microenvironment.

Sex-specific glioma genome-wide association study identifies new risk locus at 3p21.31 in females, and finds sex-differences in risk at 8q24.21.

An anatomic transcriptional atlas of human glioblastoma.

Five-Part Pentameric Nanocomplex Shows Improved Efficacy of Doxorubicin in CD44+ Cancer Cells.

Comparing and Contrasting the Effects of Condensin II Subunit dCAP-D3 Overexpression and Depletion .

Sex-specific gene and pathway modeling of inherited glioma risk.

Homophilic CD44 Interactions Mediate Tumor Cell Aggregation and Polyclonal Metastasis in Patient-Derived Breast Cancer Models.

Global immune fingerprinting in glioblastoma patient peripheral blood reveals immune-suppression signatures associated with prognosis.

Targeting Cancer Stemness in the Clinic: From Hype to Hope.

Sex differences in GBM revealed by analysis of patient imaging, transcriptome, and survival data.

High-Throughput Automated Single-Cell Imaging Analysis Reveals Dynamics of Glioblastoma Stem Cell Population During State Transition.

Drak, Drak, Goose: A New Signaling Axis in Glioblastoma.

Development of a Cx46 Targeting Strategy for Cancer Stem Cells.

IL-11 drives postsurgical hepatocellular carcinoma recurrence.

ADAMDEC1 Maintains a Growth Factor Signaling Loop in Cancer Stem Cells.

The dystroglycan receptor maintains glioma stem cells in the vascular niche.

Metronomic capecitabine as an immune modulator in glioblastoma patients reduces myeloid-derived suppressor cells.

Thy-1 predicts poor prognosis and is associated with self-renewal in ovarian cancer.

Phosphorylation of the histone demethylase KDM5B and regulation of the phenotype of triple negative breast cancer.

ADAMDEC1 and FGF2/FGFR1 signaling constitute a positive feedback loop to maintain GBM cancer stem cells.

Optimising gene editing for cancer therapy.

Identifying conserved molecular targets required for cell migration of glioblastoma cancer stem cells.

FGF2: a novel druggable target for glioblastoma?

MBOAT7-driven phosphatidylinositol remodeling promotes the progression of clear cell renal carcinoma.

Myeloid-Derived Suppressor Cell Subsets Drive Glioblastoma Growth in a Sex-Specific Manner.

Sex Differences in Cancer Incidence and Survival: A Pan-Cancer Analysis.

Release the ballast: Glioblastoma rises above radiation therapy by exporting miR-603 in extracellular vesicles to become treatment-resistant.

JAM-A functions as a female microglial tumor suppressor in glioblastoma.

Glioblastoma Myeloid-Derived Suppressor Cell Subsets Express Differential Macrophage Migration Inhibitory Factor Receptor Profiles That Can Be Targeted to Reduce Immune Suppression.

Sexually dimorphic impact of the iron-regulating gene, , on survival in glioblastoma.

Junctional Adhesion Molecules in Cancer: A Paradigm for the Diverse Functions of Cell-Cell Interactions in Tumor Progression.

SATB2 drives glioblastoma growth by recruiting CBP to promote FOXM1 expression in glioma stem cells.

Hepatobiliary malignancies have distinct peripheral myeloid-derived suppressor cell signatures and tumor myeloid cell profiles.

The evolution of the cancer stem cell state in glioblastoma: emerging insights into the next generation of functional interactions.

High-Dimensional Analysis of Circulating and Tissue-Derived Myeloid-Derived Suppressor Cells from Patients with Glioblastoma.

Connexins in Cancer: Jekyll or Hyde?

Asymmetric cell division promotes therapeutic resistance in glioblastoma stem cells.

Small-Molecule HSP27 Inhibitor Abolishes Androgen Receptors in Glioblastoma.

Preclinical Modeling of Surgery and Steroid Therapy for Glioblastoma Reveals Changes in Immunophenotype that are Associated with Tumor Growth and Outcome.

Comprehensive characterization of protein-protein interactions perturbed by disease mutations.

Cancer cell heterogeneity & plasticity in glioblastoma and brain tumors.

A circuitous route to GBM stem cell signalling.

Go, cancer stem cell, go! CSCs overcome myelin inhibition to move within white matter pathways.

Fountain of chaos: cerebrospinal fluid enhancement of cancer stem cells in glioblastoma.

Sex Differences in Glioblastoma Immunotherapy Response.

Altered lipid metabolism marks glioblastoma stem and non-stem cells in separate tumor niches.

Cancer stem cell-immune cell crosstalk in tumour progression.

Severe consequences of a high-lipid diet include hydrogen sulfide dysfunction and enhanced aggression in glioblastoma.

Neutralizing shapeshifting pericytes enhances glioblastoma therapeutic efficacy.

Multimodal single-cell omics analysis identifies epithelium-immune cell interactions and immune vulnerability associated with sex differences in COVID-19.

Bazedoxifene inhibits sustained STAT3 activation and increases survival in GBM.

Importance of the intersection of age and sex to understand variation in incidence and survival for primary malignant gliomas.

The Translocator Protein () Genetic Polymorphism A147T Is Associated with Worse Survival in Male Glioblastoma Patients.

Hydrogen sulfide operates as a glioblastoma suppressor and is lost under high fat diet.

All damage is not created equal: unraveling the complexity of sex chromosomes and hormones in the DNA damage response.