Soichiro Yamada

Pairwise assembly determines the intrinsic potential for self-organization and mechanical properties of keratin filaments.

The mechanical properties of simple epithelial keratins 8 and 18: discriminating between interfacial and bulk elasticities.

Self-organization of an acentrosomal microtubule network at the basal cortex of polarized epithelial cells.

Deconstructing the cadherin-catenin-actin complex.

Alpha-catenin is a molecular switch that binds E-cadherin-beta-catenin and regulates actin-filament assembly.

Interaction of cadherin with the actin cytoskeleton.

Synapses: sites of cell recognition, adhesion, and functional specification.

Localized zones of Rho and Rac activities drive initiation and expansion of epithelial cell-cell adhesion.

Biochemical and structural analysis of alpha-catenin in cell-cell contacts.

Myosin IIA dependent retrograde flow drives 3D cell migration.

Zyxin-mediated actin assembly is required for efficient wound closure.

Single-cell adhesion tests against functionalized microspheres arrayed on AFM cantilevers confirm heterophilic E- and N-cadherin binding.

The LIM domain of zyxin is sufficient for force-induced accumulation of zyxin during cell migration.

Myosin II activity dependent and independent vinculin recruitment to the sites of E-cadherin-mediated cell-cell adhesion.