Marilyn N. Martinez

A mechanistic approach to understanding the factors affecting drug absorption: a review of fundamentals.

AAPS/RAPS/CAPRA collaborative program: exploring the challenges of drug regulation in a global environment: clinical concerns.

Factors influencing the gastric residence of dosage forms in dogs.

Breakout session summary from AAPS/CRS joint workshop on critical variables in the in vitro and in vivo performance of parenteral sustained release products.

Terminology challenges: defining modified release dosage forms in veterinary medicine.

Dosing regimen matters: the importance of early intervention and rapid attainment of the pharmacokinetic/pharmacodynamic target.

The scientific basis for establishing solubility criteria for veterinary species.

Drug solubility classification in the dog.

Drug solubility classification in the bovine.

Challenges in exploring the cytochrome P450 system as a source of variation in canine drug pharmacokinetics.

Demonstrating comparative in vitro bioequivalence for animal drug products through chemistry and manufacturing controls and physicochemical characterization: a proposal.

Canine gastrointestinal physiology: Breeds variations that can influence drug absorption.

Use of Modeling and Simulation Tools for Understanding the Impact of Formulation on the Absorption of a Low Solubility Compound: Ciprofloxacin.

Erratum to: Use of Modeling and Simulation Tools for Understanding the Impact of Formulation on the Absorption of a Low Solubility Compound: Ciprofloxacin.

Examining the Use of a Mechanistic Model to Generate an In Vivo/In Vitro Correlation: Journey Through a Thought Process.

Optimizing Clinical Drug Product Performance: Applying Biopharmaceutics Risk Assessment Roadmap (BioRAM) and the BioRAM Scoring Grid.

When Is It Important to Measure Unbound Drug in Evaluating Nanomedicine Pharmacokinetics?

Exploring Canine-Human Differences in Product Performance. Part II: Use of Modeling and Simulation to Explore the Impact of Formulation on Ciprofloxacin In Vivo Absorption and Dissolution in Dogs.

What Does It "Mean"? A Review of Interpreting and Calculating Different Types of Means and Standard Deviations.

Proposed method for estimating clinical cut-off (CO) values: An attempt to address challenges encountered when setting clinical breakpoints for veterinary antimicrobial agents.

Formulation characteristics and in vitro release testing of cyclosporine ophthalmic ointments.

Population variability in animal health: Influence on dose-exposure-response relationships: Part II: Modelling and simulation.

Population variability in animal health: Influence on dose-exposure-response relationships: Part I: Drug metabolism and transporter systems.

A Simple Approach for Comparing the In Vitro Dissolution Profiles of Highly Variable Drug Products: a Proposal.

Questions associated with the development of novel drugs intended for the treatment of bacterial infections in veterinary species.

Danazol oral absorption modelling in the fasted dog: An example of mechanistic understanding of formulation effects on drug pharmacokinetics.

Eukaryotic cell culture media affect macrolide minimum inhibitory concentrations but not resistance interpretation for foodborne pathogens.

Reconciling Human-Canine Differences in Oral Bioavailability: Looking beyond the Biopharmaceutics Classification System.

Expert Discussion of the Role of Rate Constant Versus Clearance Approaches to Define Drug Pharmacokinetics: Theoretical and Clinical Considerations.

The Impact of Infection and Inflammation on Drug Metabolism, Active Transport, and Systemic Drug Concentrations in Veterinary Species.

An introduction to the JVPT special issue on antimicrobial drugs.

Evaluation of partial area under the curve in bioequivalence studies using destructive sampling design.

Comparison of Canine and Human Physiological Factors: Understanding Interspecies Differences that Impact Drug Pharmacokinetics.

The publication of studies involving the use of human critically important antimicrobial agents in veterinary species.