Alan L. Schwartz

The ubiquitin-proteasome pathway: the complexity and myriad functions of proteins death.

Basal and human papillomavirus E6 oncoprotein-induced degradation of Myc proteins by the ubiquitin pathway.

Structural motifs involved in ubiquitin-mediated processing of the NF-kappaB precursor p105: roles of the glycine-rich region and a downstream ubiquitination domain.

SCF(beta)(-TrCP) ubiquitin ligase-mediated processing of NF-kappaB p105 requires phosphorylation of its C-terminus by IkappaB kinase.

Receptor-associated protein facilitates proper folding and maturation of the low-density lipoprotein receptor and its class 2 mutants.

Low density lipoprotein (LDL) receptor-related protein 1B impairs urokinase receptor regeneration on the cell surface and inhibits cell migration.

Proteasome regulates the delivery of LDL receptor-related protein into the degradation pathway.

Determinants of nuclear and cytoplasmic ubiquitin-mediated degradation of MyoD.

Cellular catabolism of lipid poor apolipoprotein E via cell surface LDL receptor-related protein.

Degradation of the LDL receptor class 2 mutants is mediated by a proteasome-dependent pathway.

Ubiquitin-Proteasome-mediated degradation of Id1 is modulated by MyoD.

LRP6 expression promotes cancer cell proliferation and tumorigenesis by altering beta-catenin subcellular distribution.

Independent and cooperative roles of N-glycans and molecular chaperones in the folding and disulfide bond formation of the low-density lipoprotein (LDL) receptor-related protein.

Ubiquitin-proteasome-mediated degradation, intracellular localization, and protein synthesis of MyoD and Id1 during muscle differentiation.

E12 and E47 modulate cellular localization and proteasome-mediated degradation of MyoD and Id1.

Slow endocytosis of the LDL receptor-related protein 1B: implications for a novel cytoplasmic tail conformation.

In vivo interactions of MyoD, Id1, and E2A proteins determined by acceptor photobleaching fluorescence resonance energy transfer.

Glucocorticoids differentially regulate degradation of MyoD and Id1 by N-terminal ubiquitination to promote muscle protein catabolism.

Targeting proteins for destruction by the ubiquitin system: implications for human pathobiology.

Low-density lipoprotein receptor-related protein 1 promotes cancer cell migration and invasion by inducing the expression of matrix metalloproteinases 2 and 9.

Ubiquitin proteasome-dependent degradation of the transcriptional coactivator PGC-1{alpha} via the N-terminal pathway.

The Future of Children's Health in the Genomic Era.

American Pediatric Society 2014 presidential address: the thrill of discovery (and other foundations of biomedical research).

Isoform-specific SCF(Fbw7) ubiquitination mediates differential regulation of PGC-1α.

RNF4-Dependent Oncogene Activation by Protein Stabilization.

Physician-Scientist Career Awards and a Dilemma: National Institute of Child Health and Human Development K Awards-Individual, Institutional, or National?

RNA-Seq identifies genes whose proteins are transformative in the differentiation of cytotrophoblast to syncytiotrophoblast, in human primary villous and BeWo trophoblasts.

Noninvasive high-resolution electromyometrial imaging of uterine contractions in a translational sheep model.

Accuracy of electromyometrial imaging of uterine contractions in clinical environment.

Electromyometrial imaging dataset of electromyograms and isochrone maps under deformation/electrical noise contaminations.

Addressing Gaps in Pediatric Scientist Development: The Department Chair View of 2 AMSPDC-Sponsored Programs.

RNA-Seq identifies genes whose proteins are upregulated during syncytia development in murine C2C12 myoblasts and human BeWo trophoblasts.

Analysis of Electrophysiological Activation of the Uterus During Human Labor Contractions.

Noninvasive electromyometrial imaging of human uterine maturation during term labor.