Department of Pediatrics
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The ubiquitin-proteasome pathway: the complexity and myriad functions of proteins death.
Proceedings of the National Academy of Sciences of the United States of America Mar, 1998 | Pubmed ID: 9501156
Basal and human papillomavirus E6 oncoprotein-induced degradation of Myc proteins by the ubiquitin pathway.
Proceedings of the National Academy of Sciences of the United States of America Jul, 1998 | Pubmed ID: 9653139
Structural motifs involved in ubiquitin-mediated processing of the NF-kappaB precursor p105: roles of the glycine-rich region and a downstream ubiquitination domain.
Molecular and cellular biology May, 1999 | Pubmed ID: 10207090
SCF(beta)(-TrCP) ubiquitin ligase-mediated processing of NF-kappaB p105 requires phosphorylation of its C-terminus by IkappaB kinase.
The EMBO journal Jun, 2000 | Pubmed ID: 10835356
Receptor-associated protein facilitates proper folding and maturation of the low-density lipoprotein receptor and its class 2 mutants.
Biochemistry Apr, 2002 | Pubmed ID: 11939787
Low density lipoprotein (LDL) receptor-related protein 1B impairs urokinase receptor regeneration on the cell surface and inhibits cell migration.
The Journal of biological chemistry Nov, 2002 | Pubmed ID: 12194987
Proteasome regulates the delivery of LDL receptor-related protein into the degradation pathway.
Molecular biology of the cell Sep, 2002 | Pubmed ID: 12221136
Determinants of nuclear and cytoplasmic ubiquitin-mediated degradation of MyoD.
The Journal of biological chemistry Jan, 2003 | Pubmed ID: 12397066
Cellular catabolism of lipid poor apolipoprotein E via cell surface LDL receptor-related protein.
Journal of biochemistry Nov, 2002 | Pubmed ID: 12417024
Degradation of the LDL receptor class 2 mutants is mediated by a proteasome-dependent pathway.
Journal of lipid research Jun, 2004 | Pubmed ID: 14993243
Ubiquitin-Proteasome-mediated degradation of Id1 is modulated by MyoD.
The Journal of biological chemistry Jul, 2004 | Pubmed ID: 15163661
LRP6 expression promotes cancer cell proliferation and tumorigenesis by altering beta-catenin subcellular distribution.
Oncogene Dec, 2004 | Pubmed ID: 15516984
Independent and cooperative roles of N-glycans and molecular chaperones in the folding and disulfide bond formation of the low-density lipoprotein (LDL) receptor-related protein.
Biochemistry Apr, 2005 | Pubmed ID: 15823038
Ubiquitin-proteasome-mediated degradation, intracellular localization, and protein synthesis of MyoD and Id1 during muscle differentiation.
The Journal of biological chemistry Jul, 2005 | Pubmed ID: 15888449
E12 and E47 modulate cellular localization and proteasome-mediated degradation of MyoD and Id1.
Oncogene Sep, 2005 | Pubmed ID: 16007194
Slow endocytosis of the LDL receptor-related protein 1B: implications for a novel cytoplasmic tail conformation.
Experimental cell research Sep, 2007 | Pubmed ID: 17658514
In vivo interactions of MyoD, Id1, and E2A proteins determined by acceptor photobleaching fluorescence resonance energy transfer.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology Jun, 2008 | Pubmed ID: 18198216
Glucocorticoids differentially regulate degradation of MyoD and Id1 by N-terminal ubiquitination to promote muscle protein catabolism.
Proceedings of the National Academy of Sciences of the United States of America Mar, 2008 | Pubmed ID: 18296633
Targeting proteins for destruction by the ubiquitin system: implications for human pathobiology.
Annual review of pharmacology and toxicology , 2009 | Pubmed ID: 18834306
Low-density lipoprotein receptor-related protein 1 promotes cancer cell migration and invasion by inducing the expression of matrix metalloproteinases 2 and 9.
Cancer research Feb, 2009 | Pubmed ID: 19176371
Ubiquitin proteasome-dependent degradation of the transcriptional coactivator PGC-1{alpha} via the N-terminal pathway.
The Journal of biological chemistry Dec, 2010 | Pubmed ID: 20713359
The Future of Children's Health in the Genomic Era.
Rambam Maimonides medical journal Jul, 2011 | Pubmed ID: 23908811
American Pediatric Society 2014 presidential address: the thrill of discovery (and other foundations of biomedical research).
Pediatric research Sep, 2014 | Pubmed ID: 24937547
Isoform-specific SCF(Fbw7) ubiquitination mediates differential regulation of PGC-1α.
Journal of cellular physiology Apr, 2015 | Pubmed ID: 25204433
RNF4-Dependent Oncogene Activation by Protein Stabilization.
Cell reports Sep, 2016 | Pubmed ID: 27653698
Physician-Scientist Career Awards and a Dilemma: National Institute of Child Health and Human Development K Awards-Individual, Institutional, or National?
JAMA pediatrics Mar, 2018 | Pubmed ID: 29340560
RNA-Seq identifies genes whose proteins are transformative in the differentiation of cytotrophoblast to syncytiotrophoblast, in human primary villous and BeWo trophoblasts.
Scientific reports Mar, 2018 | Pubmed ID: 29572450
Noninvasive high-resolution electromyometrial imaging of uterine contractions in a translational sheep model.
Science translational medicine Mar, 2019 | Pubmed ID: 30867320
Accuracy of electromyometrial imaging of uterine contractions in clinical environment.
Computers in biology and medicine Jan, 2020 | Pubmed ID: 31786490
Electromyometrial imaging dataset of electromyograms and isochrone maps under deformation/electrical noise contaminations.
Data in brief Feb, 2020 | Pubmed ID: 31956675
Addressing Gaps in Pediatric Scientist Development: The Department Chair View of 2 AMSPDC-Sponsored Programs.
The Journal of pediatrics Jul, 2020 | Pubmed ID: 32586535
RNA-Seq identifies genes whose proteins are upregulated during syncytia development in murine C2C12 myoblasts and human BeWo trophoblasts.
Physiological reports Jan, 2021 | Pubmed ID: 33403800
Analysis of Electrophysiological Activation of the Uterus During Human Labor Contractions.
JAMA network open Jun, 2022 | Pubmed ID: 35653158
Noninvasive electromyometrial imaging of human uterine maturation during term labor.
Nature communications Mar, 2023 | Pubmed ID: 36918533
Hui Wang*,1,2,3,
Zichao Wen*,2,3,
Wenjie Wu2,3,4,
Zhexian Sun2,3,4,
Qing Wang5,
Alan L. Schwartz6,
Phillip Cuculich7,
Alison G. Cahill8,
George A. Macones8,
Yong Wang2,3,4,5
1Department of Physics, Washington University,
2Center for Reproductive Health Sciences, Washington University School of Medicine,
3Department of Obstetrics and Gynecology, Washington University School of Medicine,
4Department of Biomedical Engineering, Washington University,
5Mallinckrodt Institute of Radiology, Washington University School of Medicine,
6Department of Pediatrics, Washington University School of Medicine,
7Department of Cardiology, Washington University School of Medicine,
8Department of Women's Health, University of Texas at Austin, Dell Medical School
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