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Sickkids Research Institute
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Beta-catenin regulates wound size and mediates the effect of TGF-beta in cutaneous healing.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology Apr, 2006 | Pubmed ID: 16581977
PTHrP regulates growth plate chondrocyte differentiation and proliferation in a Gli3 dependent manner utilizing hedgehog ligand dependent and independent mechanisms.
Developmental biology May, 2007 | Pubmed ID: 17328886
Beta-catenin signaling plays a disparate role in different phases of fracture repair: implications for therapy to improve bone healing.
PLoS medicine Jul, 2007 | Pubmed ID: 17676991
T-lymphocytes enable osteoblast maturation via IL-17F during the early phase of fracture repair.
PloS one , 2012 | Pubmed ID: 22768215
β-Catenin-regulated myeloid cell adhesion and migration determine wound healing.
The Journal of clinical investigation Jun, 2014 | Pubmed ID: 24837430
Mutations Preventing Regulated Exon Skipping in MET Cause Osteofibrous Dysplasia.
American journal of human genetics Dec, 2015 | Pubmed ID: 26637977
Hedgehog inhibits β-catenin activity in synovial joint development and osteoarthritis.
The Journal of clinical investigation May, 2016 | Pubmed ID: 27018594
Inhibition of Dopamine Receptor D4 Impedes Autophagic Flux, Proliferation, and Survival of Glioblastoma Stem Cells.
Cancer cell Jun, 2016 | Pubmed ID: 27300435
Mesenchymal Tumors Can Derive from Ng2/Cspg4-Expressing Pericytes with β-Catenin Modulating the Neoplastic Phenotype.
Cell reports Jul, 2016 | Pubmed ID: 27425618
ASCL1 Reorganizes Chromatin to Direct Neuronal Fate and Suppress Tumorigenicity of Glioblastoma Stem Cells.
Cell stem cell Aug, 2017 | Pubmed ID: 28712938
Fate mapping of human glioblastoma reveals an invariant stem cell hierarchy.
Nature Sep, 2017 | Pubmed ID: 28854171
A Feedforward Mechanism Mediated by Mechanosensitive Ion Channel PIEZO1 and Tissue Mechanics Promotes Glioma Aggression.
Neuron Nov, 2018 | Pubmed ID: 30344046
Aged hind-limb clasping experimental autoimmune encephalomyelitis models aspects of the neurodegenerative process seen in multiple sclerosis.
Proceedings of the National Academy of Sciences of the United States of America Nov, 2019 | Pubmed ID: 31641069
Medulloblastoma Arises from the Persistence of a Rare and Transient Sox2 Granule Neuron Precursor.
Cell reports Apr, 2020 | Pubmed ID: 32294450
Single-cell chromatin accessibility profiling of glioblastoma identifies an invasive cancer stem cell population associated with lower survival.
eLife Jan, 2021 | Pubmed ID: 33427645
PRMT5 inhibition disrupts splicing and stemness in glioblastoma.
Nature communications 02, 2021 | Pubmed ID: 33579912
Peroxisome Proliferator-Activated Receptor-δ Deficiency in Microglia Results in Exacerbated Axonal Injury and Tissue Loss in Experimental Autoimmune Encephalomyelitis.
Frontiers in immunology , 2021 | Pubmed ID: 33732230
Modulation of Neutrophil Function by Recombinant Human IgG1 Fc Hexamer in the Endogenous K/BxN Mouse Model of Rheumatoid Arthritis.
Pharmacology , 2023 | Pubmed ID: 36696888
The Hospital for Sick Children
Carmen C. Ucciferri1,
Annette Gower2,
Nuria Alvarez-Sanchez1,2,
Heather Whetstone3,
Valeria Ramaglia1,
Jennifer L. Gommerman1,
Koroboshka Brand-Arzamendi2,
Raphael Schneider2,4,
Shannon E Dunn1,2,5
1Department of Immunology, University of Toronto,
2, Keenan Research Centre for Biomedical Science of St. Michael’s Hospital,
3Sickkids Research Institute, The Hospital for Sick Children,
4BARLO MS Centre, St. Michael’s Hospital,
5Women’s College Research Institute, Women’s College Hospital
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