studying-effects-inhaled-environmental-pollutants-on-olfactory

Studying the Effects of Inhaled Environmental Pollutants on Olfactory Function in Mice

Olfactory impairment is a significant public health problem and independently predicts the risk of neurodegenerative diseases. Inhaled environmental ...

Qingdao University

A novel big defensin was isolated and characterized from the plasma of Ruditapes philippinesis. It was purified to homogeneity by means of precipitation with (NH(4))(2)SO(4), gel-exclusion chromatography, two kinds of cation-exchange chromatography and named RPD-1. Its relative molecular mass was 24.8 kD by means of SDS-PAGE. By means of ABI437 amino acid sequence analyser, its 11 NH(2)-terminal amino acid sequence is AVPDVAFNAYG. Two databank systems (NCBI and EBI/EMBL) was indexed, no sequence with homology to RPD-1 was found. Furthermore, it exhibited strong inhibition on the growth of Gram-negative and -positive bacteria. Minimal inhibitory concentration (MIC) of RPD-1 against Staphylococcus aureus, Bacillus subtilis, Micrococcus tetragenus, Escherichia coli, Vibrio parahaemolyticus, Vibrio anguillarum was 9.6 mg/L, 76.8 mg/L, 38.4 mg/L, 76.8 mg/L, 19.2 mg/L, 19.2 mg/L respectively.

Haowen Chen

Department of Environmental and Occupational Health,
School of Public Health,
Department of Environmental and Occupational Health, School of Public Health

Qingdao University

Studying the Effects of Inhaled Environmental Pollutants on Olfactory Function in Mice

Haowen Chen

Department of Environmental and Occupational Health,School of Public Health,Department of Environmental and Occupational Health, School of Public Health

Qingdao University

Studying the Effects of Inhaled Environmental Pollutants on Olfactory Function in Mice

Department of Environmental and Occupational Health,
School of Public Health,
Department of Environmental and Occupational Health, School of Public Health