Yatrik M. Shah

Selective estrogen receptor modulator regulated proteins in endometrial cancer cells.

The Src kinase pathway promotes tamoxifen agonist action in Ishikawa endometrial cells through phosphorylation-dependent stabilization of estrogen receptor (alpha) promoter interaction and elevated steroid receptor coactivator 1 activity.

Selenium disrupts estrogen receptor (alpha) signaling and potentiates tamoxifen antagonism in endometrial cancer cells and tamoxifen-resistant breast cancer cells.

Attenuation of estrogen receptor alpha (ERalpha) signaling by selenium in breast cancer cells via downregulation of ERalpha gene expression.

Identification of novel proteins induced by estradiol, 4-hydroxytamoxifen and acolbifene in T47D breast cancer cells.

Expression of peroxisome proliferator-activated receptor-gamma in macrophage suppresses experimentally induced colitis.

Pregnane X receptor activation ameliorates DSS-induced inflammatory bowel disease via inhibition of NF-kappaB target gene expression.

Peroxisome proliferator-activated receptor alpha regulates a microRNA-mediated signaling cascade responsible for hepatocellular proliferation.

Rifaximin is a gut-specific human pregnane X receptor activator.

Pioglitazone increases macrophage apoptosis and plaque necrosis in advanced atherosclerotic lesions of nondiabetic low-density lipoprotein receptor-null mice.

PPARalpha: mechanism of species differences and hepatocarcinogenesis of peroxisome proliferators.

Metabolomics reveals that hepatic stearoyl-CoA desaturase 1 downregulation exacerbates inflammation and acute colitis.

Hepatocyte nuclear factor 4alpha in the intestinal epithelial cells protects against inflammatory bowel disease.

Hypoxia-inducible factor augments experimental colitis through an MIF-dependent inflammatory signaling cascade.

A double transgenic mouse model expressing human pregnane X receptor and cytochrome P450 3A4.

Intestinal hypoxia-inducible transcription factors are essential for iron absorption following iron deficiency.

Serum metabolomics reveals irreversible inhibition of fatty acid beta-oxidation through the suppression of PPARalpha activation as a contributing mechanism of acetaminophen-induced hepatotoxicity.

Control of steroid 21-oic acid synthesis by peroxisome proliferator-activated receptor alpha and role of the hypothalamic-pituitary-adrenal axis.

Therapeutic role of rifaximin in inflammatory bowel disease: clinical implication of human pregnane X receptor activation.

PPARalpha-dependent activation of cell cycle control and DNA repair genes in hepatic nonparenchymal cells.

Hypoxia-inducible factor-2α mediates the adaptive increase of intestinal ferroportin during iron deficiency in mice.

Fibrinogen-γ proteolysis and solubility dynamics during apoptotic mouse liver injury: heparin prevents and treats liver damage.

Intestinal hypoxia-inducible factor-2alpha (HIF-2alpha) is critical for efficient erythropoiesis.

Hypoxia-inducible transcription factor 2α promotes steatohepatitis through augmenting lipid accumulation, inflammation, and fibrosis.

Disruption of hypoxia-inducible factor 1 in adipocytes improves insulin sensitivity and decreases adiposity in high-fat diet-fed mice.

Disruption of endothelial peroxisome proliferator-activated receptor γ accelerates diet-induced atherogenesis in LDL receptor-null mice.

The role of peroxisome proliferator-activated receptors in carcinogenesis and chemoprevention.

Peroxisome proliferator-activated receptor alpha induction of uncoupling protein 2 protects against acetaminophen-induced liver toxicity.

Hypoxia-inducible factor-2α activation promotes colorectal cancer progression by dysregulating iron homeostasis.

Decreased hepcidin expression in murine β-thalassemia is associated with suppression of Bmp/Smad signaling.

Pregnane X receptor as a target for treatment of inflammatory bowel disorders.

The hypoxia-inducible factor-C/EBPα axis controls ethanol-mediated hepcidin repression.

Hypoxia-inducible factor-2α is essential in activating the COX2/mPGES-1/PGE2 signaling axis in colon cancer.

Metabolomics identifies an inflammatory cascade involved in dioxin- and diet-induced steatohepatitis.

Analysis of the peroxisome proliferator-activated receptor-β/δ (PPARβ/δ) cistrome reveals novel co-regulatory role of ATF4.

Hypoxia-inducible factor 1α regulates a SOCS3-STAT3-adiponectin signal transduction pathway in adipocytes.