Department of Molecular & Integrative Physiology,
Department of Internal Medicine,
Division of Gastroenterology,
Department of Internal Medicine, Division of Gastroenterology
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Selective estrogen receptor modulator regulated proteins in endometrial cancer cells.
Molecular and cellular endocrinology Apr, 2004 | Pubmed ID: 15149734
The Src kinase pathway promotes tamoxifen agonist action in Ishikawa endometrial cells through phosphorylation-dependent stabilization of estrogen receptor (alpha) promoter interaction and elevated steroid receptor coactivator 1 activity.
Molecular endocrinology (Baltimore, Md.) Mar, 2005 | Pubmed ID: 15528270
Selenium disrupts estrogen receptor (alpha) signaling and potentiates tamoxifen antagonism in endometrial cancer cells and tamoxifen-resistant breast cancer cells.
Molecular cancer therapeutics Aug, 2005 | Pubmed ID: 16093440
Attenuation of estrogen receptor alpha (ERalpha) signaling by selenium in breast cancer cells via downregulation of ERalpha gene expression.
Breast cancer research and treatment Aug, 2005 | Pubmed ID: 16155795
Identification of novel proteins induced by estradiol, 4-hydroxytamoxifen and acolbifene in T47D breast cancer cells.
Steroids Nov, 2006 | Pubmed ID: 16949628
Expression of peroxisome proliferator-activated receptor-gamma in macrophage suppresses experimentally induced colitis.
American journal of physiology. Gastrointestinal and liver physiology Feb, 2007 | Pubmed ID: 17095756
Pregnane X receptor activation ameliorates DSS-induced inflammatory bowel disease via inhibition of NF-kappaB target gene expression.
American journal of physiology. Gastrointestinal and liver physiology Apr, 2007 | Pubmed ID: 17170021
Peroxisome proliferator-activated receptor alpha regulates a microRNA-mediated signaling cascade responsible for hepatocellular proliferation.
Molecular and cellular biology Jun, 2007 | Pubmed ID: 17438130
Rifaximin is a gut-specific human pregnane X receptor activator.
The Journal of pharmacology and experimental therapeutics Jul, 2007 | Pubmed ID: 17442842
Pioglitazone increases macrophage apoptosis and plaque necrosis in advanced atherosclerotic lesions of nondiabetic low-density lipoprotein receptor-null mice.
Circulation Nov, 2007 | Pubmed ID: 17967777
PPARalpha: mechanism of species differences and hepatocarcinogenesis of peroxisome proliferators.
Toxicology Apr, 2008 | Pubmed ID: 18006136
Metabolomics reveals that hepatic stearoyl-CoA desaturase 1 downregulation exacerbates inflammation and acute colitis.
Cell metabolism Feb, 2008 | Pubmed ID: 18249173
Hepatocyte nuclear factor 4alpha in the intestinal epithelial cells protects against inflammatory bowel disease.
Inflammatory bowel diseases Jul, 2008 | Pubmed ID: 18338782
Hypoxia-inducible factor augments experimental colitis through an MIF-dependent inflammatory signaling cascade.
Gastroenterology Jun, 2008 | Pubmed ID: 18439915
A double transgenic mouse model expressing human pregnane X receptor and cytochrome P450 3A4.
Drug metabolism and disposition: the biological fate of chemicals Dec, 2008 | Pubmed ID: 18799805
Intestinal hypoxia-inducible transcription factors are essential for iron absorption following iron deficiency.
Cell metabolism Feb, 2009 | Pubmed ID: 19147412
Serum metabolomics reveals irreversible inhibition of fatty acid beta-oxidation through the suppression of PPARalpha activation as a contributing mechanism of acetaminophen-induced hepatotoxicity.
Chemical research in toxicology Apr, 2009 | Pubmed ID: 19256530
Control of steroid 21-oic acid synthesis by peroxisome proliferator-activated receptor alpha and role of the hypothalamic-pituitary-adrenal axis.
The Journal of biological chemistry Mar, 2010 | Pubmed ID: 20032461
Therapeutic role of rifaximin in inflammatory bowel disease: clinical implication of human pregnane X receptor activation.
The Journal of pharmacology and experimental therapeutics Oct, 2010 | Pubmed ID: 20627999
PPARalpha-dependent activation of cell cycle control and DNA repair genes in hepatic nonparenchymal cells.
Toxicological sciences : an official journal of the Society of Toxicology Dec, 2010 | Pubmed ID: 20813756
Hypoxia-inducible factor-2α mediates the adaptive increase of intestinal ferroportin during iron deficiency in mice.
Gastroenterology Jun, 2011 | Pubmed ID: 21419768
Fibrinogen-γ proteolysis and solubility dynamics during apoptotic mouse liver injury: heparin prevents and treats liver damage.
Hepatology (Baltimore, Md.) Apr, 2011 | Pubmed ID: 21480334
Intestinal hypoxia-inducible factor-2alpha (HIF-2alpha) is critical for efficient erythropoiesis.
The Journal of biological chemistry Jun, 2011 | Pubmed ID: 21498508
Hypoxia-inducible transcription factor 2α promotes steatohepatitis through augmenting lipid accumulation, inflammation, and fibrosis.
Hepatology (Baltimore, Md.) Aug, 2011 | Pubmed ID: 21538443
Disruption of hypoxia-inducible factor 1 in adipocytes improves insulin sensitivity and decreases adiposity in high-fat diet-fed mice.
Diabetes Oct, 2011 | Pubmed ID: 21873554
Disruption of endothelial peroxisome proliferator-activated receptor γ accelerates diet-induced atherogenesis in LDL receptor-null mice.
Arteriosclerosis, thrombosis, and vascular biology Jan, 2012 | Pubmed ID: 22015658
The role of peroxisome proliferator-activated receptors in carcinogenesis and chemoprevention.
Nature reviews. Cancer Mar, 2012 | Pubmed ID: 22318237
Peroxisome proliferator-activated receptor alpha induction of uncoupling protein 2 protects against acetaminophen-induced liver toxicity.
Hepatology (Baltimore, Md.) Jul, 2012 | Pubmed ID: 22318764
Hypoxia-inducible factor-2α activation promotes colorectal cancer progression by dysregulating iron homeostasis.
Cancer research May, 2012 | Pubmed ID: 22419665
Decreased hepcidin expression in murine β-thalassemia is associated with suppression of Bmp/Smad signaling.
Blood Mar, 2012 | Pubmed ID: 22461476
Pregnane X receptor as a target for treatment of inflammatory bowel disorders.
Trends in pharmacological sciences Jun, 2012 | Pubmed ID: 22609277
The hypoxia-inducible factor-C/EBPα axis controls ethanol-mediated hepcidin repression.
Molecular and cellular biology Oct, 2012 | Pubmed ID: 22869521
Hypoxia-inducible factor-2α is essential in activating the COX2/mPGES-1/PGE2 signaling axis in colon cancer.
Carcinogenesis Jan, 2013 | Pubmed ID: 23042097
Metabolomics identifies an inflammatory cascade involved in dioxin- and diet-induced steatohepatitis.
Cell metabolism Nov, 2012 | Pubmed ID: 23140643
Analysis of the peroxisome proliferator-activated receptor-β/δ (PPARβ/δ) cistrome reveals novel co-regulatory role of ATF4.
BMC genomics , 2012 | Pubmed ID: 23176727
Hypoxia-inducible factor 1α regulates a SOCS3-STAT3-adiponectin signal transduction pathway in adipocytes.
The Journal of biological chemistry Feb, 2013 | Pubmed ID: 23255598