Shunqian Jin

BRCA1 regulates GADD45 through its interactions with the OCT-1 and CAAT motifs.

Caspase-3 mediated cleavage of BRCA1 during UV-induced apoptosis.

ATF3 induction following DNA damage is regulated by distinct signaling pathways and over-expression of ATF3 protein suppresses cells growth.

GADD45-induced cell cycle G2-M arrest associates with altered subcellular distribution of cyclin B1 and is independent of p38 kinase activity.

Gadd45a contributes to p53 stabilization in response to DNA damage.

B23 regulates GADD45a nuclear translocation and contributes to GADD45a-induced cell cycle G2-M arrest.

Gadd45a expression induces Bim dissociation from the cytoskeleton and translocation to mitochondria.

Gadd45a interacts with aurora-A and inhibits its kinase activity.

Ethyl pyruvate, a potentially effective mitigator of damage after total-body irradiation.

BRCA1 interaction of centrosomal protein Nlp is required for successful mitotic progression.

MMR/c-Abl-dependent activation of ING2/p73alpha signaling regulates the cell death response to N-methyl-N'-nitro-N-nitrosoguanidine.

The mismatch repair system modulates curcumin sensitivity through induction of DNA strand breaks and activation of G2-M checkpoint.

Aurora B interaction of centrosomal Nlp regulates cytokinesis.

Cdc2/cyclin B1 regulates centrosomal Nlp proteolysis and subcellular localization.

Gfi1 expressed in bone marrow stromal cells is a novel osteoblast suppressor in patients with multiple myeloma bone disease.

Bile acids induce pancreatic acinar cell injury and pancreatitis by activating calcineurin.

Pancreatic acinar cell NF-κB activation due to bile acid exposure is dependent on calcineurin.