Jonathan W. Aylott

A fluorescent PEBBLE nanosensor for intracellular free zinc.

Fluorescent nano-PEBBLE sensors designed for intracellular glucose imaging.

Optical nanosensors--an enabling technology for intracellular measurements.

A non-invasive analysis method for on-chip spectrophotometric detection using liquid-core waveguiding within a 3D architecture.

Optical calcium sensors: development of a generic method for their introduction to the cell using conjugated cell penetrating peptides.

An optical sensor for reactive oxygen species: encapsulation of functionalised silica nanoparticles into silicate nanoprobes to reduce fluorophore leaching.

Internalisation of polymeric nanosensors in mesenchymal stem cells: analysis by flow cytometry and confocal microscopy.

Protease responsive nanoprobes with tethered fluorogenic peptidyl 3-arylcoumarin substrates.

Facile synthesis of responsive nanoparticles with reversible, tunable and rapid thermal transitions from biocompatible constituents.

A facile method to clickable sensing polymeric nanoparticles.

Using fluorescent pH-sensitive nanosensors to report their intracellular location after Tat-mediated delivery.

Porphyrin-nanosensor conjugates. New tools for the measurement of intracellular response to reactive oxygen species.

Protease sensing with nanoparticle based platforms.

Dual fluorescent labelling of cellulose nanocrystals for pH sensing.

Dual-fluorophore ratiometric pH nanosensor with tuneable pKa and extended dynamic range.

Thermoresponsive polymer colloids for drug delivery and cancer therapy.

Mapping the pharyngeal and intestinal pH of Caenorhabditis elegans and real-time luminal pH oscillations using extended dynamic range pH-sensitive nanosensors.