David R. Walt

Aluminum surface corrosion and the mechanism of inhibitors using pH and metal ion selective imaging fiber bundles.

High-density fiber-optic genosensor microsphere array capable of zeptomole detection limits.

Fabrication of an optoelectrochemical microring array.

Optical imaging fiber-based single live cell arrays: a high-density cell assay platform.

Automatic decoding of sensor types within randomly ordered, high-density optical sensor arrays.

Imaging optical sensor arrays.

The use of optical fiber bundles combined with electrochemistry for chemical imaging.

Enhancing vapor sensor discrimination by mimicking a canine nasal cavity flow environment.

Optical imaging fiber-based live bacterial cell array biosensor.

High-density, microsphere-based fiber optic DNA microarrays.

Fluorescence-based fibre optic arrays: a universal platform for sensing.

Combinatorial decoding: an approach for universal DNA array fabrication.

Spatially resolved electrochemiluminescence on an array of electrode tips.

Information coding in artificial olfaction multisensor arrays.

Reversible ratiometric probe for quantitative DNA measurements.

Living bacterial cell array for genotoxin monitoring.

Optical fiber-based biosensors.

Simultaneously monitoring gene expression kinetics and genetic noise in single cells by optical well arrays.

Array-based binary analysis for bacterial typing.

Chemistry. Miniature analytical methods for medical diagnostics.

Individual cell migration analysis using fiber-optic bundles.

Personalized exposure assessment: promising approaches for human environmental health research.

Detection of Salmonella spp. using microsphere-based, fiber-optic DNA microarrays.

Monitoring "promiscuous" drug effects on single cells of multiple cell types.

Optical fiber-based sensors: application to chemical biology.

Development of a microfluidic platform with an optical imaging microarray capable of attomolar target DNA detection.

Extending the longevity of fluorescence-based sensor arrays using adaptive exposure.

Detecting biological warfare agents.

Fiber-optic microsphere-based arrays for multiplexed biological warfare agent detection.

Digital concentration readout of single enzyme molecules using femtoliter arrays and Poisson statistics.

Microbead chemical switches: an approach to detection of reactive organophosphate chemical warfare agent vapors.

Digital readout of target binding with attomole detection limits via enzyme amplification in femtoliter arrays.

Detecting oxygen consumption in the proximity of Saccharomyces cerevisiae cells using self-assembled fluorescent nanosensors.

Fiber-optic microarray for simultaneous detection of multiple harmful algal bloom species.

Fiber-based single cell analysis of reporter gene expression in yeast two-hybrid systems.

Fiber optic array biosensors.

Microsensor arrays for saliva diagnostics.

Duplexed sandwich immunoassays on a fiber-optic microarray.

Optical-fiber bundles.

Stochastic inhibitor release and binding from single-enzyme molecules.

Multianalyte single-cell analysis with multiple cell lines using a fiber-optic array.

Very high density sensing arrays.

Distinct and long-lived activity states of single enzyme molecules.

Use of colorimetric test strips for monitoring the effect of hemodialysis on salivary nitrite and uric acid in patients with end-stage renal disease: a proof of principle.

Detection of single-molecule DNA hybridization using enzymatic amplification in an array of femtoliter-sized reaction vessels.

Fabrication and optical characterization of imaging fiber-based nanoarrays.

Fiber-optic microsphere-based antibody array for the analysis of inflammatory cytokines in saliva.

DNA detection on ultrahigh-density optical fiber-based nanoarrays.

Mechanistic aspects of horseradish peroxidase elucidated through single-molecule studies.

Multiplexed sandwich immunoassays using electrochemiluminescence imaging resolved at the single bead level.

Infochemistry and infofuses for the chemical storage and transmission of coded information.

Temporally resolved fluorescence spectroscopy of a microarray-based vapor sensing system.

Microsphere-based rolling circle amplification microarray for the detection of DNA and proteins in a single assay.

Design, implementation, and field testing of a portable fluorescence-based vapor sensor.

Chromatically resolved optical microscope (CROMoscope): a grating-based instrument for spectral imaging.

Intelligent medical diagnostics via molecular logic.

Ubiquitous sensors: when will they be here?

Detection and classification of ignitable liquid residues using a fluorescence-based vapor-sensitive microsphere array.

Fibre optic microarrays.

Note: Toward multiple addressable optical trapping.

Single-molecule enzyme-linked immunosorbent assay detects serum proteins at subfemtomolar concentrations.

Multiplexed spectroscopic detections.

Bead-based optical fiber arrays for artificial olfaction.

Visualizing Fluorescence: Using a Homemade Fluorescence "Microscope" to View Latent Fingerprints on Paper.

Lessons learned from the introduction of personalized genotyping into a medical school curriculum.

Single cell time-resolved quorum responses reveal dependence on cell density and configuration.

InfoBiology by printed arrays of microorganism colonies for timed and on-demand release of messages.

Oil-sealed femtoliter fiber-optic arrays for single molecule analysis.

Optical methods for single molecule detection and analysis.

Dynamic microbead arrays for biosensing applications.

Assessing the stochastic intermittency of single quantum dot luminescence for robust quantification of biomolecules.

Multiplexed salivary protein profiling for patients with respiratory diseases using fiber-optic bundles and fluorescent antibody-based microarrays.

Salivary inflammatory mediator profiling and correlation to clinical disease markers in asthma.

An automated integrated platform for rapid and sensitive multiplexed protein profiling using human saliva samples.

Observing single enzyme molecules interconvert between activity states upon heating.

Protein measurements in microwells.

Disease detection by ultrasensitive quantification of microdosed synthetic urinary biomarkers.

Advancing the speed, sensitivity and accuracy of biomolecular detection using multi-length-scale engineering.

Genome-wide SNP-genotyping array to study the evolution of the human pathogen Vibrio vulnificus biotype 3.

Stoichiometry of the α-complementation reaction of Escherichia coli β-galactosidase as revealed through single-molecule studies.

Single-molecule arrays for ultrasensitive detection of host immune response to dengue virus infection.

Salivary diagnostics using a portable point-of-service platform: a review.

Ultrasensitive Detection of Ricin Toxin in Multiple Sample Matrixes Using Single-Domain Antibodies.

Ultra-sensitive protein detection via Single Molecule Arrays towards early stage cancer monitoring.

Correlations of salivary biomarkers with clinical assessments in patients with cystic fibrosis.

Single molecule array (Simoa) assay with optimal antibody pairs for cytokine detection in human serum samples.

Protein Counting in Single Cancer Cells.

Incorporation of Slow Off-Rate Modified Aptamers Reagents in Single Molecule Array Assays for Cytokine Detection with Ultrahigh Sensitivity.

Using Antigen-antibody Binding Kinetic Parameters to Understand Single-Molecule Array Immunoassay Performance.

Personal microbiomes and next-generation sequencing for laboratory-based education.

Single-Molecule Arrays for Protein and Nucleic Acid Analysis.

Using Next-Generation Sequencing to Explore Genetics and Race in the High School Classroom.

Digital direct detection of microRNAs using single molecule arrays.

Parkinson's disease biomarkers: perspective from the NINDS Parkinson's Disease Biomarkers Program.

Long-Term Measurements of Human Inflammatory Cytokines Reveal Complex Baseline Variations between Individuals.

Single Molecule Arrays for ultra-sensitive detection of rat cytokines in serum.

Fiber-optic array using molecularly imprinted microspheres for antibiotic analysis.

Development of a Rapid Salivary Proteomic Platform for Oral Feeding Readiness in the Preterm Newborn.

Bottom-up single-molecule strategy for understanding subunit function of tetrameric β-galactosidase.

Detection of amyloid β oligomers toward early diagnosis of Alzheimer's disease.

Impact of clinical sample handling and processing on ultra-low level measurements of plasma cytokines.

Protein Detection by Counting Molecules.

A rapid triage test for active pulmonary tuberculosis in adult patients with persistent cough.

Evaluation of two commercial and two non-commercial immunoassays for the detection of prior infection to SARS-CoV-2.

Ultra-sensitive Serial Profiling of SARS-CoV-2 Antigens and Antibodies in Plasma to Understand Disease Progression in COVID-19 Patients with Severe Disease.

Ultrasensitive high-resolution profiling of early seroconversion in patients with COVID-19.

Plasma IL-6 changes correlate to PD-1 inhibitor responses in NSCLC.