CNC.IBILI/Center for Innovative Biomedicine and Biotechnology (CIBB)
Artur Paiva is the head of Flow Cytometry Unit from Clinical Pathology Service and Associate Professor in Coimbra Health School. He received his Pharmaceutical degree from Faculty of Pharmacy of the University of Coimbra and his Ph.D. from Faculty of Sciences and Technology of the University of Coimbra, Portugal.
His domains of specialization are in the fields of the diagnosis, prognosis and minimal residual detection in haematological malignancies; primary immunodeficiencies diagnosis; evaluation of cellular immune responses; and immunophenotypic and functional characterization of CD34+ cells and mesenchymal stem cells. He also has expertise in Flow Cytometry.
Artur Paiva has more than 100 published articles and his recent research activities and projects are in the earlier diagnosis of leukemia and healthy aging; in the characterization and identification of tumor infiltrating leukocytes in different types of cancer, and in the evaluation of immunosuppressive function of mesenchymal stem/stromal cells for immunotherapy purposes.
On the mechanisms of the internalization of S4(13)-PV cell-penetrating peptide.
The Biochemical journal Sep, 2005 | Pubmed ID: 15907190
Characterization of human sperm populations using conventional parameters, surface ubiquitination, and apoptotic markers.
Fertility and sterility Mar, 2007 | Pubmed ID: 17118365
Differences in hepatitis C virus (HCV)-specific CD8 T-cell phenotype during pegylated alpha interferon and ribavirin treatment are related to response to antiviral therapy in patients chronically infected with HCV.
Journal of virology Aug, 2008 | Pubmed ID: 18480446
S4(13)-PV cell penetrating peptide and cationic liposomes act synergistically to mediate intracellular delivery of plasmid DNA.
The journal of gene medicine Nov, 2008 | Pubmed ID: 18729238
Not all sperm are equal: functional mitochondria characterize a subpopulation of human sperm with better fertilization potential.
PloS one Mar, 2011 | Pubmed ID: 21448461
Therapeutic implications of an enriched cancer stem-like cell population in a human osteosarcoma cell line.
BMC cancer Apr, 2012 | Pubmed ID: 22475227
Tolerogenic versus inflammatory activity of peripheral blood monocytes and dendritic cells subpopulations in systemic lupus erythematosus.
Clinical & developmental immunology , 2012 | Pubmed ID: 22969819
Haematological changes in elite kayakers during a training season.
Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme Dec, 2012 | Pubmed ID: 22973999
Changes in natural killer cell subpopulations over a winter training season in elite swimmers.
European journal of applied physiology Apr, 2013 | Pubmed ID: 22990626
Anterior positioning of sex chromosomes on the head of human sperm sorted using visible wavelengths.
Systems biology in reproductive medicine Aug, 2013 | Pubmed ID: 23631693
Circulating endothelial progenitor cells as a predictor of response to cardiac resynchronization therapy: the missing piece of the puzzle?
Pacing and clinical electrophysiology : PACE Jun, 2014 | Pubmed ID: 24383551
Low amounts of mitochondrial reactive oxygen species define human sperm quality.
Reproduction (Cambridge, England) Jun, 2014 | Pubmed ID: 24534950
Reduced levels of circulating endothelial progenitor cells in acute myocardial infarction patients with diabetes or pre-diabetes: accompanying the glycemic continuum.
Cardiovascular diabetology Jun, 2014 | Pubmed ID: 24934236
Impact of prior chronic statin therapy and high-intensity statin therapy at discharge on circulating endothelial progenitor cell levels in patients with acute myocardial infarction: a prospective observational study.
European journal of clinical pharmacology Oct, 2014 | Pubmed ID: 25048407
Endothelial progenitor cells in diabetic patients with myocardial infarction - can statins improve their function?
European journal of pharmacology Oct, 2014 | Pubmed ID: 25066111
Epstein-Barr virus infection and clinical outcome in breast cancer patients correlate with immune cell TNF-α/IFN-γ response.
BMC cancer Sep, 2014 | Pubmed ID: 25213133
CD38, CD81 and BAFFR combined expression by transitional B cells distinguishes active from inactive systemic lupus erythematosus.
Clinical and experimental medicine May, 2016 | Pubmed ID: 25894569
Sera from patients with active systemic lupus erythematosus patients enhance the toll-like receptor 4 response in monocyte subsets.
Journal of inflammation (London, England) , 2015 | Pubmed ID: 26038677
Lysophosphatidic acid enhances survival of human CD34(+) cells in ischemic conditions.
Scientific reports Nov, 2015 | Pubmed ID: 26553339
High Antimicrobial Activity and Low Human Cell Cytotoxicity of Core-Shell Magnetic Nanoparticles Functionalized with an Antimicrobial Peptide.
ACS applied materials & interfaces 05, 2016 | Pubmed ID: 27074633
Subset-specific alterations in frequencies and functional signatures of γδ T cells in systemic sclerosis patients.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] Dec, 2016 | Pubmed ID: 27576328
Aberrant p15, p16, p53, and DAPK Gene Methylation in Myelomagenesis: Clinical and Prognostic Implications.
Clinical lymphoma, myeloma & leukemia 12, 2016 | Pubmed ID: 27622827
Lifelong training improves anti-inflammatory environment and maintains the number of regulatory T cells in masters athletes.
European journal of applied physiology Jun, 2017 | Pubmed ID: 28391394
Variation in plasma cytokine concentration during a training season in elite kayakers.
The Journal of sports medicine and physical fitness Oct, 2018 | Pubmed ID: 28480686
Increased frequencies of circulating CXCL10-, CXCL8- and CCL4-producing monocytes and Siglec-3-expressing myeloid dendritic cells in systemic sclerosis patients.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] Feb, 2018 | Pubmed ID: 29127442
Mammospheres of hormonal receptor positive breast cancer diverge to triple-negative phenotype.
Breast (Edinburgh, Scotland) Apr, 2018 | Pubmed ID: 29182983
Effects of lifelong training on senescence and mobilization of T lymphocytes in response to acute exercise.
Exercise immunology review , 2018 | Pubmed ID: 29461967
Characterization of circulating gamma-delta T cells in relapsing vs remission multiple sclerosis.
Journal of neuroimmunology 05, 2018 | Pubmed ID: 29506867
Amniotic membrane extract differentially regulates human peripheral blood T cell subsets, monocyte subpopulations and myeloid dendritic cells.
Cell and tissue research 08, 2018 | Pubmed ID: 29582167
Stroma-derived IL-6, G-CSF and Activin-A mediated dedifferentiation of lung carcinoma cells into cancer stem cells.
Scientific reports 08, 2018 | Pubmed ID: 30069023
Immune-endocrine responses and physical performance of master athletes during the sports season.
Journal of cellular biochemistry Apr, 2019 | Pubmed ID: 30320909
Interferon-beta treated-multiple sclerosis patients exhibit a decreased ratio between immature/transitional B cell subset and plasmablasts.
Journal of neuroimmunology 01, 2019 | Pubmed ID: 30476705
Impact of cardiac resynchronization therapy on circulating IL-17 producing cells in patients with advanced heart failure.
Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing Apr, 2019 | Pubmed ID: 30483979
Endometrial Cancer Spheres Show Cancer Stem Cells Phenotype and Preference for Oxidative Metabolism.
Pathology oncology research : POR Jul, 2019 | Pubmed ID: 30499076
Lipoxidation and cancer immunity.
Redox biology 05, 2019 | Pubmed ID: 30658904
Functional Impairment of Circulating FcεRI Monocytes and Myeloid Dendritic Cells in Hepatocellular Carcinoma and Cholangiocarcinoma Patients.
Cytometry. Part B, Clinical cytometry Nov, 2019 | Pubmed ID: 30828998
Lipidomics in autoimmune diseases with main focus on systemic lupus erythematosus.
Journal of pharmaceutical and biomedical analysis Sep, 2019 | Pubmed ID: 31207360
Functional and Phenotypic Characterization of Tumor-Infiltrating Leukocyte Subsets and Their Contribution to the Pathogenesis of Hepatocellular Carcinoma and Cholangiocarcinoma.
Translational oncology Nov, 2019 | Pubmed ID: 31425839
Immunomodulatory effect of human bone marrow-derived mesenchymal stromal/stem cells on peripheral blood T cells from rheumatoid arthritis patients.
Journal of tissue engineering and regenerative medicine Jan, 2020 | Pubmed ID: 31502378
Alterations in circulating T cell functional subpopulations in interferon-beta treated multiple sclerosis patients: A pilot study.
Journal of neuroimmunology Feb, 2020 | Pubmed ID: 31778850
Complete Multilineage CD4 Expression Defect Associated With Warts Due to an Inherited Homozygous CD4 Gene Mutation.
Frontiers in immunology , 2019 | Pubmed ID: 31781092
Fluorescent probes for the detection of reactive oxygen species in human spermatozoa.
Asian journal of andrology Jan, 2020 | Pubmed ID: 31939350
Tumor Resection Induces Alterations on Serum Phospholipidome of Liver Cancer Patients.
Lipids Feb, 2020 | Pubmed ID: 32045496
Mafalda Laranjo*,1,2,3,4,
Maria João Carvalho*,1,2,3,4,5,6,
Beatriz Serambeque1,2,3,
André Alves2,7,
Carlos Miguel Marto1,2,3,4,8,
Isabel Silva9,
Artur Paiva3,9,10,
Maria Filomena Botelho1,2,3,4,8
1Institute of Biophysics, Faculty of Medicine, University of Coimbra,
2Coimbra Institute for Clinical and Biomedical Research (iCBR), area of Environment Genetics and Oncobiology (CIMAGO), Faculty of Medicine, University of Coimbra,
3CNC.IBILI/Center for Innovative Biomedicine and Biotechnology (CIBB), University of Coimbra,
4, Clinical Academic Center of Coimbra (CACC),
5Universitary Clinic of Gynecology, Faculty of Medicine, University of Coimbra,
6Gynecology A Service, Coimbra Hospital and Universitary Center,
7Institute of Pharmacology & Experimental Therapeutics, Faculty of Medicine, University of Coimbra,
8Institute of Experimental Pathology, Faculty of Medicine, University of Coimbra,
9Cytometry Operational Management Unit, Clinical Pathology Service, Coimbra Hospital and Universitary Center,
10Polytechnic Institute of Coimbra, ESTESC-Coimbra Health School, Laboratory Biomedical Sciences
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