John H. Boyd

Upper airway muscle inflammation and denervation changes in obstructive sleep apnea.

Cardiac ICAM-1 mediates leukocyte-dependent decreased ventricular contractility in endotoxemic mice.

Toll-like receptors differentially regulate CC and CXC chemokines in skeletal muscle via NF-kappaB and calcineurin.

Toll-like receptor stimulation in cardiomyoctes decreases contractility and initiates an NF-kappaB dependent inflammatory response.

Fibrinogen decreases cardiomyocyte contractility through an ICAM-1-dependent mechanism.

S100A8 and S100A9 mediate endotoxin-induced cardiomyocyte dysfunction via the receptor for advanced glycation end products.

Is there a role for sodium bicarbonate in treating lactic acidosis from shock?

Vasopressin decreases sepsis-induced pulmonary inflammation through the V2R.

The role of echocardiography in hemodynamic monitoring.

Low-dose vasopressin infusion results in increased mortality and cardiac dysfunction following ischemia-reperfusion injury in mice.

beta2-Adrenergic receptor gene polymorphism is associated with mortality in septic shock.

Toll-like receptor 4-mediated activation of p38 mitogen-activated protein kinase is a determinant of respiratory virus entry and tropism.

Inhibition of monocyte chemoattractant protein-1 prevents diaphragmatic inflammation and maintains contractile function during endotoxemia.

Fluid resuscitation in septic shock: a positive fluid balance and elevated central venous pressure are associated with increased mortality.

A single nucleotide polymorphism in NF-κB inducing kinase is associated with mortality in septic shock.

Leucyl/cystinyl aminopeptidase gene variants in septic shock.

Association of angiotensin II type 1 receptor-associated protein gene polymorphism with increased mortality in septic shock.

Extracellular heat shock protein 70 induces cardiomyocyte inflammation and contractile dysfunction via TLR2.

Globalization of ejection fraction: the pulmonary artery catheter has been outsourced.

The Toll-like receptor 9 ligand CPG-C attenuates acute inflammatory cardiac dysfunction.

IL17A genetic variation is associated with altered susceptibility to Gram-positive infection and mortality of severe sepsis.

Inflammation in myocardial diseases.

A common polymorphism in the 5' region of the human protein c gene binds USF1.

Normal-range blood lactate concentration in septic shock is prognostic and predictive.

Toll-like receptors and opportunities for new sepsis therapeutics.

AA genotype of IL-8 -251A/T is associated with low PaO(2)/FiO(2) in critically ill patients and with increased IL-8 expression.

One size does not fit all in severe infection: obesity alters outcome, susceptibility, treatment, and inflammatory response.

A multibiomarker-based outcome risk stratification model for adult septic shock*.

Prolonged QTc affects short-term and long-term outcomes in patients with normal left ventricular function undergoing cardiac surgery.

The meta-genome of sepsis: host genetics, pathogens and the acute immune response.

Metagenomics and innate immunity - a unique partnership or a battlefield?

Small acute increases in serum creatinine are associated with decreased long-term survival in the critically ill.

Barriers to the effective treatment of sepsis: antimicrobial agents, sepsis definitions, and host-directed therapies.

Limited echocardiography-guided therapy in subacute shock is associated with change in management and improved outcomes.

Serious adverse events associated with vasopressin and norepinephrine infusion in septic shock.

Long-term (10-year) mortality of younger previously healthy patients with severe sepsis/septic shock is worse than that of patients with nonseptic critical illness and of the general population.

A functional synonymous coding variant in the IL1RN gene is associated with survival in septic shock.

Identification of a nonsynonymous polymorphism in the SVEP1 gene associated with altered clinical outcomes in septic shock.

PCSK9 is a critical regulator of the innate immune response and septic shock outcome.

Once is enough: limited echocardiography in subacute shock.

An Endotoxin Tolerance Signature Predicts Sepsis and Organ Dysfunction at Initial Clinical Presentation.

VPS13D Gene Variant Is Associated with Altered IL-6 Production and Mortality in Septic Shock.