Stephen L. Archer

Role of dynamin-related protein 1 (Drp1)-mediated mitochondrial fission in oxygen sensing and constriction of the ductus arteriosus.

PGC1α-mediated mitofusin-2 deficiency in female rats and humans with pulmonary arterial hypertension.

The role of redox signaling in epigenetics and cardiovascular disease.

Metabolism and bioenergetics in the right ventricle and pulmonary vasculature in pulmonary hypertension.

Cardiac glutaminolysis: a maladaptive cancer metabolism pathway in the right ventricle in pulmonary hypertension.

Atrioventricular heart block and syncope coincident with diagnosis of systemic lupus erythematosus.

Dynamin-related protein 1 (Drp1)-mediated diastolic dysfunction in myocardial ischemia-reperfusion injury: therapeutic benefits of Drp1 inhibition to reduce mitochondrial fission.

SIRT3 deacetylates and activates OPA1 to regulate mitochondrial dynamics during stress.

Relevant issues in the pathology and pathobiology of pulmonary hypertension.

Activation of the EGFR/p38/JNK pathway by mitochondrial-derived hydrogen peroxide contributes to oxygen-induced contraction of ductus arteriosus.

The right ventricle in pulmonary arterial hypertension: disorders of metabolism, angiogenesis and adrenergic signaling in right ventricular failure.

Peripheral blood signature of vasodilator-responsive pulmonary arterial hypertension.

Inhibition of the mitochondrial fission protein dynamin-related protein 1 improves survival in a murine cardiac arrest model.

Mitochondrial dynamics in cardiovascular disease: fission and fusion foretell form and function.

Soluble guanylate cyclase: a new therapeutic target for pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension.

Mitochondrial dynamics in pulmonary arterial hypertension.

Right ventricular adaptation and failure in pulmonary arterial hypertension.

Emerging concepts in the molecular basis of pulmonary arterial hypertension: part I: metabolic plasticity and mitochondrial dynamics in the pulmonary circulation and right ventricle in pulmonary arterial hypertension.

A mitochondrial redox oxygen sensor in the pulmonary vasculature and ductus arteriosus.

Gone fission: an asymptomatic STAT2 mutation elongates mitochondria and causes human disease following viral infection.

Critical Genomic Networks and Vasoreactive Variants in Idiopathic Pulmonary Arterial Hypertension.

Pulmonary hypertension begets pulmonary hypertension: mutually reinforcing roles for haemodynamics, inflammation, and cancer-like phenotypes.

Acquired Mitochondrial Abnormalities, Including Epigenetic Inhibition of Superoxide Dismutase 2, in Pulmonary Hypertension and Cancer: Therapeutic Implications.

Hypoxic Pulmonary Vasoconstriction: From Molecular Mechanisms to Medicine.

MicroRNA-138 and MicroRNA-25 Down-regulate Mitochondrial Calcium Uniporter, Causing the Pulmonary Arterial Hypertension Cancer Phenotype.

The role of Drp1 adaptor proteins MiD49 and MiD51 in mitochondrial fission: implications for human disease.

Executive Summary of the American Heart Association and American Thoracic Society Joint Guidelines for Pediatric Pulmonary Hypertension.

Pulmonary pulse wave transit time is associated with right ventricular-pulmonary artery coupling in pulmonary arterial hypertension.

Ischemia-induced Drp1 and Fis1-mediated mitochondrial fission and right ventricular dysfunction in pulmonary hypertension.

Abnormal angiogenesis in blood outgrowth endothelial cells derived from von Willebrand disease patients.

Colchicine Depolymerizes Microtubules, Increases Junctophilin-2, and Improves Right Ventricular Function in Experimental Pulmonary Arterial Hypertension.

Resistance over compliance describes right ventricular afterload better than resistance-compliance time: a friendly amendment.

Interleukin-6 is independently associated with right ventricular function in pulmonary arterial hypertension.

Models and Molecular Mechanisms of World Health Organization Group 2 to 4 Pulmonary Hypertension.

Pyruvate Kinase and Warburg Metabolism in Pulmonary Arterial Hypertension: Uncoupled Glycolysis and the Cancer-Like Phenotype of Pulmonary Arterial Hypertension.

Disproportionate Right Ventricular Dysfunction and Poor Survival in Group 3 Pulmonary Hypertension.

Epigenetic Dysregulation of the Dynamin-Related Protein 1 Binding Partners MiD49 and MiD51 Increases Mitotic Mitochondrial Fission and Promotes Pulmonary Arterial Hypertension: Mechanistic and Therapeutic Implications.

Increasing Incidence and Prevalence of World Health Organization Groups 1 to 4 Pulmonary Hypertension: A Population-Based Cohort Study in Ontario, Canada.

Pulmonary arterial hypertension: pathogenesis and clinical management.

Standards and Methodological Rigor in Pulmonary Arterial Hypertension Preclinical and Translational Research.

A pro-con debate: current controversies in PAH pathogenesis at the American Thoracic Society International Conference in 2017.

Increased Drp1-Mediated Mitochondrial Fission Promotes Proliferation and Collagen Production by Right Ventricular Fibroblasts in Experimental Pulmonary Arterial Hypertension.

A Step Closer to Understanding How Riociguat Results in Remodelling of the Right Ventricle in Chronic Thromboembolic Pulmonary Hypertension.

Transcriptomic Signature of Right Ventricular Failure in Experimental Pulmonary Arterial Hypertension: Deep Sequencing Demonstrates Mitochondrial, Fibrotic, Inflammatory and Angiogenic Abnormalities.

Survival in pulmonary hypertension due to chronic lung disease: Influence of low diffusion capacity of the lungs for carbon monoxide.