Modified In Vivo Matrix Gel Plug Assay for Angiogenesis StudiesZixian Lu *1,2, Mei Yi *2, Taoli Chen *2, Yue He *2, Xia Fan *2, Hui Chen 2, Yinli Huang 1, Jianlou Niu 1,2, Xiaoqing Yan 1,2
1Pingyang Affiliated Hospital of Wenzhou Medical University, 2School of Pharmaceutical Sciences, Wenzhou Medical University
The method presented here can evaluate the effect of reagents on angiogenesis or vascular permeability in vivo without staining. The method uses dextran-FITC injection via the tail vein to visualize neo-vessels or vascular leakage.
