Creating a Box-Cavity Defect Model in the Cortical Bone of Rat FemoraYiyun Chen 1,2, Jiayi Wu 1,2, Feifei Li 1, Ling Ye 1,2, Haisheng Wang 1
1State Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, 2Department of Endodontics, West China Hospital of Stomatology, Sichuan University
Here, we present a protocol for creating a box-cavity defect in rat femoral diaphysis tissue. This model can assess biomaterial performance under biomechanical stress and explore mechanisms of bone regeneration related to intramembranous osteogenesis.
