Alternative Methods for the Detection of Superoxide Anion Generation in Platelets Dina Vara 1, Sophie Leonard 2, Simon Calaminus 2, Giordano Pula 2
1Medicines and Healthcare Regulatory Agency, South Mimms laboratories, 2Hull York Medical School, University of Hull
The generation of superoxide anion is essential for the stimulation of platelets and, if dysregulated, critical for thrombotic diseases. Here, we present three protocols for the selective detection of superoxide anions and the study of redox-dependent platelet regulation.
