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1 ARTICLES PUBLISHED IN JoVE

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Neuroscience

A Rat Model of Mild Intrauterine Hypoperfusion with Microcoil Stenosis
Masahiro Tsuji 1, Jacques-Olivier Coq 2, Yuko Ogawa 1, Yumi Yamamoto 1, Makiko Ohshima 1
1Department of Regenerative Medicine and Tissue Engineering, National Cerebral and Cardiovascular Center, 2Institut de Neurosciences de la Timone, CNRS, Aix Marseille Université

Mild intrauterine hypoperfusion was produced by artery stenosis with metal microcoils wrapped around the uterine and ovarian arteries in rats at embryonic day 17. This procedure produced prenatal hypoperfusion and intrauterine growth restriction.

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