A Rat Model of Mild Intrauterine Hypoperfusion with Microcoil StenosisMasahiro Tsuji 1, Jacques-Olivier Coq 2, Yuko Ogawa 1, Yumi Yamamoto 1, Makiko Ohshima 1
1Department of Regenerative Medicine and Tissue Engineering, National Cerebral and Cardiovascular Center, 2Institut de Neurosciences de la Timone, CNRS, Aix Marseille Université
Mild intrauterine hypoperfusion was produced by artery stenosis with metal microcoils wrapped around the uterine and ovarian arteries in rats at embryonic day 17. This procedure produced prenatal hypoperfusion and intrauterine growth restriction.
