MatTek In Vitro Life Science Laboratories
2 ARTICLES PUBLISHED IN JoVE
Biology
An In Vitro Skin Irritation Test (SIT) using the EpiDerm Reconstructed Human Epidermal (RHE) Model
Helena Kandárová 1, Patrick Hayden 1, Mitchell Klausner 1, Joseph Kubilus 1, John Sheasgreen 1
1MatTek Corporation
In this video, we demonstrate the EpiDerm Skin Irritation test (EpiDerm SIT) developed and validated for in vitro skin irritation testing of chemicals, including cosmetic and pharmaceutical ingredients.
Bioengineering
Eye Irritation Test (EIT) for Hazard Identification of Eye Irritating Chemicals using Reconstructed Human Cornea-like Epithelial (RhCE) Tissue Model
Yulia Kaluzhny 1, Helena Kandárová 2, Laurence d’Argembeau-Thornton 1, Paul Kearney 1, Mitchell Klausner 1
1MatTek Corporation, 2MatTek In Vitro Life Science Laboratories
We have developed an eye irritation test which utilizes a three dimensional reconstructed human cornea-like epithelial (RhCE) tissue model. The test is able to discriminate between ocular irritant and corrosive materials (GHS Categories 1 and 2 combined) and those that do not require labeling (GHS No Category).
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