In vivo Imaging of Tumor Angiogenesis using Fluorescence Confocal VideomicroscopyVictor Fitoussi 1, Nathalie Faye 1, Foucauld Chamming's 1,2, Olivier Clement 1,2, Charles-Andre Cuenod 1,2, Laure S. Fournier 1,2
1Université Paris Descartes Sorbonne Paris Cité, INSERM UMR-S970, 2Assistance Publique-Hôpitaux de Paris, Hôpital Européen Georges Pompidou, Service de Radiologie
In this paper, we present a method to analyze tumor microvessels in vivo using dynamic contrast-enhanced fluorescence videomicroscopy. Two quantitative parameters were acquired: functional capillary density reflecting the vascularity of the tumor, and index leakage reflecting the leakiness of the endothelial wall.
