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1 ARTICLES PUBLISHED IN JoVE

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Chemistry

Applications of Liquid-Chromatography Tandem Mass Spectrometry in Natural Products Research: Tropane Alkaloids as a Case Study
Maris A. Cinelli 1, Jill Cline 1, Tyler Watson 1
1Department of Chemistry, Northern Michigan University

We present a method for rapid mass spectrometry (MS)/mass spectrometry (MS)-based annotation and classification of tropane alkaloids, useful for both preliminary dereplication of tropane-containing samples and discovery of novel alkaloids for isolation.

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