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Northern Michigan University

1 ARTICLES PUBLISHED IN JoVE

Chemistry

Applications of Liquid-Chromatography Tandem Mass Spectrometry in Natural Products Research: Tropane Alkaloids as a Case Study

Maris A. Cinelli¹, Jill Cline¹, Tyler Watson¹

¹Department of Chemistry, Northern Michigan University

We present a method for rapid mass spectrometry (MS)/mass spectrometry (MS)-based annotation and classification of tropane alkaloids, useful for both preliminary dereplication of tropane-containing samples and discovery of novel alkaloids for isolation.