JoVE Logo
Authors
Contact Us

Sign In

Core - Cell Biology

    Chapter 11

    Control of Gene Expression

    11.1 : Cell Specific Gene Expression01:58

    11.1 : Cell Specific Gene Expression

    Multicellular organisms contain a variety of structurally and functionally distinct cell types, but the DNA in all the cells originated from the same ...

    4.5K views
    11.2 : Regulation of Expression Occurs at Multiple Steps02:24

    11.2 : Regulation of Expression Occurs at Multiple Steps

    Gene expression can be regulated at almost every step from gene to protein. Transcription is the step that is most commonly regulated. This involves the ...

    2.9K views
    11.3 : Cis-regulatory Sequences02:02

    11.3 : Cis-regulatory Sequences

    Cis-regulatory sequences are short fragments of non-coding DNA that are present on the same chromosomes as the genes that they regulate. These fragments ...

    2.9K views
    11.4 : Cooperative Binding of Transcription Regulators02:13

    11.4 : Cooperative Binding of Transcription Regulators

    Transcriptional regulators bind to specific cis-regulatory sequences in the DNA to regulate gene transcription. These cis-regulatory sequences are ...

    2.0K views
    11.5 : Prokaryotic Transcriptional Activators and Repressors01:58

    11.5 : Prokaryotic Transcriptional Activators and Repressors

    The organization of prokaryotic genes in their genome is notably different from that of eukaryotes. Prokaryotic genes are organized, such that the genes ...

    8.2K views
    11.6 : The Eukaryotic Promoter Region02:40

    11.6 : The Eukaryotic Promoter Region

    The eukaryotic promoter region is a segment of DNA located upstream of a gene. It contains an RNA polymerase binding site, a transcription start site, and ...

    2.9K views
    11.7 : Co-activators and Co-repressors02:04

    11.7 : Co-activators and Co-repressors

    Gene transcription is regulated by the synergistic action of several proteins that form a complex at a gene regulatory site. This is observed in ...

    2.2K views
    11.8 : Master Transcription Regulators02:23

    11.8 : Master Transcription Regulators

    Master transcription regulators are regulatory proteins that are predominantly responsible for regulating the expression of multiple genes. Often these ...

    2.2K views
    11.9 : Regulated mRNA Transport02:22

    11.9 : Regulated mRNA Transport

    In eukaryotes, transcription and translation are compartmentalized; an mRNA is first synthesized in the nucleus and then selectively transported to the ...

    2.8K views
    11.10 : mRNA Stability and Gene Expression02:51

    11.10 : mRNA Stability and Gene Expression

    The structure and stability of mRNA molecules regulates gene expression, as mRNAs are a key step in the pathway from gene to protein. In eukaryotes, the ...

    2.8K views
    11.11 : MicroRNAs01:22

    11.11 : MicroRNAs

    MicroRNA (miRNA) are short, regulatory RNA transcribed from introns (non-coding regions of a gene) or intergenic regions (stretches of DNA present between ...

    2.9K views
    11.12 : Small interfering RNAs (siRNA)02:30

    11.12 : Small interfering RNAs (siRNA)

    Small interfering RNAs, or siRNAs, are short regulatory RNA molecules that can silence genes post-transcriptionally, as well as the transcriptional ...

    3.4K views
    11.13 : lncRNA - Long Non-coding RNAs02:39

    11.13 : lncRNA - Long Non-coding RNAs

    In humans, more than 80% of the genome gets transcribed. However, only around 2% of the genome codes for proteins. The remaining part produces non-coding ...

    2.7K views
    11.14 : Epigenetic Regulation01:37

    11.14 : Epigenetic Regulation

    Epigenetic changes alter the physical structure of the DNA without changing the genetic sequence and often regulate whether genes are turned on or off. ...

    3.0K views
    JoVE Logo

    Privacy

    Terms of Use

    Policies

    Contact Us

    Recommend to library

    JoVE NEWSLETTERS

    Research

    Education

    Authors

    Librarians

    ABOUT JoVE

    Copyright © 2025 MyJoVE Corporation. All rights reserved