Science Education - Advanced Biology
Developmental Biology

An Introduction to Developmental Genetics
Development is the complex process through which a single-celled embryo transforms into a multicellular organism. Developmental processes are guided by ...

Gene Silencing with Morpholinos
Morpholino-mediated gene silencing is a common technique used to study roles of specific genes during development. Morpholinos inhibit gene expression by ...

Genetic Engineering of Model Organisms
Transgenesis, or the use of genetic engineering to alter gene expression, is widely used in the field of developmental biology. Scientists use a number of ...

An Introduction to Molecular Developmental Biology
Molecular signals play a major role in the complex processes occurring during embryonic development. These signals regulate activities such as cell ...

Explant Culture for Developmental Studies
Explant culture is a technique in which living cells or tissues are removed from an embryo for continued development outside of the organism. This ex vivo ...

Whole-Mount In Situ Hybridization
Whole-mount in situ hybridization (WMISH) is a common technique used for visualizing the location of expressed RNAs in embryos. In this process, ...

An Introduction to Stem Cell Biology
Cells that can differentiate into a variety of cell types, known as stem cells, are at the center of one of the most exciting fields of science today. ...

Embryonic Stem Cell Culture and Differentiation
Culturing embryonic stem (ES) cells requires conditions that maintain these cells in an undifferentiated state to preserve their capacity for self-renewal ...

Induced Pluripotency
Induced pluripotent stem cells (iPSCs) are somatic cells that have been genetically reprogrammed to form undifferentiated stem cells. Like embryonic stem ...

An Introduction to Organogenesis
Organogenesis is the process by which organs arise from one of three germ layers during the later stages of embryonic development. Researchers studying ...

Fate Mapping
Fate mapping is a technique used to understand how embryonic cells divide, differentiate, and migrate during development. In classic fate mapping ...

Transplantation Studies
Many developmental biologists are interested in the molecular signals and cellular interactions that induce a group of cells to develop into a particular ...

An Introduction to Aging and Regeneration
Tissues are maintained through a balance of cellular aging and regeneration. Aging refers to the gradual loss of cellular function, and regeneration is ...

Invertebrate Lifespan Quantification
Many animals naturally stop growing upon reaching adulthood, after which they undergo aging or "senescence" until dying. The amount of time between an ...

Tissue Regeneration with Somatic Stem Cells
Somatic or adult stem cells, like embryonic stem cells, are capable of self-renewal but demonstrate a restricted differentiation potential. Nonetheless, ...