Muscle Development and Regeneration Program
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Stage-specific modulation of skeletal myogenesis by inhibitors of nuclear deacetylases.
Proceedings of the National Academy of Sciences of the United States of America May, 2002 | Pubmed ID: 12032356
Activation of MyoD-dependent transcription by cdk9/cyclin T2.
Oncogene Jun, 2002 | Pubmed ID: 12037670
A myogenic differentiation checkpoint activated by genotoxic stress.
Nature genetics Dec, 2002 | Pubmed ID: 12415271
Association of ataxia telangiectasia mutated (ATM) gene mutation/deletion with rhabdomyosarcoma.
Cancer biology & therapy Jan-Feb, 2003 | Pubmed ID: 12673126
Endothelial activation by angiotensin II through NFkappaB and p38 pathways: Involvement of NFkappaB-inducible kinase (NIK), free oxygen radicals, and selective inhibition by aspirin.
Journal of cellular physiology Jun, 2003 | Pubmed ID: 12704649
Deacetylase recruitment by the C/H3 domain of the acetyltransferase p300.
Oncogene Mar, 2004 | Pubmed ID: 14968110
Deacetylase inhibitors increase muscle cell size by promoting myoblast recruitment and fusion through induction of follistatin.
Developmental cell May, 2004 | Pubmed ID: 15130492
p38 pathway targets SWI-SNF chromatin-remodeling complex to muscle-specific loci.
Nature genetics Jul, 2004 | Pubmed ID: 15208625
Differentiation-induced radioresistance in muscle cells.
Molecular and cellular biology Jul, 2004 | Pubmed ID: 15226436
Phosphorylation-dependent degradation of p300 by doxorubicin-activated p38 mitogen-activated protein kinase in cardiac cells.
Molecular and cellular biology Apr, 2005 | Pubmed ID: 15767673
Signaling to the chromatin during skeletal myogenesis: novel targets for pharmacological modulation of gene expression.
Seminars in cell & developmental biology Aug-Oct, 2005 | Pubmed ID: 16129633
The epigenetic network regulating muscle development and regeneration.
Journal of cellular physiology Apr, 2006 | Pubmed ID: 16155926
MyoD recruits the cdk9/cyclin T2 complex on myogenic-genes regulatory regions.
Journal of cellular physiology Mar, 2006 | Pubmed ID: 16245309
p38-dependent phosphorylation of the mRNA decay-promoting factor KSRP controls the stability of select myogenic transcripts.
Molecular cell Dec, 2005 | Pubmed ID: 16364914
A two-hit mechanism for pre-mitotic arrest of cancer cell proliferation by a polyamide-alkylator conjugate.
Cell cycle (Georgetown, Tex.) Jul, 2006 | Pubmed ID: 16861886
DNA damage and cellular differentiation: more questions than responses.
Journal of cellular physiology Dec, 2007 | Pubmed ID: 17894406
Functional interdependence at the chromatin level between the MKK6/p38 and IGF1/PI3K/AKT pathways during muscle differentiation.
Molecular cell Oct, 2007 | Pubmed ID: 17964260
The ER-bound RING finger protein 5 (RNF5/RMA1) causes degenerative myopathy in transgenic mice and is deregulated in inclusion body myositis.
PloS one , 2008 | Pubmed ID: 18270596
Epigenetic drugs in the treatment of skeletal muscle atrophy.
Current opinion in clinical nutrition and metabolic care May, 2008 | Pubmed ID: 18403918
Regenerative pharmacology in the treatment of genetic diseases: the paradigm of muscular dystrophy.
The international journal of biochemistry & cell biology Apr, 2009 | Pubmed ID: 18804548
HDAC2 blockade by nitric oxide and histone deacetylase inhibitors reveals a common target in Duchenne muscular dystrophy treatment.
Proceedings of the National Academy of Sciences of the United States of America Dec, 2008 | Pubmed ID: 19047631
Nitric oxide deficiency determines global chromatin changes in Duchenne muscular dystrophy.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology Jul, 2009 | Pubmed ID: 19264835
Chromatin: the interface between extrinsic cues and the epigenetic regulation of muscle regeneration.
Trends in cell biology Jun, 2009 | Pubmed ID: 19394225
A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.
Developmental cell Dec, 2009 | Pubmed ID: 20059953
Switch NFix developmental myogenesis.
Developmental cell Mar, 2010 | Pubmed ID: 20230743
HDACs and sirtuins: targets for new pharmacological interventions in human diseases.
Pharmacological research : the official journal of the Italian Pharmacological Society Jul, 2010 | Pubmed ID: 20471557
SWI/SNF complexes, chromatin remodeling and skeletal myogenesis: it's time to exchange!
Experimental cell research Nov, 2010 | Pubmed ID: 20553711
Epigenetic regulation of skeletal myogenesis.
Organogenesis Jan-Mar, 2010 | Pubmed ID: 20592865
TNF/p38α/polycomb signaling to Pax7 locus in satellite cells links inflammation to the epigenetic control of muscle regeneration.
Cell stem cell Oct, 2010 | Pubmed ID: 20887952
An evolutionarily acquired genotoxic response discriminates MyoD from Myf5, and differentially regulates hypaxial and epaxial myogenesis.
EMBO reports Feb, 2011 | Pubmed ID: 21212806
Selective control of Pax7 expression by TNF-activated p38α/polycomb repressive complex 2 (PRC2) signaling during muscle satellite cell differentiation.
Cell cycle (Georgetown, Tex.) Jan, 2011 | Pubmed ID: 21220942
Differentiation of human rhabdomyosarcoma RD cells is regulated by reciprocal, functional interactions between myostatin, p38 and extracellular regulated kinase signalling pathways.
European journal of cancer (Oxford, England : 1990) May, 2011 | Pubmed ID: 21273059
Histone deacetylase inhibitors in the treatment of muscular dystrophies: epigenetic drugs for genetic diseases.
Molecular medicine (Cambridge, Mass.) May-Jun, 2011 | Pubmed ID: 21308150
Phosphoryl-EZH-ion.
Cell stem cell Mar, 2011 | Pubmed ID: 21362566
Coordination of cell cycle, DNA repair and muscle gene expression in myoblasts exposed to genotoxic stress.
Cell cycle (Georgetown, Tex.) Jul, 2011 | Pubmed ID: 21685725
Chromatin regulated interchange between polycomb repressive complex 2 (PRC2)-Ezh2 and PRC2-Ezh1 complexes controls myogenin activation in skeletal muscle cells.
Epigenetics & chromatin , 2011 | Pubmed ID: 21892963
Signal-dependent incorporation of MyoD-BAF60c into Brg1-based SWI/SNF chromatin-remodelling complex.
The EMBO journal Jan, 2012 | Pubmed ID: 22068056
SIRT1 signaling as potential modulator of skeletal muscle diseases.
Current opinion in pharmacology Jun, 2012 | Pubmed ID: 22401932
Epigenetic control of reprogramming and cellular differentiation.
Comparative and functional genomics , 2012 | Pubmed ID: 23019420
Myosin phosphatase modulates the cardiac cell fate by regulating the subcellular localization of Nkx2.5 in a Wnt/Rho-associated protein kinase-dependent pathway.
Circulation research Jan, 2013 | Pubmed ID: 23168335
BAF60 A, B, and Cs of muscle determination and renewal.
Genes & development Dec, 2012 | Pubmed ID: 23222103
A novel AMPK-dependent FoxO3A-SIRT3 intramitochondrial complex sensing glucose levels.
Cellular and molecular life sciences : CMLS Jun, 2013 | Pubmed ID: 23283301
Studying arrhythmogenic right ventricular dysplasia with patient-specific iPSCs.
Nature Feb, 2013 | Pubmed ID: 23354045
Epigenetic reprogramming of human embryonic stem cells into skeletal muscle cells and generation of contractile myospheres.
Cell reports Mar, 2013 | Pubmed ID: 23478022
Fibroadipogenic progenitors mediate the ability of HDAC inhibitors to promote regeneration in dystrophic muscles of young, but not old Mdx mice.
EMBO molecular medicine Apr, 2013 | Pubmed ID: 23505062
Preclinical studies in the mdx mouse model of duchenne muscular dystrophy with the histone deacetylase inhibitor givinostat.
Molecular medicine (Cambridge, Mass.) , 2013 | Pubmed ID: 23552722
Epigenetic control of skeletal muscle regeneration: Integrating genetic determinants and environmental changes.
The FEBS journal Sep, 2013 | Pubmed ID: 23745685
Coordinate Nodal and BMP inhibition directs Baf60c-dependent cardiomyocyte commitment.
Genes & development Nov, 2013 | Pubmed ID: 24186978
Pharmacological inhibition of EZH2 as a promising differentiation therapy in embryonal RMS.
BMC cancer , 2014 | Pubmed ID: 24575771
"Mix of Mics"- Phenotypic and Biological Heterogeneity of "Multipotent" Muscle Interstitial Cells (MICs).
Journal of stem cell research & therapy Oct, 2012 | Pubmed ID: 24634800
HDAC-regulated myomiRs control BAF60 variant exchange and direct the functional phenotype of fibro-adipogenic progenitors in dystrophic muscles.
Genes & development Apr, 2014 | Pubmed ID: 24682306
Nitric oxide and histone acetylation-shaping craniofacial development.
Chemistry & biology May, 2014 | Pubmed ID: 24856136
Redox or death: checking on fetal myogenesis.
Developmental cell May, 2014 | Pubmed ID: 24871943
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