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Cancer Immunology Program
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Human B cells secrete granzyme B when recognizing viral antigens in the context of the acute phase cytokine IL-21.
Journal of immunology (Baltimore, Md. : 1950) Aug, 2009 | Pubmed ID: 19592644
CD5+ B cells from individuals with systemic lupus erythematosus express granzyme B.
European journal of immunology Jul, 2010 | Pubmed ID: 20394077
Human B cells differentiate into granzyme B-secreting cytotoxic B lymphocytes upon incomplete T-cell help.
Immunology and cell biology Apr, 2012 | Pubmed ID: 21808264
Activated mouse B cells lack expression of granzyme B.
Journal of immunology (Baltimore, Md. : 1950) Apr, 2012 | Pubmed ID: 22427643
Why do human B cells secrete granzyme B? Insights into a novel B-cell differentiation pathway.
Oncoimmunology Nov, 2012 | Pubmed ID: 23243600
Interleukin 21-induced granzyme B-expressing B cells infiltrate tumors and regulate T cells.
Cancer research Apr, 2013 | Pubmed ID: 23384943
B-CLL cells acquire APC- and CTL-like phenotypic characteristics after stimulation with CpG ODN and IL-21.
International immunology Jul, 2014 | Pubmed ID: 24497611
A Method for Detecting Intracellular Perforin in Mouse Lymphocytes.
Journal of immunology (Baltimore, Md. : 1950) Dec, 2014 | Pubmed ID: 25348626
Peter MacCallum Cancer Centre
Magdalena Hagn1,
Vivien R. Sutton1,
Joseph A. Trapani1
1Cancer Immunology Program, Peter MacCallum Cancer Centre
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