Cathrin Brisken

Hormonal control of alveolar development and its implications for breast carcinogenesis.

The signaling domain of the erythropoietin receptor rescues prolactin receptor-mutant mammary epithelium.

Prolactin signaling and Stat5: going their own separate ways?

IGF-2 is a mediator of prolactin-induced morphogenesis in the breast.

Using gene expression arrays to elucidate transcriptional profiles underlying prolactin function.

Canonical WNT signaling promotes mammary placode development and is essential for initiation of mammary gland morphogenesis.

Identification of molecular apocrine breast tumours by microarray analysis.

p21WAF1/Cip1 is a negative transcriptional regulator of Wnt4 expression downstream of Notch1 activation.

Paracrine signaling through the epithelial estrogen receptor alpha is required for proliferation and morphogenesis in the mammary gland.

Increased Wnt signaling triggers oncogenic conversion of human breast epithelial cells by a Notch-dependent mechanism.

Alveolar and lactogenic differentiation.

Amphiregulin is an essential mediator of estrogen receptor alpha function in mammary gland development.

An oestrogen-dependent model of breast cancer created by transformation of normal human mammary epithelial cells.

Stem cells and the stem cell niche in the breast: an integrated hormonal and developmental perspective.

The Ret receptor tyrosine kinase pathway functionally interacts with the ERalpha pathway in breast cancer.

The epithelial-mesenchymal transition generates cells with properties of stem cells.

Epidermal receptor activator of NF-kappaB ligand controls Langerhans cells numbers and proliferation.

What signals operate in the mammary niche?

The tumor suppressor p53 regulates polarity of self-renewing divisions in mammary stem cells.

From normal cell types to malignant phenotypes.

Amphiregulin mediates self-renewal in an immortal mammary epithelial cell line with stem cell characteristics.

Stem cells in chemical carcinogenesis.

Two distinct mechanisms underlie progesterone-induced proliferation in the mammary gland.

Cyclin D1 enhances the response to estrogen and progesterone by regulating progesterone receptor expression.

Epithelial-mesenchymal transition-derived cells exhibit multilineage differentiation potential similar to mesenchymal stem cells.

Control of hair follicle cell fate by underlying mesenchyme through a CSL-Wnt5a-FoxN1 regulatory axis.

Hormone action in the mammary gland.

High hopes for RANKL: will the mouse model live up to its promise?

Perinatal exposure to bisphenol a increases adult mammary gland progesterone response and cell number.

Paracrine signaling by progesterone.

ID4 regulates mammary gland development by suppressing p38MAPK activity.

ER and PR signaling nodes during mammary gland development.

miR148b is a major coordinator of breast cancer progression in a relapse-associated microRNA signature by targeting ITGA5, ROCK1, PIK3CA, NRAS, and CSF1.

Progesterone/RANKL is a major regulatory axis in the human breast.

Does cancer start in the womb? altered mammary gland development and predisposition to breast cancer due to in utero exposure to endocrine disruptors.

Progesterone signalling in breast cancer: a neglected hormone coming into the limelight.

Monitoring proliferative activities of hormone-like odorants in human breast cancer cells by gene transcription profiling and electrical impedance spectroscopy.

A new Achilles Heel in breast cancer?

Reply to Is progesterone a neutral or protective factor for breast cancer?