Philip Norris

Agreement among HLA antibody detection assays is higher in ever-pregnant donors and improved using a consensus cutoff.

CD4(+) T helper cells and the role they play in viral control.

Labeling antigen-specific CD4(+) T cells with class II MHC oligomers.

Comprehensive analysis of human immunodeficiency virus type 1-specific CD4 responses reveals marked immunodominance of gag and nef and the presence of broadly recognized peptides.

Fine specificity and cross-clade reactivity of HIV type 1 Gag-specific CD4+ T cells.

Heat shock protein-mediated cross-presentation of exogenous HIV antigen on HLA class I and class II.

Beyond help: direct effector functions of human immunodeficiency virus type 1-specific CD4(+) T cells.

A hairpin turn in a class II MHC-bound peptide orients residues outside the binding groove for T cell recognition.

Antagonism of HIV-specific CD4+ T cells by C-terminal truncation of a minimum epitope.

The effects of early antiretroviral therapy and its discontinuation on the HIV-specific antibody response.

The antigenic determinants on HIV p24 for CD4+ T cell inhibiting antibodies as determined by limited proteolysis, chemical modification, and mass spectrometry.

Elevations in IL-10, TNF-alpha, and IFN-gamma from the earliest point of HIV Type 1 infection.

Transfusion-associated microchimerism: a new complication of blood transfusions in severely injured patients.

Influenza viremia and the potential for blood-borne transmission.

Nanoparticle-Based biobarcode amplification assay (BCA) for sensitive and early detection of human immunodeficiency type 1 capsid (p24) antigen.

Loss of T cell responses following long-term cryopreservation.

Comprehensive analysis of west nile virus-specific T cell responses in humans.

Suppression of HIV-1 plasma viral load below detection preserves IL-17 producing T cells in HIV-1 infection.

Interferon and interferon-induced chemokine expression is associated with control of acute viremia in West Nile virus-infected blood donors.

Virus and antibody dynamics in acute west nile virus infection.

Protein kinase C theta regulates stability of the peripheral adhesion ring junction and contributes to the sensitivity of target cell lysis by CTL.

Evidence for persistent low-level viremia in individuals who control human immunodeficiency virus in the absence of antiretroviral therapy.

Long-term in vitro reactivity for human leukocyte antigen antibodies and comparison of detection using serum versus plasma.

Induction of a striking systemic cytokine cascade prior to peak viremia in acute human immunodeficiency virus type 1 infection, in contrast to more modest and delayed responses in acute hepatitis B and C virus infections.

The effect of previous pregnancy and transfusion on HLA alloimmunization in blood donors: implications for a transfusion-related acute lung injury risk reduction strategy.

Understanding loss of donor white blood cell immunogenicity after pathogen reduction: mechanisms of action in ultraviolet illumination and riboflavin treatment.

Kinetics of early T cell receptor signaling regulate the pathway of lytic granule delivery to the secretory domain.

The importance of Foxp3 antibody and fixation/permeabilization buffer combinations in identifying CD4+CD25+Foxp3+ regulatory T cells.

Tregs control the development of symptomatic West Nile virus infection in humans and mice.

A novel human CD4+ T-cell inducer subset with potent immunostimulatory properties.

HIV-Selectest enzyme immunoassay and rapid test: ability to detect seroconversion following HIV-1 infection.

Prevalence of HLA antibodies in remotely transfused or alloexposed volunteer blood donors.

Identification of specificities of antibodies against human leukocyte antigens in blood donors.

HIV+ elite controllers have low HIV-specific T-cell activation yet maintain strong, polyfunctional T-cell responses.

Elevated caspase-3 expression and T-cell activation in elite suppressors.

Human T cell leukemia virus type 1 infection drives spontaneous proliferation of natural killer cells.

Evidence of persistent low-level viremia in long-term HAART-suppressed, HIV-infected individuals.

Low-dose mucosal simian immunodeficiency virus infection restricts early replication kinetics and transmitted virus variants in rhesus monkeys.

CD57 defines a functionally distinct population of mature NK cells in the human CD56dimCD16+ NK-cell subset.

The frequency and specificity of human neutrophil antigen antibodies in a blood donor population.

Effects of blood sample age at time of separation on measured cytokine concentrations in human plasma.

A low T regulatory cell response may contribute to both viral control and generalized immune activation in HIV controllers.

Establishing assay cutoffs for HLA antibody screening of apheresis donors.

Properties of stored red blood cells: understanding immune and vascular reactivity.

[West Nile virus - I. conquest of the West].

[West Nile virus. II. Immunopathophysiology in humans].

Immune and Genetic Correlates of Vaccine Protection Against Mucosal Infection by SIV in Monkeys.

The effect of HIV infection and HAART on inflammatory biomarkers in a population-based cohort of women.

Cross-sectional detection of acute HIV infection: timing of transmission, inflammation and antiretroviral therapy.

Multisite comparison of high-sensitivity multiplex cytokine assays.

Identifying the early post-HIV antibody seroconversion period.

Association between HLA class I and class II alleles and the outcome of West Nile virus infection: an exploratory study.

Transfusion-related acute lung injury: incidence and risk factors.

Expansion of CD8+ T cells lacking Sema4D/CD100 during HIV-1 infection identifies a subset of T cells with decreased functional capacity.

Sensitive detection assays for influenza RNA do not reveal viremia in US blood donors.

Distinct roles of trauma and transfusion in induction of immune modulation after injury.

Detection of host immune responses in acute phase sera of spontaneous resolution versus persistent hepatitis C virus infection.

Potential cardiovascular disease risk markers among HIV-infected women initiating antiretroviral treatment.

Soluble mediators of inflammation in HIV and their implications for therapeutics and vaccine development.

Lower-sensitivity and avidity modifications of the vitros anti-HIV 1+2 assay for detection of recent HIV infections and incidence estimation.

Association of subclinical atherosclerosis with lipid levels amongst antiretroviral-treated and untreated HIV-infected women in the Women's Interagency HIV study.

IL-1β signaling promotes CNS-intrinsic immune control of West Nile virus infection.

Lot-to-lot variability in HLA antibody screening using a multiplexed bead-based assay.

Low-level HLA antibodies do not predict platelet transfusion failure in TRAP study participants.

Treatment-related changes in serum lipids and inflammation: clinical relevance remains unclear. Analyses from the Women's Interagency HIV study.

Immune modulation and lack of alloimmunization following transfusion with pathogen-reduced platelets in mice.

CD57 expression and cytokine production by T cells in lesional and unaffected skin from patients with psoriasis.

Fetal production of growth factors and inflammatory mediators predicts pulmonary hypertension in congenital diaphragmatic hernia.

Leukoreduction and ultraviolet treatment reduce both the magnitude and the duration of the HLA antibody response.

In vitro measures of membrane changes reveal differences between red blood cells stored in saline-adenine-glucose-mannitol and AS-1 additive solutions: a paired study.

Plasma monocyte chemoattractant protein-1 and tumor necrosis factor-α levels predict the presence of coronary artery calcium in HIV-infected individuals independent of traditional cardiovascular risk factors.

IL-1Β enriched monocytes mount massive IL-6 responses to common inflammatory triggers among chronically HIV-1 infected adults on stable anti-retroviral therapy at risk for cardiovascular disease.

Cytokine and chemokine responses in the acute phase of hepatitis B virus replication in naive and previously vaccinated blood and plasma donors.

HIV RNA levels in plasma and cervical-vaginal lavage fluid in elite controllers and HAART recipients.

Exosomes from red blood cell units bind to monocytes and induce proinflammatory cytokines, boosting T-cell responses in vitro.

Reduced CD14 expression on classical monocytes and vascular endothelial adhesion markers independently associate with carotid artery intima media thickness in chronically HIV-1 infected adults on virologically suppressive anti-retroviral therapy.

Monocytes expand with immune dysregulation and is associated with insulin resistance in older individuals with chronic HIV.

Increased frequency of Tim-3 expressing T cells is associated with symptomatic West Nile virus infection.

Prospective study on the clinical course and outcomes in transfusion-related acute lung injury*.

Galectin-9 is rapidly released during acute HIV-1 infection and remains sustained at high levels despite viral suppression even in elite controllers.

West Nile virus nucleic acid persistence in whole blood months after clearance in plasma: implication for transfusion and transplantation safety.

A CD4+ T cell antagonist epitope down-regulates activating signaling proteins, up-regulates inhibitory signaling proteins and abrogates HIV-specific T cell function.

Albuminuria is associated with elevated acute phase reactants and proinflammatory markers in HIV-infected patients receiving suppressive combination antiretroviral therapy.

Role of microRNA modulation in the interferon-α/ribavirin suppression of HIV-1 in vivo.

Downregulation of Cytokines and Chemokines by GB Virus C After Transmission Via Blood Transfusion in HIV-Positive Blood Recipients.

Recipient clinical risk factors predominate in possible transfusion-related acute lung injury.

Soluble T Cell Immunoglobulin Mucin Domain 3 Is Shed from CD8+ T Cells by the Sheddase ADAM10, Is Increased in Plasma during Untreated HIV Infection, and Correlates with HIV Disease Progression.