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Department of Neurology
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Medulloblastoma growth inhibition by hedgehog pathway blockade.
Science (New York, N.Y.) Aug, 2002 | Pubmed ID: 12202832
Inhibition of Hedgehog signaling by direct binding of cyclopamine to Smoothened.
Genes & development Nov, 2002 | Pubmed ID: 12414725
A defective response to Hedgehog signaling in disorders of cholesterol biosynthesis.
Nature genetics Apr, 2003 | Pubmed ID: 12652302
Hedgehog signaling in the murine melanoma microenvironment.
Angiogenesis , 2007 | Pubmed ID: 17762973
Reappraisal of the role of the DRD3 gene in essential tremor.
Parkinsonism & related disorders Aug, 2008 | Pubmed ID: 18316228
Prevalence of unilateral tremor in autosomal dominant essential tremor.
Movement disorders : official journal of the Movement Disorder Society Jan, 2009 | Pubmed ID: 18973247
Positive family history of essential tremor influences the motor phenotype of Parkinson's disease.
Movement disorders : official journal of the Movement Disorder Society Nov, 2009 | Pubmed ID: 19795470
Activation of the Hedgehog pathway in pilocytic astrocytomas.
Neuro-oncology Aug, 2010 | Pubmed ID: 20223881
Transventricular delivery of Sonic hedgehog is essential to cerebellar ventricular zone development.
Proceedings of the National Academy of Sciences of the United States of America May, 2010 | Pubmed ID: 20400693
Clustering of dystonia in some pedigrees with autosomal dominant essential tremor suggests the existence of a distinct subtype of essential tremor.
BMC neurology , 2010 | Pubmed ID: 20670416
Lipid modifications of Sonic hedgehog ligand dictate cellular reception and signal response.
PloS one , 2011 | Pubmed ID: 21747935
Identification of blood protein biomarkers that aid in the clinical assessment of patients with malignant glioma.
International journal of oncology Feb, 2012 | Pubmed ID: 22307528
Widespread contribution of Gdf7 lineage to cerebellar cell types and implications for hedgehog-driven medulloblastoma formation.
PloS one , 2012 | Pubmed ID: 22539980
Six3 cooperates with Hedgehog signaling to specify ventral telencephalon by promoting early expression of Foxg1a and repressing Wnt signaling.
Development (Cambridge, England) Jul, 2012 | Pubmed ID: 22736245
Subgroup-specific structural variation across 1,000 medulloblastoma genomes.
Nature Aug, 2012 | Pubmed ID: 22832581
Voltage-gated potassium channel EAG2 controls mitotic entry and tumor growth in medulloblastoma via regulating cell volume dynamics.
Genes & development Aug, 2012 | Pubmed ID: 22855790
Identification of Hedgehog pathway responsive glioblastomas by isocitrate dehydrogenase mutation.
Cancer letters Jan, 2013 | Pubmed ID: 23063752
TERT promoter mutations are highly recurrent in SHH subgroup medulloblastoma.
Acta neuropathologica Dec, 2013 | Pubmed ID: 24174164
Vanderbilt University
Vanderbilt University Medical Center
Veteran Affairs TVHS
Xi Huang1,
Anuraag Sarangi2,
Tatiana Ketova1,
Ying Litingtung1,
Michael K. Cooper2,
Chin Chiang1
1Department of Cell and Developmental Biology, Vanderbilt University,
2Department of Neurology, Vanderbilt University
J. Geraldo Valadez1,
Anuraag Sarangi1,
Christopher J. Lundberg1,
Michael K. Cooper1,2,3
1Department of Neurology, Vanderbilt University Medical Center,
2Vanderbilt Ingram Cancer Center, Vanderbilt University Medical Center,
3Neurology Service, Veteran Affairs TVHS
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