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Cre recombinase-controlled expression of the mb-1 allele.
Genesis (New York, N.Y. : 2000) Feb, 2002 | Pubmed ID: 11857807
The procaspase-8 isoform, procaspase-8L, recruited to the BAP31 complex at the endoplasmic reticulum.
Proceedings of the National Academy of Sciences of the United States of America Apr, 2002 | Pubmed ID: 11917123
The role of SHIP in mast cell degranulation and IgE-induced mast cell survival.
Immunology letters Jun, 2002 | Pubmed ID: 12008029
B cell progenitors are arrested in maturation but have intact VDJ recombination in the absence of Ig-alpha and Ig-beta.
Journal of immunology (Baltimore, Md. : 1950) Jul, 2002 | Pubmed ID: 12097390
BCR mutants deficient in ligand-independent and more sensitive for ligand-dependent signaling.
European journal of immunology Jun, 2002 | Pubmed ID: 12115644
Inducible gene deletion reveals different roles for B-Raf and Raf-1 in B-cell antigen receptor signalling.
The EMBO journal Nov, 2002 | Pubmed ID: 12411479
The adaptor protein SLP-65 acts as a tumor suppressor that limits pre-B cell expansion.
Nature immunology Jan, 2003 | Pubmed ID: 12436112
Hydrogen peroxide as second messenger in lymphocyte activation.
Nature immunology Dec, 2002 | Pubmed ID: 12447370
Amplification of B cell antigen receptor signaling by a Syk/ITAM positive feedback loop.
Molecular cell Nov, 2002 | Pubmed ID: 12453414
Activation of T cells via tumor antigen specific chimeric receptors: the role of the intracellular signaling domain.
International journal of cancer Jan, 2003 | Pubmed ID: 12471624
Essential role of Src-family protein tyrosine kinases in NF-kappaB activation during B cell development.
Nature immunology Mar, 2003 | Pubmed ID: 12563261
NF-kappaB is required for cell death induction by latent membrane protein 1 of Epstein-Barr virus.
Cellular signalling Apr, 2003 | Pubmed ID: 12618217
Genetic changes occurring in established tumors rapidly stimulate new antibody responses.
Proceedings of the National Academy of Sciences of the United States of America Apr, 2003 | Pubmed ID: 12702750
Deficiency of the adaptor SLP-65 in pre-B-cell acute lymphoblastic leukaemia.
Nature May, 2003 | Pubmed ID: 12761551
Establishment of immortalized human hepatic stellate scavenger cells to develop bioartificial livers.
Transplantation Jun, 2003 | Pubmed ID: 12811248
Bruton's tyrosine kinase cooperates with the B cell linker protein SLP-65 as a tumor suppressor in Pre-B cells.
The Journal of experimental medicine Jul, 2003 | Pubmed ID: 12835482
A high-molecular-weight complex of membrane proteins BAP29/BAP31 is involved in the retention of membrane-bound IgD in the endoplasmic reticulum.
Proceedings of the National Academy of Sciences of the United States of America Aug, 2003 | Pubmed ID: 12886015
Importance of TRF1 for functional telomere structure.
The Journal of biological chemistry Jan, 2004 | Pubmed ID: 14559908
B cell defects in SLP65/BLNK-deficient mice can be partially corrected by the absence of CD22, an inhibitory coreceptor for BCR signaling.
European journal of immunology Dec, 2003 | Pubmed ID: 14635051
Identification of a pre-BCR lacking surrogate light chain.
The Journal of experimental medicine Dec, 2003 | Pubmed ID: 14638847
Identification of novel ERK-mediated feedback phosphorylation sites at the C-terminus of B-Raf.
Oncogene Dec, 2003 | Pubmed ID: 14654779
Activation of the CKI-CDK-Rb-E2F pathway in full genome hepatitis C virus-expressing cells.
The Journal of biological chemistry Apr, 2004 | Pubmed ID: 14747471
A revised and complete map of the chicken c-mil/raf-1 locus.
Oncogene Apr, 2004 | Pubmed ID: 14968114
Feedback regulation of lymphocyte signalling.
Nature reviews. Immunology Apr, 2004 | Pubmed ID: 15057785
B cell antigen receptor assembly and Syk activation in the S2 cell reconstitution system.
Immunology letters Mar, 2004 | Pubmed ID: 15081529
Functional folding of a cytoplasmic single-chain variable fragment and its use as elutable protein purification tag.
Immunology letters Mar, 2004 | Pubmed ID: 15081544
B-cell signal transduction: tyrosine phosphorylation, kinase activity, and calcium mobilization.
Methods in molecular biology (Clifton, N.J.) , 2004 | Pubmed ID: 15146122
Perspectives on the nature of BCR-mediated survival signals.
Molecular cell Jun, 2004 | Pubmed ID: 15200948
Adenosine and cAMP are potent inhibitors of the NF-kappa B pathway downstream of immunoreceptors.
European journal of immunology Jan, 2005 | Pubmed ID: 15580656
Reversible switching of immunoglobulin hypermutation machinery in a chicken B cell line.
Biochemical and biophysical research communications Feb, 2005 | Pubmed ID: 15629431
A leucine zipper in the N terminus confers membrane association to SLP-65.
Nature immunology Feb, 2005 | Pubmed ID: 15654340
Postnatal isl1+ cardioblasts enter fully differentiated cardiomyocyte lineages.
Nature Feb, 2005 | Pubmed ID: 15703750
B cell signaling and tumorigenesis.
Annual review of immunology , 2005 | Pubmed ID: 15771577
Two dimensional Blue Native-/SDS-PAGE analysis of SLP family adaptor protein complexes.
Immunology letters Apr, 2006 | Pubmed ID: 16356554
Human T-cell leukemia virus type-I oncoprotein Tax inhibits Fas-mediated apoptosis by inducing cellular FLIP through activation of NF-kappaB.
Genes to cells : devoted to molecular & cellular mechanisms Feb, 2006 | Pubmed ID: 16436054
Canonical NF-kappaB activity, dispensable for B cell development, replaces BAFF-receptor signals and promotes B cell proliferation upon activation.
Immunity Jun, 2006 | Pubmed ID: 16782029
Identification of disulfide bonds in the Ig-alpha/Ig-beta component of the B cell antigen receptor using the Drosophila S2 cell reconstitution system.
International immunology Sep, 2006 | Pubmed ID: 16877534
Association of protein kinase C-delta with the B cell antigen receptor complex.
Cellular signalling Apr, 2007 | Pubmed ID: 17098397
Survival of liver failure pigs by transplantation of reversibly immortalized human hepatocytes with Tamoxifen-mediated self-recombination.
Journal of hepatology Jul, 2007 | Pubmed ID: 17434229
Yin Yang 1 is a critical regulator of B-cell development.
Genes & development May, 2007 | Pubmed ID: 17504937
Immunoreceptors and integrins.
Immunological reviews Aug, 2007 | Pubmed ID: 17624940
Mutations of the Igbeta gene cause agammaglobulinemia in man.
The Journal of experimental medicine Sep, 2007 | Pubmed ID: 17709424
The TCR binding site does move.
Proceedings of the National Academy of Sciences of the United States of America Oct, 2007 | Pubmed ID: 17925433
The kinase Syk as an adaptor controlling sustained calcium signalling and B-cell development.
The EMBO journal May, 2008 | Pubmed ID: 18369315
SLP-65 regulates immunoglobulin light chain gene recombination through the PI(3)K-PKB-Foxo pathway.
Nature immunology Jun, 2008 | Pubmed ID: 18488031
Functional analysis of histone methyltransferase g9a in B and T lymphocytes.
Journal of immunology (Baltimore, Md. : 1950) Jul, 2008 | Pubmed ID: 18566414
Enhanced B-cell activation mediated by TLR4 and BCR crosstalk.
European journal of immunology Sep, 2008 | Pubmed ID: 18819072
Clustering models.
Advances in experimental medicine and biology , 2008 | Pubmed ID: 19065784
Genomic instability resulting from Blm deficiency compromises development, maintenance, and function of the B cell lineage.
Journal of immunology (Baltimore, Md. : 1950) Jan, 2009 | Pubmed ID: 19109166
Regulation of B-cell proliferation and differentiation by pre-B-cell receptor signalling.
Nature reviews. Immunology Mar, 2009 | Pubmed ID: 19240758
Molecular components of the B-cell antigen receptor complex of the IgM class. 1990.
Journal of immunology (Baltimore, Md. : 1950) Aug, 2009 | Pubmed ID: 19620316
Induction of B-cell development in adult mice reveals the ability of bone marrow to produce B-1a cells.
Blood Dec, 2009 | Pubmed ID: 19812384
Autoinhibition and adapter function of Syk.
Immunological reviews Nov, 2009 | Pubmed ID: 19909371
Analysis of novel phospho-ITAM specific antibodies in a S2 reconstitution system for TCR-CD3 signalling.
Immunology letters May, 2010 | Pubmed ID: 20005895
Voltage control for B cell activation.
Nature immunology Mar, 2010 | Pubmed ID: 20157299
Arginine methylation of the B cell antigen receptor promotes differentiation.
The Journal of experimental medicine Apr, 2010 | Pubmed ID: 20231378
N-linked glycosylation selectively regulates autonomous precursor BCR function.
Nature immunology Aug, 2010 | Pubmed ID: 20622883
Oligomeric organization of the B-cell antigen receptor on resting cells.
Nature Sep, 2010 | Pubmed ID: 20818374
The dissociation activation model of B cell antigen receptor triggering.
FEBS letters Dec, 2010 | Pubmed ID: 20920502
Syk is a dual-specificity kinase that self-regulates the signal output from the B-cell antigen receptor.
Proceedings of the National Academy of Sciences of the United States of America Oct, 2010 | Pubmed ID: 20940318
B cell homeostasis and plasma cell homing controlled by Krüppel-like factor 2.
Proceedings of the National Academy of Sciences of the United States of America Jan, 2011 | Pubmed ID: 21187409
B cells that produce immunoglobulin E mediate colitis in BALB/c mice.
Gastroenterology Jan, 2012 | Pubmed ID: 21983080
Bacillus subtilis MreB orthologs self-organize into filamentous structures underneath the cell membrane in a heterologous cell system.
PloS one , 2011 | Pubmed ID: 22069484
Drosophila S2 Schneider cells: a useful tool for rebuilding and redesigning approaches in synthetic biology.
Methods in molecular biology (Clifton, N.J.) , 2012 | Pubmed ID: 22083752
The SH2-domain of SHIP1 interacts with the SHIP1 C-terminus: impact on SHIP1/Ig-α interaction.
Biochimica et biophysica acta Feb, 2012 | Pubmed ID: 22182704
The E3 ubiquitin ligase Mule acts through the ATM-p53 axis to maintain B lymphocyte homeostasis.
The Journal of experimental medicine Jan, 2012 | Pubmed ID: 22213803
Synthetic immune signaling.
Current opinion in biotechnology Oct, 2012 | Pubmed ID: 22326912
Non-cell-autonomous hedgehog signaling promotes murine B lymphopoiesis from hematopoietic progenitors.
Blood Jun, 2012 | Pubmed ID: 22517907
Immunoglobulins drive terminal maturation of splenic dendritic cells.
Proceedings of the National Academy of Sciences of the United States of America Feb, 2013 | Pubmed ID: 23345431
Semi-supervised prediction of SH2-peptide interactions from imbalanced high-throughput data.
PloS one , 2013 | Pubmed ID: 23690949
CD22 ligand-binding and signaling domains reciprocally regulate B-cell Ca2+ signaling.
Proceedings of the National Academy of Sciences of the United States of America Jul, 2013 | Pubmed ID: 23836650
Matching cellular dimensions with molecular sizes.
Nature immunology Aug, 2013 | Pubmed ID: 23867923
The serine/threonine phosphatase PP4 is required for pro-B cell development through its promotion of immunoglobulin VDJ recombination.
PloS one , 2013 | Pubmed ID: 23874770
Inhibition of mTORC1 by astrin and stress granules prevents apoptosis in cancer cells.
Cell Aug, 2013 | Pubmed ID: 23953116
Proximity ligation assay for high-content profiling of cell signaling pathways on a microfluidic chip.
Molecular & cellular proteomics : MCP Dec, 2013 | Pubmed ID: 24072685
Pre-clustering of the B cell antigen receptor demonstrated by mathematically extended electron microscopy.
Frontiers in immunology , 2013 | Pubmed ID: 24367367
Michael Neuberger (1953-2013).
Immunity Dec, 2013 | Pubmed ID: 24479157
Signaling circuits in early B-cell development.
Advances in immunology , 2014 | Pubmed ID: 24507157
The protein tyrosine phosphatase PTP1B is a negative regulator of CD40 and BAFF-R signaling and controls B cell autoimmunity.
The Journal of experimental medicine Mar, 2014 | Pubmed ID: 24590766
Pillars article: antigen receptor tail clue. Nature. 1989. 338: 383-384.
Journal of immunology (Baltimore, Md. : 1950) May, 2014 | Pubmed ID: 24748635
MIF promotes B cell chemotaxis through the receptors CXCR4 and CD74 and ZAP-70 signaling.
Journal of immunology (Baltimore, Md. : 1950) Jun, 2014 | Pubmed ID: 24760155
The ligand-binding domain of Siglec-G is crucial for its selective inhibitory function on B1 cells.
Journal of immunology (Baltimore, Md. : 1950) Jun, 2014 | Pubmed ID: 24790146
The role of the Syk/Shp-1 kinase-phosphatase equilibrium in B cell development and signaling.
Journal of immunology (Baltimore, Md. : 1950) Jul, 2014 | Pubmed ID: 24899508
B cell activation involves nanoscale receptor reorganizations and inside-out signaling by Syk.
eLife Jun, 2014 | Pubmed ID: 24963139
PDK1 regulates B cell differentiation and homeostasis.
Proceedings of the National Academy of Sciences of the United States of America Jul, 2014 | Pubmed ID: 24979759
Production of IgG autoantibody requires expression of activation-induced deaminase in early-developing B cells in a mouse model of SLE.
European journal of immunology Oct, 2014 | Pubmed ID: 25044405
The AP-1 transcription factor Fra1 inhibits follicular B cell differentiation into plasma cells.
The Journal of experimental medicine Oct, 2014 | Pubmed ID: 25288397
Suboptimal B-cell antigen receptor signaling activity in vivo elicits germinal center counterselection mechanisms.
European journal of immunology Feb, 2015 | Pubmed ID: 25382621
The nanoscale organization of the B lymphocyte membrane.
Biochimica et biophysica acta Apr, 2015 | Pubmed ID: 25450974
CD19 and BAFF-R can signal to promote B-cell survival in the absence of Syk.
The EMBO journal Apr, 2015 | Pubmed ID: 25630702
Preface to special issue on nanoscale membrane organisations.
Biochimica et biophysica acta Apr, 2015 | Pubmed ID: 25677899
Fundamental properties of unperturbed haematopoiesis from stem cells in vivo.
Nature Feb, 2015 | Pubmed ID: 25686605
TSC1 activates TGF-β-Smad2/3 signaling in growth arrest and epithelial-to-mesenchymal transition.
Developmental cell Mar, 2015 | Pubmed ID: 25727005
Signalling thresholds and negative B-cell selection in acute lymphoblastic leukaemia.
Nature May, 2015 | Pubmed ID: 25799995
Responsiveness of B cells is regulated by the hinge region of IgD.
Nature immunology May, 2015 | Pubmed ID: 25848865
Erratum: Responsiveness of B cells is regulated by the hinge region of IgD.
Nature immunology Jul, 2015 | Pubmed ID: 26086144
Processing of CD74 by the Intramembrane Protease SPPL2a Is Critical for B Cell Receptor Signaling in Transitional B Cells.
Journal of immunology (Baltimore, Md. : 1950) Aug, 2015 | Pubmed ID: 26157172
Kidins220/ARMS binds to the B cell antigen receptor and regulates B cell development and activation.
The Journal of experimental medicine Sep, 2015 | Pubmed ID: 26324445
B cell antigen receptors of the IgM and IgD classes are clustered in different protein islands that are altered during B cell activation.
Science signaling Sep, 2015 | Pubmed ID: 26373673
Receptor Dissociation and B-Cell Activation.
Current topics in microbiology and immunology , 2016 | Pubmed ID: 26428245
Survival of Igα-Deficient Mature B Cells Requires BAFF-R Function.
Journal of immunology (Baltimore, Md. : 1950) Mar, 2016 | Pubmed ID: 26843325
Corrigendum: Signalling thresholds and negative B-cell selection in acute lymphoblastic leukaemia.
Nature 06, 2016 | Pubmed ID: 26958840
Molecular requirements of the B-cell antigen receptor for sensing monovalent antigens.
The EMBO journal Nov, 2016 | Pubmed ID: 27634959
What goes up must come down: A tripartite Dok-3/Grb2/SHIP1 inhibitory module limits BCR signaling.
European journal of immunology Nov, 2016 | Pubmed ID: 27813071
1, Max-Planck Institute for Immunobiology und Epigenetics,
2Spemann Graduate School of Biology and Medicine (SGBM), University of Freiburg,
3Centre for Biological Signaling Studies, BIOSS, University of Freiburg,
4, Albert-Ludwigs-Universität,
5Institute for Biology III (Mol. Immunology), Albert-Ludwigs-Universität
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