Michael Reth

Max-Planck Institute for Immunobiology und Epigenetics

Affiliated withMax-Planck Institute for Immunobiology und Epigenetics University of Freiburg Albert-Ludwigs-Universität

Research Area

Biology

Biography

Michael Reth has not added Biography.
If you are Michael Reth and would like to personalize this page please email our Author Liaison for assistance.

JoVE Journal Publications

ArticleTotal : 1	Year
Publication title	2016

Other Publications

Article	Year
Cre recombinase-controlled expression of the mb-1 allele. Genesis (New York, N.Y. : 2000)\| PubMed ID: 11857807	2002
The procaspase-8 isoform, procaspase-8L, recruited to the BAP31 complex at the endoplasmic reticulum. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 11917123	2002
The role of SHIP in mast cell degranulation and IgE-induced mast cell survival. Immunology letters\| PubMed ID: 12008029	2002
B cell progenitors are arrested in maturation but have intact VDJ recombination in the absence of Ig-alpha and Ig-beta. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 12097390	2002
BCR mutants deficient in ligand-independent and more sensitive for ligand-dependent signaling. European journal of immunology\| PubMed ID: 12115644	2002
Inducible gene deletion reveals different roles for B-Raf and Raf-1 in B-cell antigen receptor signalling. The EMBO journal\| PubMed ID: 12411479	2002
The adaptor protein SLP-65 acts as a tumor suppressor that limits pre-B cell expansion. Nature immunology\| PubMed ID: 12436112	2003
Hydrogen peroxide as second messenger in lymphocyte activation. Nature immunology\| PubMed ID: 12447370	2002
Amplification of B cell antigen receptor signaling by a Syk/ITAM positive feedback loop. Molecular cell\| PubMed ID: 12453414	2002
Activation of T cells via tumor antigen specific chimeric receptors: the role of the intracellular signaling domain. International journal of cancer\| PubMed ID: 12471624	2003
Essential role of Src-family protein tyrosine kinases in NF-kappaB activation during B cell development. Nature immunology\| PubMed ID: 12563261	2003
NF-kappaB is required for cell death induction by latent membrane protein 1 of Epstein-Barr virus. Cellular signalling\| PubMed ID: 12618217	2003
Genetic changes occurring in established tumors rapidly stimulate new antibody responses. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 12702750	2003
Deficiency of the adaptor SLP-65 in pre-B-cell acute lymphoblastic leukaemia. Nature\| PubMed ID: 12761551	2003
Establishment of immortalized human hepatic stellate scavenger cells to develop bioartificial livers. Transplantation\| PubMed ID: 12811248	2003
Bruton's tyrosine kinase cooperates with the B cell linker protein SLP-65 as a tumor suppressor in Pre-B cells. The Journal of experimental medicine\| PubMed ID: 12835482	2003
A high-molecular-weight complex of membrane proteins BAP29/BAP31 is involved in the retention of membrane-bound IgD in the endoplasmic reticulum. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 12886015	2003
Importance of TRF1 for functional telomere structure. The Journal of biological chemistry\| PubMed ID: 14559908	2004
B cell defects in SLP65/BLNK-deficient mice can be partially corrected by the absence of CD22, an inhibitory coreceptor for BCR signaling. European journal of immunology\| PubMed ID: 14635051	2003
Identification of a pre-BCR lacking surrogate light chain. The Journal of experimental medicine\| PubMed ID: 14638847	2003
Identification of novel ERK-mediated feedback phosphorylation sites at the C-terminus of B-Raf. Oncogene\| PubMed ID: 14654779	2003
Activation of the CKI-CDK-Rb-E2F pathway in full genome hepatitis C virus-expressing cells. The Journal of biological chemistry\| PubMed ID: 14747471	2004
A revised and complete map of the chicken c-mil/raf-1 locus. Oncogene\| PubMed ID: 14968114	2004
Feedback regulation of lymphocyte signalling. Nature reviews. Immunology\| PubMed ID: 15057785	2004
B cell antigen receptor assembly and Syk activation in the S2 cell reconstitution system. Immunology letters\| PubMed ID: 15081529	2004
Functional folding of a cytoplasmic single-chain variable fragment and its use as elutable protein purification tag. Immunology letters\| PubMed ID: 15081544	2004
B-cell signal transduction: tyrosine phosphorylation, kinase activity, and calcium mobilization. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 15146122	2004
Perspectives on the nature of BCR-mediated survival signals. Molecular cell\| PubMed ID: 15200948	2004
Adenosine and cAMP are potent inhibitors of the NF-kappa B pathway downstream of immunoreceptors. European journal of immunology\| PubMed ID: 15580656	2005
Reversible switching of immunoglobulin hypermutation machinery in a chicken B cell line. Biochemical and biophysical research communications\| PubMed ID: 15629431	2005
A leucine zipper in the N terminus confers membrane association to SLP-65. Nature immunology\| PubMed ID: 15654340	2005
Postnatal isl1+ cardioblasts enter fully differentiated cardiomyocyte lineages. Nature\| PubMed ID: 15703750	2005
B cell signaling and tumorigenesis. Annual review of immunology\| PubMed ID: 15771577	2005
Two dimensional Blue Native-/SDS-PAGE analysis of SLP family adaptor protein complexes. Immunology letters\| PubMed ID: 16356554	2006
Human T-cell leukemia virus type-I oncoprotein Tax inhibits Fas-mediated apoptosis by inducing cellular FLIP through activation of NF-kappaB. Genes to cells : devoted to molecular & cellular mechanisms\| PubMed ID: 16436054	2006
Canonical NF-kappaB activity, dispensable for B cell development, replaces BAFF-receptor signals and promotes B cell proliferation upon activation. Immunity\| PubMed ID: 16782029	2006
Identification of disulfide bonds in the Ig-alpha/Ig-beta component of the B cell antigen receptor using the Drosophila S2 cell reconstitution system. International immunology\| PubMed ID: 16877534	2006
Association of protein kinase C-delta with the B cell antigen receptor complex. Cellular signalling\| PubMed ID: 17098397	2007
Survival of liver failure pigs by transplantation of reversibly immortalized human hepatocytes with Tamoxifen-mediated self-recombination. Journal of hepatology\| PubMed ID: 17434229	2007
Yin Yang 1 is a critical regulator of B-cell development. Genes & development\| PubMed ID: 17504937	2007
Immunoreceptors and integrins. Immunological reviews\| PubMed ID: 17624940	2007
Mutations of the Igbeta gene cause agammaglobulinemia in man. The Journal of experimental medicine\| PubMed ID: 17709424	2007
The TCR binding site does move. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 17925433	2007
The kinase Syk as an adaptor controlling sustained calcium signalling and B-cell development. The EMBO journal\| PubMed ID: 18369315	2008
SLP-65 regulates immunoglobulin light chain gene recombination through the PI(3)K-PKB-Foxo pathway. Nature immunology\| PubMed ID: 18488031	2008
Functional analysis of histone methyltransferase g9a in B and T lymphocytes. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 18566414	2008
Enhanced B-cell activation mediated by TLR4 and BCR crosstalk. European journal of immunology\| PubMed ID: 18819072	2008
Clustering models. Advances in experimental medicine and biology\| PubMed ID: 19065784	2008
Genomic instability resulting from Blm deficiency compromises development, maintenance, and function of the B cell lineage. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 19109166	2009
Regulation of B-cell proliferation and differentiation by pre-B-cell receptor signalling. Nature reviews. Immunology\| PubMed ID: 19240758	2009
Molecular components of the B-cell antigen receptor complex of the IgM class. 1990. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 19620316	2009
Induction of B-cell development in adult mice reveals the ability of bone marrow to produce B-1a cells. Blood\| PubMed ID: 19812384	2009
Autoinhibition and adapter function of Syk. Immunological reviews\| PubMed ID: 19909371	2009
Analysis of novel phospho-ITAM specific antibodies in a S2 reconstitution system for TCR-CD3 signalling. Immunology letters\| PubMed ID: 20005895	2010
Voltage control for B cell activation. Nature immunology\| PubMed ID: 20157299	2010
Arginine methylation of the B cell antigen receptor promotes differentiation. The Journal of experimental medicine\| PubMed ID: 20231378	2010
N-linked glycosylation selectively regulates autonomous precursor BCR function. Nature immunology\| PubMed ID: 20622883	2010
Oligomeric organization of the B-cell antigen receptor on resting cells. Nature\| PubMed ID: 20818374	2010
The dissociation activation model of B cell antigen receptor triggering. FEBS letters\| PubMed ID: 20920502	2010
Syk is a dual-specificity kinase that self-regulates the signal output from the B-cell antigen receptor. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 20940318	2010
B cell homeostasis and plasma cell homing controlled by Krüppel-like factor 2. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 21187409	2011
B cells that produce immunoglobulin E mediate colitis in BALB/c mice. Gastroenterology\| PubMed ID: 21983080	2012
Bacillus subtilis MreB orthologs self-organize into filamentous structures underneath the cell membrane in a heterologous cell system. PloS one\| PubMed ID: 22069484	2011
Drosophila S2 Schneider cells: a useful tool for rebuilding and redesigning approaches in synthetic biology. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 22083752	2012
The SH2-domain of SHIP1 interacts with the SHIP1 C-terminus: impact on SHIP1/Ig-α interaction. Biochimica et biophysica acta\| PubMed ID: 22182704	2012
The E3 ubiquitin ligase Mule acts through the ATM-p53 axis to maintain B lymphocyte homeostasis. The Journal of experimental medicine\| PubMed ID: 22213803	2012
Synthetic immune signaling. Current opinion in biotechnology\| PubMed ID: 22326912	2012
Non-cell-autonomous hedgehog signaling promotes murine B lymphopoiesis from hematopoietic progenitors. Blood\| PubMed ID: 22517907	2012
Immunoglobulins drive terminal maturation of splenic dendritic cells. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 23345431	2013
Semi-supervised prediction of SH2-peptide interactions from imbalanced high-throughput data. PloS one\| PubMed ID: 23690949	2013
CD22 ligand-binding and signaling domains reciprocally regulate B-cell Ca2+ signaling. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 23836650	2013
Matching cellular dimensions with molecular sizes. Nature immunology\| PubMed ID: 23867923	2013
The serine/threonine phosphatase PP4 is required for pro-B cell development through its promotion of immunoglobulin VDJ recombination. PloS one\| PubMed ID: 23874770	2013
Inhibition of mTORC1 by astrin and stress granules prevents apoptosis in cancer cells. Cell\| PubMed ID: 23953116	2013
Proximity ligation assay for high-content profiling of cell signaling pathways on a microfluidic chip. Molecular & cellular proteomics : MCP\| PubMed ID: 24072685	2013
Pre-clustering of the B cell antigen receptor demonstrated by mathematically extended electron microscopy. Frontiers in immunology\| PubMed ID: 24367367	2013
Michael Neuberger (1953-2013). Immunity\| PubMed ID: 24479157	2013
Signaling circuits in early B-cell development. Advances in immunology\| PubMed ID: 24507157	2014
The protein tyrosine phosphatase PTP1B is a negative regulator of CD40 and BAFF-R signaling and controls B cell autoimmunity. The Journal of experimental medicine\| PubMed ID: 24590766	2014
Pillars article: antigen receptor tail clue. Nature. 1989. 338: 383-384. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 24748635	2014
MIF promotes B cell chemotaxis through the receptors CXCR4 and CD74 and ZAP-70 signaling. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 24760155	2014
The ligand-binding domain of Siglec-G is crucial for its selective inhibitory function on B1 cells. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 24790146	2014
The role of the Syk/Shp-1 kinase-phosphatase equilibrium in B cell development and signaling. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 24899508	2014
B cell activation involves nanoscale receptor reorganizations and inside-out signaling by Syk. eLife\| PubMed ID: 24963139	2014
PDK1 regulates B cell differentiation and homeostasis. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 24979759	2014
Production of IgG autoantibody requires expression of activation-induced deaminase in early-developing B cells in a mouse model of SLE. European journal of immunology\| PubMed ID: 25044405	2014
The AP-1 transcription factor Fra1 inhibits follicular B cell differentiation into plasma cells. The Journal of experimental medicine\| PubMed ID: 25288397	2014
Suboptimal B-cell antigen receptor signaling activity in vivo elicits germinal center counterselection mechanisms. European journal of immunology\| PubMed ID: 25382621	2015
The nanoscale organization of the B lymphocyte membrane. Biochimica et biophysica acta\| PubMed ID: 25450974	2015
CD19 and BAFF-R can signal to promote B-cell survival in the absence of Syk. The EMBO journal\| PubMed ID: 25630702	2015
Preface to special issue on nanoscale membrane organisations. Biochimica et biophysica acta\| PubMed ID: 25677899	2015
Fundamental properties of unperturbed haematopoiesis from stem cells in vivo. Nature\| PubMed ID: 25686605	2015
TSC1 activates TGF-β-Smad2/3 signaling in growth arrest and epithelial-to-mesenchymal transition. Developmental cell\| PubMed ID: 25727005	2015
Signalling thresholds and negative B-cell selection in acute lymphoblastic leukaemia. Nature\| PubMed ID: 25799995	2015
Responsiveness of B cells is regulated by the hinge region of IgD. Nature immunology\| PubMed ID: 25848865	2015
Erratum: Responsiveness of B cells is regulated by the hinge region of IgD. Nature immunology\| PubMed ID: 26086144	2015
Processing of CD74 by the Intramembrane Protease SPPL2a Is Critical for B Cell Receptor Signaling in Transitional B Cells. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 26157172	2015
Kidins220/ARMS binds to the B cell antigen receptor and regulates B cell development and activation. The Journal of experimental medicine\| PubMed ID: 26324445	2015
B cell antigen receptors of the IgM and IgD classes are clustered in different protein islands that are altered during B cell activation. Science signaling\| PubMed ID: 26373673	2015
Receptor Dissociation and B-Cell Activation. Current topics in microbiology and immunology\| PubMed ID: 26428245	2016
Survival of Igα-Deficient Mature B Cells Requires BAFF-R Function. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 26843325	2016
Corrigendum: Signalling thresholds and negative B-cell selection in acute lymphoblastic leukaemia. Nature\| PubMed ID: 26958840	2016
Molecular requirements of the B-cell antigen receptor for sensing monovalent antigens. The EMBO journal\| PubMed ID: 27634959	2016
What goes up must come down: A tripartite Dok-3/Grb2/SHIP1 inhibitory module limits BCR signaling. European journal of immunology\| PubMed ID: 27813071	2016