Michael Reth

Cre recombinase-controlled expression of the mb-1 allele.

The procaspase-8 isoform, procaspase-8L, recruited to the BAP31 complex at the endoplasmic reticulum.

The role of SHIP in mast cell degranulation and IgE-induced mast cell survival.

B cell progenitors are arrested in maturation but have intact VDJ recombination in the absence of Ig-alpha and Ig-beta.

BCR mutants deficient in ligand-independent and more sensitive for ligand-dependent signaling.

Inducible gene deletion reveals different roles for B-Raf and Raf-1 in B-cell antigen receptor signalling.

The adaptor protein SLP-65 acts as a tumor suppressor that limits pre-B cell expansion.

Hydrogen peroxide as second messenger in lymphocyte activation.

Amplification of B cell antigen receptor signaling by a Syk/ITAM positive feedback loop.

Activation of T cells via tumor antigen specific chimeric receptors: the role of the intracellular signaling domain.

Essential role of Src-family protein tyrosine kinases in NF-kappaB activation during B cell development.

NF-kappaB is required for cell death induction by latent membrane protein 1 of Epstein-Barr virus.

Genetic changes occurring in established tumors rapidly stimulate new antibody responses.

Deficiency of the adaptor SLP-65 in pre-B-cell acute lymphoblastic leukaemia.

Establishment of immortalized human hepatic stellate scavenger cells to develop bioartificial livers.

Bruton's tyrosine kinase cooperates with the B cell linker protein SLP-65 as a tumor suppressor in Pre-B cells.

A high-molecular-weight complex of membrane proteins BAP29/BAP31 is involved in the retention of membrane-bound IgD in the endoplasmic reticulum.

Importance of TRF1 for functional telomere structure.

B cell defects in SLP65/BLNK-deficient mice can be partially corrected by the absence of CD22, an inhibitory coreceptor for BCR signaling.

Identification of a pre-BCR lacking surrogate light chain.

Identification of novel ERK-mediated feedback phosphorylation sites at the C-terminus of B-Raf.

Activation of the CKI-CDK-Rb-E2F pathway in full genome hepatitis C virus-expressing cells.

A revised and complete map of the chicken c-mil/raf-1 locus.

Feedback regulation of lymphocyte signalling.

B cell antigen receptor assembly and Syk activation in the S2 cell reconstitution system.

Functional folding of a cytoplasmic single-chain variable fragment and its use as elutable protein purification tag.

B-cell signal transduction: tyrosine phosphorylation, kinase activity, and calcium mobilization.

Perspectives on the nature of BCR-mediated survival signals.

Adenosine and cAMP are potent inhibitors of the NF-kappa B pathway downstream of immunoreceptors.

Reversible switching of immunoglobulin hypermutation machinery in a chicken B cell line.

A leucine zipper in the N terminus confers membrane association to SLP-65.

Postnatal isl1+ cardioblasts enter fully differentiated cardiomyocyte lineages.

B cell signaling and tumorigenesis.

Two dimensional Blue Native-/SDS-PAGE analysis of SLP family adaptor protein complexes.

Human T-cell leukemia virus type-I oncoprotein Tax inhibits Fas-mediated apoptosis by inducing cellular FLIP through activation of NF-kappaB.

Canonical NF-kappaB activity, dispensable for B cell development, replaces BAFF-receptor signals and promotes B cell proliferation upon activation.

Identification of disulfide bonds in the Ig-alpha/Ig-beta component of the B cell antigen receptor using the Drosophila S2 cell reconstitution system.

Association of protein kinase C-delta with the B cell antigen receptor complex.

Survival of liver failure pigs by transplantation of reversibly immortalized human hepatocytes with Tamoxifen-mediated self-recombination.

Yin Yang 1 is a critical regulator of B-cell development.

Immunoreceptors and integrins.

Mutations of the Igbeta gene cause agammaglobulinemia in man.

The TCR binding site does move.

The kinase Syk as an adaptor controlling sustained calcium signalling and B-cell development.

SLP-65 regulates immunoglobulin light chain gene recombination through the PI(3)K-PKB-Foxo pathway.

Functional analysis of histone methyltransferase g9a in B and T lymphocytes.

Enhanced B-cell activation mediated by TLR4 and BCR crosstalk.

Clustering models.

Genomic instability resulting from Blm deficiency compromises development, maintenance, and function of the B cell lineage.

Regulation of B-cell proliferation and differentiation by pre-B-cell receptor signalling.

Molecular components of the B-cell antigen receptor complex of the IgM class. 1990.

Induction of B-cell development in adult mice reveals the ability of bone marrow to produce B-1a cells.

Autoinhibition and adapter function of Syk.

Analysis of novel phospho-ITAM specific antibodies in a S2 reconstitution system for TCR-CD3 signalling.

Voltage control for B cell activation.

Arginine methylation of the B cell antigen receptor promotes differentiation.

N-linked glycosylation selectively regulates autonomous precursor BCR function.

Oligomeric organization of the B-cell antigen receptor on resting cells.

The dissociation activation model of B cell antigen receptor triggering.

Syk is a dual-specificity kinase that self-regulates the signal output from the B-cell antigen receptor.

B cell homeostasis and plasma cell homing controlled by Krüppel-like factor 2.

B cells that produce immunoglobulin E mediate colitis in BALB/c mice.

Bacillus subtilis MreB orthologs self-organize into filamentous structures underneath the cell membrane in a heterologous cell system.

Drosophila S2 Schneider cells: a useful tool for rebuilding and redesigning approaches in synthetic biology.

The SH2-domain of SHIP1 interacts with the SHIP1 C-terminus: impact on SHIP1/Ig-α interaction.

The E3 ubiquitin ligase Mule acts through the ATM-p53 axis to maintain B lymphocyte homeostasis.

Synthetic immune signaling.

Non-cell-autonomous hedgehog signaling promotes murine B lymphopoiesis from hematopoietic progenitors.

Immunoglobulins drive terminal maturation of splenic dendritic cells.

Semi-supervised prediction of SH2-peptide interactions from imbalanced high-throughput data.

CD22 ligand-binding and signaling domains reciprocally regulate B-cell Ca2+ signaling.

Matching cellular dimensions with molecular sizes.

The serine/threonine phosphatase PP4 is required for pro-B cell development through its promotion of immunoglobulin VDJ recombination.

Inhibition of mTORC1 by astrin and stress granules prevents apoptosis in cancer cells.

Proximity ligation assay for high-content profiling of cell signaling pathways on a microfluidic chip.

Pre-clustering of the B cell antigen receptor demonstrated by mathematically extended electron microscopy.

Michael Neuberger (1953-2013).

Signaling circuits in early B-cell development.

The protein tyrosine phosphatase PTP1B is a negative regulator of CD40 and BAFF-R signaling and controls B cell autoimmunity.

Pillars article: antigen receptor tail clue. Nature. 1989. 338: 383-384.

MIF promotes B cell chemotaxis through the receptors CXCR4 and CD74 and ZAP-70 signaling.

The ligand-binding domain of Siglec-G is crucial for its selective inhibitory function on B1 cells.

The role of the Syk/Shp-1 kinase-phosphatase equilibrium in B cell development and signaling.

B cell activation involves nanoscale receptor reorganizations and inside-out signaling by Syk.

PDK1 regulates B cell differentiation and homeostasis.

Production of IgG autoantibody requires expression of activation-induced deaminase in early-developing B cells in a mouse model of SLE.

The AP-1 transcription factor Fra1 inhibits follicular B cell differentiation into plasma cells.

Suboptimal B-cell antigen receptor signaling activity in vivo elicits germinal center counterselection mechanisms.

The nanoscale organization of the B lymphocyte membrane.

CD19 and BAFF-R can signal to promote B-cell survival in the absence of Syk.

Preface to special issue on nanoscale membrane organisations.

Fundamental properties of unperturbed haematopoiesis from stem cells in vivo.

TSC1 activates TGF-β-Smad2/3 signaling in growth arrest and epithelial-to-mesenchymal transition.

Signalling thresholds and negative B-cell selection in acute lymphoblastic leukaemia.

Responsiveness of B cells is regulated by the hinge region of IgD.

Erratum: Responsiveness of B cells is regulated by the hinge region of IgD.

Processing of CD74 by the Intramembrane Protease SPPL2a Is Critical for B Cell Receptor Signaling in Transitional B Cells.

Kidins220/ARMS binds to the B cell antigen receptor and regulates B cell development and activation.

B cell antigen receptors of the IgM and IgD classes are clustered in different protein islands that are altered during B cell activation.

Receptor Dissociation and B-Cell Activation.

Survival of Igα-Deficient Mature B Cells Requires BAFF-R Function.

Corrigendum: Signalling thresholds and negative B-cell selection in acute lymphoblastic leukaemia.

Molecular requirements of the B-cell antigen receptor for sensing monovalent antigens.

What goes up must come down: A tripartite Dok-3/Grb2/SHIP1 inhibitory module limits BCR signaling.