Carole Guillonneau

Prolonged blockade of CD40-CD40 ligand interactions by gene transfer of CD40Ig results in long-term heart allograft survival and donor-specific hyporesponsiveness, but does not prevent chronic rejection.

Active suppression of allogeneic proliferative responses by dendritic cells after induction of long-term allograft survival by CTLA4Ig.

The role of TNF-related activation-induced cytokine-receptor activating NF-kappa B interaction in acute allograft rejection and CD40L-independent chronic allograft rejection.

Application of gene transfer technologies to transplantation.

Long term transgene expression by hepatocytes transduced with retroviral vectors requires induction of immune tolerance to the transgene.

Donor-specific allograft tolerance by administration of recipient-derived immature dendritic cells and suboptimal immunosuppression.

Inhibition of chronic rejection and development of tolerogenic T cells after ICOS-ICOSL and CD40-CD40L co-stimulation blockade.

Identification of a new member of the CD20/FcepsilonRIbeta family overexpressed in tolerated allografts.

Inhibition of chronic rejection and development of tolerogenic T cells after ICOS-ICOSL and CD40-CD40L co-stimulation blockade.

Accumulation of T cells with potent regulatory properties and restricted Vbeta7-TCR rearrangements in tolerated allografts.

Fms-like tyrosine kinase 3 ligand recruits plasmacytoid dendritic cells to the brain.

CD40Ig treatment results in allograft acceptance mediated by CD8CD45RC T cells, IFN-gamma, and indoleamine 2,3-dioxygenase.

Cutting edge: Tissue-resident memory CTL down-regulate cytolytic molecule expression following virus clearance.

Anti-CD28 antibodies modify regulatory mechanisms and reinforce tolerance in CD40Ig-treated heart allograft recipients.

Killer T cells in influenza.

Frontiers in immunology research network--2008 International Conference.

Complete modification of TCR specificity and repertoire selection does not perturb a CD8+ T cell immunodominance hierarchy.

Combined NKT cell activation and influenza virus vaccination boosts memory CTL generation and protective immunity.

Diversity and clonotypic composition of influenza-specific CD8+ TCR repertoires remain unaltered in the absence of Aire.

Constraints within major histocompatibility complex class I restricted peptides: presentation and consequences for T-cell recognition.

Mechanism and localization of CD8 regulatory T cells in a heart transplant model of tolerance.

Protective efficacy of cross-reactive CD8+ T cells recognising mutant viral epitopes depends on peptide-MHC-I structural interactions and T cell activation threshold.

CD8+ regulatory T cells in solid organ transplantation.

Phenotypic and functional characterization of CD8(+) T regulatory cells.

T-cell receptor specificity of CD8(+) Tregs in allotransplantation.

Structural basis for enabling T-cell receptor diversity within biased virus-specific CD8+ T-cell responses.

Affinity thresholds for naive CD8+ CTL activation by peptides and engineered influenza A viruses.

Loss of anti-viral immunity by infection with a virus encoding a cross-reactive pathogenic epitope.

Preemptive priming readily overcomes structure-based mechanisms of virus escape.

MHC-derived allopeptide activates TCR-biased CD8+ Tregs and suppresses organ rejection.

[Key role of allopeptide-specific CD8(+) Tregs in transplantation].

Fibrinogen-like protein 2/fibroleukin induces long-term allograft survival in a rat model through regulatory B cells.

Efficacy of Myeloid Derived Suppressor Cells on Transplant Survival.

IL-34 is a Treg-specific cytokine and mediates transplant tolerance.

Compensatory Regulatory Networks between CD8 T, B, and Myeloid Cells in Organ Transplantation Tolerance.

Improved Analyses of CD8+ T Cell Specificities Using Multimers of Peptide MHC Complexes Coupled to DNA Barcodes.

Transient antibody targeting of CD45RC induces transplant tolerance and potent antigen-specific regulatory T cells.

Immunoregulatory properties of the cytokine IL-34.

Breakdown of Immune Tolerance in AIRE-Deficient Rats Induces a Severe Autoimmune Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy-like Autoimmune Disease.

Cross-Reactive Donor-Specific CD8 Tregs Efficiently Prevent Transplant Rejection.

AIRE deficiency, from preclinical models to human APECED disease.

Patients With Severe Multiple Sclerosis Exhibit Functionally Altered CD8 Regulatory T Cells.