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Brain Research Institute
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NFATc1 phosphorylation by DYRK1A increases its protein stability.
PloS one , 2017 | Pubmed ID: 28235034
Degradation of regulator of calcineurin 1 (RCAN1) is mediated by both chaperone-mediated autophagy and ubiquitin proteasome pathways.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology Oct, 2009 | Pubmed ID: 19509306
REST regulates DYRK1A transcription in a negative feedback loop.
The Journal of biological chemistry Mar, 2011 | Pubmed ID: 21252229
Hyper-activation of WNT/β-catenin signaling pathway mediates anti-tumor effects of histone deacetylase inhibitors in acute T lymphoblastic leukemia.
Leukemia & lymphoma Sep, 2012 | Pubmed ID: 22303878
Notch1 is required for hypoxia-induced proliferation, invasion and chemoresistance of T-cell acute lymphoblastic leukemia cells.
Journal of hematology & oncology Jan, 2013 | Pubmed ID: 23289374
Regulator of calcineurin 1 gene transcription is regulated by nuclear factor-kappaB.
Current Alzheimer research Feb, 2014 | Pubmed ID: 24359503
RCAN1 increases Aβ generation by promoting N-glycosylation via oligosaccharyltransferase.
Current Alzheimer research May, 2014 | Pubmed ID: 24720891
RCAN1 overexpression exacerbates calcium overloading-induced neuronal apoptosis.
PloS one , 2014 | Pubmed ID: 24751678
Tumor suppressor DYRK1A effects on proliferation and chemoresistance of AML cells by downregulating c-Myc.
PloS one , 2014 | Pubmed ID: 24901999
Novel agent nitidine chloride induces erythroid differentiation and apoptosis in CML cells through c-Myc-miRNAs axis.
PloS one , 2015 | Pubmed ID: 25647305
Dysferlinopathy: mitochondrial abnormalities in human skeletal muscle.
The International journal of neuroscience Jul, 2015 | Pubmed ID: 26000923
RE1 silencing transcription factor (REST) negatively regulates ALL1-fused from chromosome 1q (AF1q) gene transcription.
BMC molecular biology Sep, 2015 | Pubmed ID: 26341630
E3 Ligase SCFβTrCP-induced DYRK1A Protein Degradation Is Essential for Cell Cycle Progression in HEK293 Cells.
The Journal of biological chemistry Dec, 2016 | Pubmed ID: 27807027
The regulator of calcineurin 1 increases adenine nucleotide translocator 1 and leads to mitochondrial dysfunctions.
Journal of neurochemistry Jan, 2017 | Pubmed ID: 27861892
The regulator of calcineurin 1 (RCAN1) inhibits nuclear factor kappaB signaling pathway and suppresses human malignant glioma cells growth.
Oncotarget Feb, 2017 | Pubmed ID: 28061453
Transcription factor NF-kappa B represses ANT1 transcription and leads to mitochondrial dysfunctions.
Scientific reports Mar, 2017 | Pubmed ID: 28317877
Dual-specificity tyrosine-phosphorylation regulated kinase 1A Gene Transcription is regulated by Myocyte Enhancer Factor 2D.
Scientific reports Aug, 2017 | Pubmed ID: 28775333
Cleavage of potassium channel Kv2.1 by BACE2 reduces neuronal apoptosis.
Molecular psychiatry Apr, 2018 | Pubmed ID: 29703946
Qilu hospital of shandong university
Wei Li1,2,
Chen Zhang1,
Xiulian Sun3
1Department of Neurology, Qilu Hospital of Shandong University,
2Department of Neurology, Qingdao Municipal Hospital,
3Brain Research Institute, Qilu Hospital of Shandong University
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