Brain Research Institute
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NFATc1 phosphorylation by DYRK1A increases its protein stability.
PloS one , 2017 | Pubmed ID: 28235034
Degradation of regulator of calcineurin 1 (RCAN1) is mediated by both chaperone-mediated autophagy and ubiquitin proteasome pathways.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology Oct, 2009 | Pubmed ID: 19509306
REST regulates DYRK1A transcription in a negative feedback loop.
The Journal of biological chemistry Mar, 2011 | Pubmed ID: 21252229
Hyper-activation of WNT/β-catenin signaling pathway mediates anti-tumor effects of histone deacetylase inhibitors in acute T lymphoblastic leukemia.
Leukemia & lymphoma Sep, 2012 | Pubmed ID: 22303878
Notch1 is required for hypoxia-induced proliferation, invasion and chemoresistance of T-cell acute lymphoblastic leukemia cells.
Journal of hematology & oncology Jan, 2013 | Pubmed ID: 23289374
Regulator of calcineurin 1 gene transcription is regulated by nuclear factor-kappaB.
Current Alzheimer research Feb, 2014 | Pubmed ID: 24359503
RCAN1 increases Aβ generation by promoting N-glycosylation via oligosaccharyltransferase.
Current Alzheimer research May, 2014 | Pubmed ID: 24720891
RCAN1 overexpression exacerbates calcium overloading-induced neuronal apoptosis.
PloS one , 2014 | Pubmed ID: 24751678
Tumor suppressor DYRK1A effects on proliferation and chemoresistance of AML cells by downregulating c-Myc.
PloS one , 2014 | Pubmed ID: 24901999
Novel agent nitidine chloride induces erythroid differentiation and apoptosis in CML cells through c-Myc-miRNAs axis.
PloS one , 2015 | Pubmed ID: 25647305
Dysferlinopathy: mitochondrial abnormalities in human skeletal muscle.
The International journal of neuroscience Jul, 2015 | Pubmed ID: 26000923
RE1 silencing transcription factor (REST) negatively regulates ALL1-fused from chromosome 1q (AF1q) gene transcription.
BMC molecular biology Sep, 2015 | Pubmed ID: 26341630
E3 Ligase SCFβTrCP-induced DYRK1A Protein Degradation Is Essential for Cell Cycle Progression in HEK293 Cells.
The Journal of biological chemistry Dec, 2016 | Pubmed ID: 27807027
The regulator of calcineurin 1 increases adenine nucleotide translocator 1 and leads to mitochondrial dysfunctions.
Journal of neurochemistry Jan, 2017 | Pubmed ID: 27861892
The regulator of calcineurin 1 (RCAN1) inhibits nuclear factor kappaB signaling pathway and suppresses human malignant glioma cells growth.
Oncotarget Feb, 2017 | Pubmed ID: 28061453
Transcription factor NF-kappa B represses ANT1 transcription and leads to mitochondrial dysfunctions.
Scientific reports Mar, 2017 | Pubmed ID: 28317877
Dual-specificity tyrosine-phosphorylation regulated kinase 1A Gene Transcription is regulated by Myocyte Enhancer Factor 2D.
Scientific reports Aug, 2017 | Pubmed ID: 28775333
Cleavage of potassium channel Kv2.1 by BACE2 reduces neuronal apoptosis.
Molecular psychiatry Apr, 2018 | Pubmed ID: 29703946
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