Department of Functional Genomics and Cancer
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Synergistic transcriptional activation by TATA-binding protein and hTAFII28 requires specific amino acids of the hTAFII28 histone fold.
Molecular and cellular biology Jul, 1999 | Pubmed ID: 10373554
Human TAF(II)55 interacts with the vitamin D(3) and thyroid hormone receptors and with derivatives of the retinoid X receptor that have altered transactivation properties.
Molecular and cellular biology Aug, 1999 | Pubmed ID: 10409738
The human TFIID components TAF(II)135 and TAF(II)20 and the yeast SAGA components ADA1 and TAF(II)68 heterodimerize to form histone-like pairs.
Molecular and cellular biology Jan, 2000 | Pubmed ID: 10594036
Histone folds mediate selective heterodimerization of yeast TAF(II)25 with TFIID components yTAF(II)47 and yTAF(II)65 and with SAGA component ySPT7.
Molecular and cellular biology Mar, 2001 | Pubmed ID: 11238921
The TFIID components human TAF(II)140 and Drosophila BIP2 (TAF(II)155) are novel metazoan homologues of yeast TAF(II)47 containing a histone fold and a PHD finger.
Molecular and cellular biology Aug, 2001 | Pubmed ID: 11438666
Distinct functions of TBP and TLF/TRF2 during spermatogenesis: requirement of TLF for heterochromatic chromocenter formation in haploid round spermatids.
Development (Cambridge, England) Feb, 2002 | Pubmed ID: 11861477
Distinct mutations in yeast TAF(II)25 differentially affect the composition of TFIID and SAGA complexes as well as global gene expression patterns.
Molecular and cellular biology May, 2002 | Pubmed ID: 11940675
Functional analysis of the TFIID-specific yeast TAF4 (yTAF(II)48) reveals an unexpected organization of its histone-fold domain.
The Journal of biological chemistry Nov, 2002 | Pubmed ID: 12237303
Crystal structure of a subcomplex of human transcription factor TFIID formed by TATA binding protein-associated factors hTAF4 (hTAF(II)135) and hTAF12 (hTAF(II)20).
The Journal of biological chemistry Nov, 2002 | Pubmed ID: 12237304
RNA polymerase II transcription in murine cells lacking the TATA binding protein.
Science (New York, N.Y.) Nov, 2002 | Pubmed ID: 12411709
The intracellular localisation of TAF7L, a paralogue of transcription factor TFIID subunit TAF7, is developmentally regulated during male germ-cell differentiation.
Journal of cell science May, 2003 | Pubmed ID: 12665565
The genetics of TBP and TBP-related factors.
Trends in biochemical sciences Jul, 2003 | Pubmed ID: 12878007
[TBP, a universal transcription factor?].
Medecine sciences : M/S May, 2004 | Pubmed ID: 15190478
Testis-specific transcription mechanisms promoting male germ-cell differentiation.
Reproduction (Cambridge, England) Jul, 2004 | Pubmed ID: 15232059
Cell-specific nucleolar localization of TBP-related factor 2.
Molecular biology of the cell Oct, 2004 | Pubmed ID: 15269281
Polar nuclear localization of H1T2, a histone H1 variant, required for spermatid elongation and DNA condensation during spermiogenesis.
Proceedings of the National Academy of Sciences of the United States of America Feb, 2005 | Pubmed ID: 15710904
Proteolytic cleavage of ALF into alpha- and beta-subunits that form homologous and heterologous complexes with somatic TFIIA and TRF2 in male germ cells.
FEBS letters Jun, 2005 | Pubmed ID: 15927180
TAF4 inactivation in embryonic fibroblasts activates TGF beta signalling and autocrine growth.
The EMBO journal Aug, 2005 | Pubmed ID: 16015375
Preparation, isolation and characterization of stage-specific spermatogenic cells for cellular and molecular analysis.
Nature methods Dec, 2004 | Pubmed ID: 16144087
New insights into TAFs as regulators of cell cycle and signaling pathways.
Cell cycle (Georgetown, Tex.) Nov, 2005 | Pubmed ID: 16205117
The TFIID subunit TAF4 regulates keratinocyte proliferation and has cell-autonomous and non-cell-autonomous tumour suppressor activity in mouse epidermis.
Development (Cambridge, England) Aug, 2007 | Pubmed ID: 17626060
TIPT, a male germ cell-specific partner of TRF2, is chromatin-associated and interacts with HP1.
Cell cycle (Georgetown, Tex.) May, 2008 | Pubmed ID: 18418073
Specialization of the general transcriptional machinery in male germ cells.
Cell cycle (Georgetown, Tex.) Nov, 2008 | Pubmed ID: 19001848
Recent advances in understanding the structure and function of general transcription factor TFIID.
Cellular and molecular life sciences : CMLS Jul, 2009 | Pubmed ID: 19308322
Cell-specific interaction of retinoic acid receptors with target genes in mouse embryonic fibroblasts and embryonic stem cells.
Molecular and cellular biology Jan, 2010 | Pubmed ID: 19884340
Genome-wide analysis of POU3F2/BRN2 promoter occupancy in human melanoma cells reveals Kitl as a novel regulated target gene.
Pigment cell & melanoma research Jun, 2010 | Pubmed ID: 20337985
Cell-specific occupancy of an extended repertoire of CREM and CREB binding loci in male germ cells.
BMC genomics Sep, 2010 | Pubmed ID: 20920259
seqMINER: an integrated ChIP-seq data interpretation platform.
Nucleic acids research Mar, 2011 | Pubmed ID: 21177645
Transcription cofactors TRIM24, TRIM28, and TRIM33 associate to form regulatory complexes that suppress murine hepatocellular carcinoma.
Proceedings of the National Academy of Sciences of the United States of America May, 2011 | Pubmed ID: 21531907
Front seat and back seat drivers of melanoma metastasis.
Pigment cell & melanoma research Oct, 2011 | Pubmed ID: 21910852
Interconversion between active and inactive TATA-binding protein transcription complexes in the mouse genome.
Nucleic acids research Feb, 2012 | Pubmed ID: 22013162
The TIF1α-related TRIM cofactors couple chromatin modifications to transcriptional regulation, signaling and tumor suppression.
Transcription Sep-Oct, 2011 | Pubmed ID: 22231120
Retinoic acid receptors recognize the mouse genome through binding elements with diverse spacing and topology.
The Journal of biological chemistry Jul, 2012 | Pubmed ID: 22661711
Retinoic acid induces Sertoli cell paracrine signals for spermatogonia differentiation but cell autonomously drives spermatocyte meiosis.
Proceedings of the National Academy of Sciences of the United States of America Oct, 2012 | Pubmed ID: 23012458
Trim24-repressed VL30 retrotransposons regulate gene expression by producing noncoding RNA.
Nature structural & molecular biology Mar, 2013 | Pubmed ID: 23377542
MITF, the Janus transcription factor of melanoma.
Future oncology (London, England) Feb, 2013 | Pubmed ID: 23414473
Sumoylation at chromatin governs coordinated repression of a transcriptional program essential for cell growth and proliferation.
Genome research Oct, 2013 | Pubmed ID: 23893515
TAF4 inactivation reveals the 3 dimensional growth promoting activities of collagen 6A3.
PloS one , 2014 | Pubmed ID: 24498316
TAF4, a subunit of transcription factor II D, directs promoter occupancy of nuclear receptor HNF4A during post-natal hepatocyte differentiation.
eLife Sep, 2014 | Pubmed ID: 25209997
Structural basis of natural promoter recognition by the retinoid X nuclear receptor.
Scientific reports Feb, 2015 | Pubmed ID: 25645674
No evidence for generation of alternatively spliced isoforms from the mutated Trim24 allele lacking exon 4 in mouse liver.
Journal of hepatology Jul, 2015 | Pubmed ID: 25701693
Neuronal identity genes regulated by super-enhancers are preferentially down-regulated in the striatum of Huntington's disease mice.
Human molecular genetics Jun, 2015 | Pubmed ID: 25784504
Transcription factor MITF and remodeller BRG1 define chromatin organisation at regulatory elements in melanoma cells.
eLife Mar, 2015 | Pubmed ID: 25803486
A Brn2-Zic1 axis specifies the neuronal fate of retinoic-acid-treated embryonic stem cells.
Journal of cell science Jul, 2015 | Pubmed ID: 25991548
MITF is a critical regulator of the carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1) in malignant melanoma.
Pigment cell & melanoma research Nov, 2015 | Pubmed ID: 26301891
Retinoic Acid Receptors Control Spermatogonia Cell-Fate and Induce Expression of the SALL4A Transcription Factor.
PLoS genetics Oct, 2015 | Pubmed ID: 26427057
Chromatin-Remodelling Complex NURF Is Essential for Differentiation of Adult Melanocyte Stem Cells.
PLoS genetics Oct, 2015 | Pubmed ID: 26440048
MITF and c-Jun antagonism interconnects melanoma dedifferentiation with pro-inflammatory cytokine responsiveness and myeloid cell recruitment.
Nature communications Nov, 2015 | Pubmed ID: 26530832
TRIM33 switches off Ifnb1 gene transcription during the late phase of macrophage activation.
Nature communications Nov, 2015 | Pubmed ID: 26592194
T-cell-intrinsic Tif1α/Trim24 regulates IL-1R expression on TH2 cells and TH2 cell-mediated airway allergy.
Proceedings of the National Academy of Sciences of the United States of America Feb, 2016 | Pubmed ID: 26787865
Melanoma addiction to the long non-coding RNA SAMMSON.
Nature Mar, 2016 | Pubmed ID: 27008969
Essential role of the TFIID subunit TAF4 in murine embryogenesis and embryonic stem cell differentiation.
Nature communications Mar, 2016 | Pubmed ID: 27026076
TRF2 is recruited to the pre-initiation complex as a testis-specific subunit of TFIIA/ALF to promote haploid cell gene expression.
Scientific reports Aug, 2016 | Pubmed ID: 27576952
Macrophage production and activation are dependent on TRIM33.
Oncotarget Jan, 2017 | Pubmed ID: 27974684
TEAD transcription factors are required for normal primary myoblast differentiation in vitro and muscle regeneration in vivo.
PLoS genetics Feb, 2017 | Pubmed ID: 28178271
Hypomorphic Pathogenic Variants in TAF13 Are Associated with Autosomal-Recessive Intellectual Disability and Microcephaly.
American journal of human genetics Mar, 2017 | Pubmed ID: 28257693
Selective elimination of long INterspersed element-1 expressing tumour cells by targeted expression of the HSV-TK suicide gene.
Oncotarget Jun, 2017 | Pubmed ID: 28415677
MITF-high and MITF-low cells and a novel subpopulation expressing genes of both cell states contribute to intra and inter-tumoral heterogeneity of primary melanoma.
Clinical cancer research : an official journal of the American Association for Cancer Research Aug, 2017 | Pubmed ID: 28855355
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