Ron Weiss

Design and connection of robust genetic circuits.

Automatic compilation from high-level biologically-oriented programming language to genetic regulatory networks.

Understanding signaling dynamics through synthesis.

Foundations for the design and implementation of synthetic genetic circuits.

Modular design of artificial tissue homeostasis: robust control through synthetic cellular heterogeneity.

Formation and optogenetic control of engineered 3D skeletal muscle bioactuators.

Genetically programmable pathogen sense and destroy.

Rapid, modular and reliable construction of complex mammalian gene circuits.

Microbead-based biomimetic synthetic neighbors enhance survival and function of rat pancreatic β-cells.

Realizing the potential of synthetic biology.

CRISPR transcriptional repression devices and layered circuits in mammalian cells.

Systematic transfer of prokaryotic sensors and circuits to mammalian cells.

Accurate predictions of genetic circuit behavior from part characterization and modular composition.

A platform for rapid prototyping of synthetic gene networks in mammalian cells.

Rapid neurogenesis through transcriptional activation in human stem cells.

A load driver device for engineering modularity in biological networks.

Modular construction of mammalian gene circuits using TALE transcriptional repressors.

Highly efficient Cas9-mediated transcriptional programming.

Mammalian synthetic circuits with RNA binding proteins for RNA-only delivery.

Isocost Lines Describe the Cellular Economy of Genetic Circuits.

Preserved DNA Damage Checkpoint Pathway Protects against Complications in Long-Standing Type 1 Diabetes.

SYNTHETIC BIOLOGY. Synthetic communities, the sum of parts.

N(1)-methylpseudouridine-incorporated mRNA outperforms pseudouridine-incorporated mRNA by providing enhanced protein expression and reduced immunogenicity in mammalian cell lines and mice.

Cas9 gRNA engineering for genome editing, activation and repression.

Genetically engineering self-organization of human pluripotent stem cells into a liver bud-like tissue using Gata6.

Synthetic Morphogenesis.

A novel Bxb1 integrase RMCE system for high fidelity site-specific integration of mAb expression cassette in CHO Cells.

Open-source, community-driven microfluidics with Metafluidics.

A Modular Approach to Building Complex Synthetic Circuits.

Programming gene and engineered-cell therapies with synthetic biology.

A multi-landing pad DNA integration platform for mammalian cell engineering.

Engineering modular intracellular protein sensor-actuator devices.

Stochastic Turing patterns in a synthetic bacterial population.

A mixed antagonistic/synergistic miRNA repression model enables accurate predictions of multi-input miRNA sensor activity.

Small-molecule-based regulation of RNA-delivered circuits in mammalian cells.

Engineering protein-protein devices for multilayered regulation of mRNA translation using orthogonal proteases in mammalian cells.

Author Correction: A mixed antagonistic/synergistic miRNA repression model enables accurate predictions of multi-input miRNA sensor activity.

Comparison of Integrases Identifies Bxb1-GA Mutant as the Most Efficient Site-Specific Integrase System in Mammalian Cells.

Dissecting N-Glycosylation Dynamics in Chinese Hamster Ovary Cells Fed-batch Cultures using Time Course Omics Analyses.

In vitro evolution of enhanced RNA replicons for immunotherapy.

Perspective: The promise of multi-cellular engineered living systems.

Small-molecule control of antibody N-glycosylation in engineered mammalian cells.

A high-throughput screening and computation platform for identifying synthetic promoters with enhanced cell-state specificity (SPECS).

A 'poly-transfection' method for rapid, one-pot characterization and optimization of genetic systems.

Immunogenicity of RNA Replicons Encoding HIV Env Immunogens Designed for Self-Assembly into Nanoparticles.

An Artificial Tissue Homeostasis Circuit Designed via Analog Circuit Techniques.

3D aggregation of cells in packed microgel media.

Correction: 3D aggregation of cells in packed microgel media.

Principles of synthetic biology: a MOOC for an emerging field.

An endoribonuclease-based feedforward controller for decoupling resource-limited genetic modules in mammalian cells.

In Vivo Validation of a Reversible Small Molecule-Based Switch for Synthetic Self-Amplifying mRNA Regulation.

Rethinking organoid technology through bioengineering.

TASBE Image Analytics: A Processing Pipeline for Quantifying Cell Organization from Fluorescent Microscopy.

Context-aware synthetic biology by controller design: Engineering the mammalian cell.

An engineered protein-phosphorylation toggle network with implications for endogenous network discovery.

Quantitative characterization of recombinase-based digitizer circuits enables predictable amplification of biological signals.

Multifunctional oncolytic nanoparticles deliver self-replicating IL-12 RNA to eliminate established tumors and prime systemic immunity.

Meeting Measurement Precision Requirements for Effective Engineering of Genetic Regulatory Networks.

Principles for the design of multicellular engineered living systems.

Robust and tunable signal processing in mammalian cells via engineered covalent modification cycles.

PERSIST platform provides programmable RNA regulation using CRISPR endoRNases.

Synthetic neuromorphic computing in living cells.

A synthetic transcription platform for programmable gene expression in mammalian cells.

The sound of silence: Transgene silencing in mammalian cell engineering.

Synthetic genetic circuits to uncover and enforce the OCT4 trajectories of successful reprogramming of human fibroblasts.

Cholesterol-Amino-Phosphate (CAP) Derived Lipid Nanoparticles for Delivery of Self-Amplifying RNA and Restoration of Spermatogenesis in Infertile Mice.