Ashley M. Buckle

MUSTANG-MR structural sieving server: applications in protein structural analysis and crystallography.

CLIMS: crystallography laboratory information management system.

PFD: a database for the investigation of protein folding kinetics and stability.

The high resolution crystal structure of the human tumor suppressor maspin reveals a novel conformational switch in the G-helix.

The 2.1A crystal structure of the far-red fluorescent protein HcRed: inherent conformational flexibility of the chromophore.

REFOLD: an analytical database of protein refolding methods.

Control of the coagulation system by serpins. Getting by with a little help from glycosaminoglycans.

T cell receptor recognition of a 'super-bulged' major histocompatibility complex class I-bound peptide.

Managing and mining protein crystallization data.

The REFOLD database: a tool for the optimization of protein expression and refolding.

An overview of the serpin superfamily.

X-ray crystal structure of MENT: evidence for functional loop-sheet polymers in chromatin condensation.

Protein Folding Database (PFD 2.0): an online environment for the International Foldeomics Consortium.

The 1.6 A crystal structure of the catalytic domain of PlyB, a bacteriophage lysin active against Bacillus anthracis.

GABA production by glutamic acid decarboxylase is regulated by a dynamic catalytic loop.

The N terminus of the serpin, tengpin, functions to trap the metastable native state.

A common fold mediates vertebrate defense and bacterial attack.

X-ray crystal structure of the fibrinolysis inhibitor alpha2-antiplasmin.

COOH-terminal clustering of autoantibody and T-cell determinants on the structure of GAD65 provide insights into the molecular basis of autoreactivity.

A structural basis for loop C-sheet polymerization in serpins.

The MACPF/CDC family of pore-forming toxins.

Federated repositories of X-ray diffraction images.

Structural basis for the inhibition of the essential Plasmodium falciparum M1 neutral aminopeptidase.

Structure of granzyme C reveals an unusual mechanism of protease autoinhibition.

Structural biology of the GAD autoantigen.

Prodepth: predict residue depth by support vector regression approach from protein sequences only.

Structural determinants of GAD antigenicity.

Structure of the Plasmodium falciparum M17 aminopeptidase and significance for the design of drugs targeting the neutral exopeptidases.

The X-ray crystal structure of Escherichia coli succinic semialdehyde dehydrogenase; structural insights into NADP+/enzyme interactions.

MrGrid: a portable grid based molecular replacement pipeline.

EGM: encapsulated gene-by-gene matching to identify gene orthologs and homologous segments in genomes.

Characterisation of peptide microarrays for studying antibody-antigen binding using surface plasmon resonance imagery.

PolyQ: a database describing the sequence and domain context of polyglutamine repeats in proteins.

An analysis of the cross-reactivity of autoantibodies to GAD65 and GAD67 in diabetes.

Crystallographic and molecular dynamics analysis of loop motions unmasking the peptidoglycan-binding site in stator protein MotB of flagellar motor.

Mastering the canonical loop of serine protease inhibitors: enhancing potency by optimising the internal hydrogen bond network.

Refolding your protein with a little help from REFOLD.

The rate of polyQ-mediated aggregation is dramatically affected by the number and location of surrounding domains.

Computational methods for studying serpin conformational change and structural plasticity.

Recombinant protein quality evaluation: proposal for a minimal information standard.

Epitope flexibility and dynamic footprint revealed by molecular dynamics of a pMHC-TCR complex.

Hybrid approaches to molecular simulation.

Conformational properties of the disease-causing Z variant of α1-antitrypsin revealed by theory and experiment.

Crystal, solution and in silico structural studies of dihydrodipicolinate synthase from the common grapevine.

X-ray crystal structure of the streptococcal specific phage lysin PlyC.

Structural characterization of the mechanism through which human glutamic acid decarboxylase auto-activates.

Molecular determinants of the substrate specificity of the complement-initiating protease, C1r.

A redundant role of human thyroid peroxidase propeptide for cellular, enzymatic, and immunological activity.

Membrane proteins of Pseudoalteromonas tunicata during the transition from planktonic to extracellular matrix-adherent state.

Interactive visualization tools for the structural biologist.

PLP-dependent enzymes.

The α-importome of mammalian germ cell maturation provides novel insights for importin biology.

Cofactor-dependent conformational heterogeneity of GAD65 and its role in autoimmunity and neurotransmitter homeostasis.

Oxidation of an Exposed Methionine Instigates the Aggregation of Glyceraldehyde-3-Phosphate Dehydrogenase.

Operation of the Australian Store.Synchrotron for macromolecular crystallography.

Understanding the structural dynamics of TCR-pMHC complex interactions.

Structural and dynamic properties that govern the stability of an engineered fibronectin type III domain.

Solution structure of a soluble fragment derived from a membrane protein by shotgun proteolysis.

Critical evaluation of in silico methods for prediction of coiled-coil domains in proteins.

Dynamic Motion and Communication in the Streptococcal C1 Phage Lysin, PlyC.

Modelling of Thyroid Peroxidase Reveals Insights into Its Enzyme Function and Autoantigenicity.

A colostrum trypsin inhibitor gene expressed in the Cape fur seal mammary gland during lactation.

PolyQ 2.0: an improved version of PolyQ, a database of human polyglutamine proteins.

KinetochoreDB: a comprehensive online resource for the kinetochore and its related proteins.

Consensus protein design.

Circumventing the stability-function trade-off in an engineered FN3 domain.

The role of protein dynamics in the evolution of new enzyme function.

Smoothing a rugged protein folding landscape by sequence-based redesign.

Direct and indirect mechanisms of KLK4 inhibition revealed by structure and dynamics.

Structural reconstruction of protein ancestry.

The Pu.1 target gene Zbtb11 regulates neutrophil development through its integrase-like HHCC zinc finger.

REFOLDdb: a new and sustainable gateway to experimental protocols for protein refolding.

Generation of AMBER force field parameters for zinc centres of M1 and M17 family aminopeptidases.

Laboratory evolution of protein conformational dynamics.

Recognition by host nuclear transport proteins drives disorder-to-order transition in Hendra virus V.

Previously Hidden Dynamics at the TCR-Peptide-MHC Interface Revealed.

Substrate Locking Promotes Dimer-Dimer Docking of an Enzyme Antibiotic Target.

Structural Capacitance in Protein Evolution and Human Diseases.

Catalytic diversity and cell wall binding repeats in the phage-encoded endolysins.

Mapping the Pathway and Dynamics of Bestatin Inhibition of the Plasmodium falciparum M1 Aminopeptidase PfA-M1.

Thyroid Peroxidase as an Autoantigen in Hashimoto's Disease: Structure, Function, and Antigenicity.

Prostate Cancer Risk-Associated Single-Nucleotide Polymorphism Affects Prostate-Specific Antigen Glycosylation and Its Function.

Integrating Experiment and Theory to Understand TCR-pMHC Dynamics.

Potent, multi-target serine protease inhibition achieved by a simplified β-sheet motif.

Reactive centre loop dynamics and serpin specificity.

Protein engineering: the potential of remote mutations.

KLK4 Inhibition by Cyclic and Acyclic Peptides: Structural and Dynamical Insights into Standard-Mechanism Protease Inhibitors.

Wavelength-Dependent Fluorescent Immunosensors via Incorporation of Polarity Indicators near the Binding Interface of Antibody Fragments.

The Role of Conformational Dynamics in Abacavir-Induced Hypersensitivity Syndrome.

Crystal structure of the inhibitor-free form of the serine protease kallikrein-4.

Denisovan, modern human and mouse TNFAIP3 alleles tune A20 phosphorylation and immunity.

Strategies for Increasing Protein Stability.

Ribosome Evolution and Structural Capacitance.

Structural Studies of Thyroid Peroxidase Show the Monomer Interacting With Autoantibodies in Thyroid Autoimmune Disease.

Development and Differentiation in Monobodies Based on the Fibronectin Type 3 Domain.

Intrinsic limitations in mainstream methods of identifying network motifs in biology.

Conformational diversity facilitates antibody mutation trajectories and discrimination between foreign and self-antigens.

Impact of HLA-DR Antigen Binding Cleft Rigidity on T Cell Recognition.

Mutational and biophysical robustness in a pre-stabilized monobody.

A Comprehensive Phylogenetic Analysis of the Serpin Superfamily.

High avidity drives the interaction between the streptococcal C1 phage endolysin, PlyC, with the cell surface carbohydrates of Group A Streptococcus.