Center for Integrative Biology
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Calcium release from intra-axonal endoplasmic reticulum leads to axon degeneration through mitochondrial dysfunction.
The Journal of neuroscience : the official journal of the Society for Neuroscience May, 2014 | Pubmed ID: 24849352
Altered potassium channel distribution and composition in myelinated axons suppresses hyperexcitability following injury.
eLife Apr, 2016 | Pubmed ID: 27033551
Injury to the nervous system: A look into the ER.
Brain research 10, 2016 | Pubmed ID: 27117870
Bursting the unfolded protein response accelerates axonal regeneration.
Neural regeneration research Jun, 2016 | Pubmed ID: 27482204
Origin of axonal proteins: Is the axon-schwann cell unit a functional syncytium?
Cytoskeleton (Hoboken, N.J.) Oct, 2016 | Pubmed ID: 27490284
Schwann Cell and Axon: An Interlaced Unit-From Action Potential to Phenotype Expression.
Advances in experimental medicine and biology , 2016 | Pubmed ID: 27714690
Herpes Simplex Virus Type 1 Neuronal Infection Perturbs Golgi Apparatus Integrity through Activation of Src Tyrosine Kinase and Dyn-2 GTPase.
Frontiers in cellular and infection microbiology , 2017 | Pubmed ID: 28879169
Axonal Degeneration during Aging and Its Functional Role in Neurodegenerative Disorders.
Frontiers in neuroscience , 2017 | Pubmed ID: 28928628
Disulfide cross-linked multimers of TDP-43 and spinal motoneuron loss in a TDP-43 ALS/FTD mouse model.
Scientific reports 10, 2017 | Pubmed ID: 29079747
Molecular analysis of axonal-intrinsic and glial-associated co-regulation of axon degeneration.
Cell death & disease 11, 2017 | Pubmed ID: 29120410
A dual role for Integrin α6β4 in modulating hereditary neuropathy with liability to pressure palsies.
Journal of neurochemistry 05, 2018 | Pubmed ID: 29315582
In Vitro Analysis of the Role of Schwann Cells on Axonal Degeneration and Regeneration Using Sensory Neurons from Dorsal Root Ganglia.
Methods in molecular biology (Clifton, N.J.) , 2018 | Pubmed ID: 29546712
Purification of Exosomes from Primary Schwann Cells, RNA Extraction, and Next-Generation Sequencing of Exosomal RNAs.
Methods in molecular biology (Clifton, N.J.) , 2018 | Pubmed ID: 29546715
Teased Fiber Preparation of Myelinated Nerve Fibers from Peripheral Nerves for Vital Dye Staining and Immunofluorescence Analysis.
Methods in molecular biology (Clifton, N.J.) , 2018 | Pubmed ID: 29546717
The inhibition of CTGF/CCN2 activity improves muscle and locomotor function in a murine ALS model.
Human molecular genetics 08, 2018 | Pubmed ID: 29860398
IRE1α governs cytoskeleton remodelling and cell migration through a direct interaction with filamin A.
Nature cell biology 08, 2018 | Pubmed ID: 30013108
Mitochondria and Calcium Regulation as Basis of Neurodegeneration Associated With Aging.
Frontiers in neuroscience , 2018 | Pubmed ID: 30057523
Publisher Correction: IRE1α governs cytoskeleton remodelling and cell migration through a direct interaction with filamin A.
Nature cell biology Oct, 2018 | Pubmed ID: 30089843
Axonal degeneration induced by glutamate excitotoxicity is mediated by necroptosis.
Journal of cell science 11, 2018 | Pubmed ID: 30333135
Axonal Degeneration Is Mediated by Necroptosis Activation.
The Journal of neuroscience : the official journal of the Society for Neuroscience 05, 2019 | Pubmed ID: 30850513
Compartmentalized necroptosis activation in excitotoxicity-induced axonal degeneration: a novel mechanism implicated in neurodegenerative disease pathology.
Neural regeneration research Aug, 2019 | Pubmed ID: 30964063
Non-canonical function of IRE1α determines mitochondria-associated endoplasmic reticulum composition to control calcium transfer and bioenergetics.
Nature cell biology 06, 2019 | Pubmed ID: 31110288
Altered mitochondrial bioenergetics are responsible for the delay in Wallerian degeneration observed in neonatal mice.
Neurobiology of disease 10, 2019 | Pubmed ID: 31176719
Publisher Correction: Non-canonical function of IRE1α determines mitochondria-associated endoplasmic reticulum composition to control calcium transfer and bioenergetics.
Nature cell biology Jul, 2019 | Pubmed ID: 31201389
The p75 neurotrophin receptor is required to organize the mature neuromuscular synapse by regulating synaptic vesicle availability.
Acta neuropathologica communications 09, 2019 | Pubmed ID: 31514753
The necroptosis machinery mediates axonal degeneration in a model of Parkinson disease.
Cell death and differentiation 04, 2020 | Pubmed ID: 31591470
Correction: The necroptosis machinery mediates axonal degeneration in a model of Parkinson disease.
Cell death and differentiation Jul, 2020 | Pubmed ID: 32047275
The necroptosis pathway and its role in age-related neurodegenerative diseases: will it open up new therapeutic avenues in the next decade?
Expert opinion on therapeutic targets 07, 2020 | Pubmed ID: 32310729
Schwann cell reprogramming into repair cells increases miRNA-21 expression in exosomes promoting axonal growth.
Journal of cell science 06, 2020 | Pubmed ID: 32409566
Ex Vivo Analysis of Axonal Degeneration Using Sciatic and Optic Nerve Preparations.
Methods in molecular biology (Clifton, N.J.) , 2020 | Pubmed ID: 32524481
Collateral Sprouting of Peripheral Sensory Neurons Exhibits a Unique Transcriptomic Profile.
Molecular neurobiology Oct, 2020 | Pubmed ID: 32696431
Axonal Degeneration in AD: The Contribution of Aβ and Tau.
Frontiers in aging neuroscience , 2020 | Pubmed ID: 33192476
GERO Cohort Protocol, Chile, 2017-2022: Community-based Cohort of Functional Decline in Subjective Cognitive Complaint elderly.
BMC geriatrics 11, 2020 | Pubmed ID: 33238908
New insights on the molecular mechanisms of collateral sprouting after peripheral nerve injury.
Neural regeneration research Sep, 2021 | Pubmed ID: 33510065
Dementia in Latin America: Paving the way toward a regional action plan.
Alzheimer's & dementia : the journal of the Alzheimer's Association 02, 2021 | Pubmed ID: 33634602
Author Correction: IRE1α governs cytoskeleton remodeling and cell migration through a direct interaction with filamin A.
Nature cell biology May, 2021 | Pubmed ID: 33907311
Enhanced Activity of Exportin-1/CRM1 in Neurons Contributes to Autophagy Dysfunction and Senescent Features in Old Mouse Brain.
Oxidative medicine and cellular longevity , 2021 | Pubmed ID: 34434486
Aβ oligomers trigger necroptosis-mediated neurodegeneration via microglia activation in Alzheimer's disease.
Acta neuropathologica communications 03, 2022 | Pubmed ID: 35264247
Commentary on "PANoptosis-like cell death in ischemia/reperfusion injury of retinal neurons".
Neural regeneration research Feb, 2023 | Pubmed ID: 35900426
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