Ran Zhuang

[Cloning, prokaryotic expression of LAIR and identification of their immunological reactivities].

[Changes and significance of TNF, sIL-2R, IL-6, IL-4 and IFN-gamma levels in plasma from the patients with hemorrhagic fever with renal syndrome].

[Apoptosis-inducing ligand TRAIL can be recruited to lipid rafts].

Expression pattern of epithelial cell adhesion molecule on normal and malignant colon tissues.

[Regulation of soluble TRAIL and membrane TRAIL in Jurkat cells by PMA].

[Preparation, purification and identification of the rabbit antibody against extracellular region of mLAIR-1].

Generation of monoclonal antibodies to cancer/testis (CT) antigen CT10/MAGE-C2.

Dynamic changes of apoptosis-inducing ligands and Th1/Th2 like subpopulations in Hantaan virus-induced hemorrhagic fever with renal syndrome.

[Preparation and characterization of monoclonal antibodies against human CD112 (Nectin2/PRR2)].

Purification of GFP fusion proteins with high purity and yield by monoclonal antibody-coupled affinity column chromatography.

Generation of monoclonal antibodies against Escherichia coli DsbA.

Application of sandwich ELISA for detecting tag fusion proteins in high throughput.

Expression of CD226 antagonizes apoptotic cell death in murine thymocytes.

Increased levels of soluble CD226 in sera accompanied by decreased membrane CD226 expression on peripheral blood mononuclear cells from cancer patients.

[Study on the effect of CD4+CD25+ regulatory T cell adoptive transfusion on humoral immune function in rat composite tissue allotransplantation model].

Cystatin C, a novel urinary biomarker for sensitive detection of acute kidney injury during haemorrhagic fever with renal syndrome.

miR-30c-1* promotes natural killer cell cytotoxicity against human hepatoma cells by targeting the transcription factor HMBOX1.

Establishment of reverse direct ELISA and its application in screening high-affinity monoclonal antibodies.

Identification of a novel B-cell epitope of Hantaan virus glycoprotein recognized by neutralizing 3D8 monoclonal antibody.

Plexin-B1: a potential diagnostic biomarker for glioma and a future target for glioma immunotherapy.

The genetic polymorphisms of HLA are strongly correlated with the disease severity after Hantaan virus infection in the Chinese Han population.

Sustained high level of serum VEGF at convalescent stage contributes to the renal recovery after HTNV infection in patients with hemorrhagic fever with renal syndrome.

Heterogeneous expression of CT10, CT45 and GAGE7 antigens and their prognostic significance in human breast carcinoma.

Interleukin-17 plays a critical role in the acute rejection of intestinal transplantation.

HLA-A2 and B35 restricted hantaan virus nucleoprotein CD8+ T-cell epitope-specific immune response correlates with milder disease in hemorrhagic fever with renal syndrome.

Expression of leukocyte-associated immunoglobulin-like receptor-1 (LAIR-1) on osteoclasts and its potential role in rheumatoid arthritis.

Elevated plasma soluble Sema4D/CD100 levels are associated with disease severity in patients of hemorrhagic fever with renal syndrome.

The role of LAIR-1 (CD305) in T cells and monocytes/macrophages in patients with rheumatoid arthritis.

Hantaan virus infection induces CXCL10 expression through TLR3, RIG-I, and MDA-5 pathways correlated with the disease severity.

Increased plasma cell-free DNA level during HTNV infection: correlation with disease severity and virus load.

UPR decreases CD226 ligand CD155 expression and sensitivity to NK cell-mediated cytotoxicity in hepatoma cells.

IL-33/ST2 correlates with severity of haemorrhagic fever with renal syndrome and regulates the inflammatory response in Hantaan virus-infected endothelial cells.

Soluble Scavenger Receptor CD163 Is Associated with Severe Acute Kidney Injury in Patients with Hantaan Virus Infection.

Hantaan virus infection induces both Th1 and ThGranzyme B+ cell immune responses that associated with viral control and clinical outcome in humans.

Elevated Plasma Soluble CD14 Levels Correlate with the Monocyte Response Status During Hantaan Virus Infection in Humans.

CD8low CD100- T Cells Identify a Novel CD8 T Cell Subset Associated with Viral Control during Human Hantaan Virus Infection.

COMP-Ang1 promotes long-term survival of allogeneic islet grafts in a bioinert perforated chamber by inhibiting inflammation via inhibition of the TLR4 signaling pathway.

CD226 reduces endothelial cell glucose uptake under hyperglycemic conditions with inflammation in type 2 diabetes mellitus.

Specially modified stromal and immune microenvironment in injected bone marrow following intrabone transplantation facilitates allogeneic hematopoietic stem cell engraftment.

Structure and Function of HLA-A*02-Restricted Hantaan Virus Cytotoxic T-Cell Epitope That Mediates Effective Protective Responses in HLA-A2.1/K(b) Transgenic Mice.

Sustained High Levels of Both Total and High Molecular Weight Adiponectin in Plasma during the Convalescent Phase of Haemorrhagic Fever with Renal Syndrome Are Associated with Disease Severity.

Elevated Plasma Growth Arrest-Specific 6 Protein Levels Are Associated with the Severity of Disease During Hantaan Virus Infection in Humans.

Novel Identified HLA-A*0201-Restricted Hantaan Virus Glycoprotein Cytotoxic T-Cell Epitopes Could Effectively Induce Protective Responses in HLA-A2.1/K Transgenic Mice May Associate with the Severity of Hemorrhagic Fever with Renal Syndrome.

Blocking CD226 Promotes Allogeneic Transplant Immune Tolerance and Improves Skin Graft Survival by Increasing the Frequency of Regulatory T Cells in a Murine Model.

Effects of CD100 promote wound healing in diabetic mice.

ADAR1 attenuates allogeneic graft rejection by suppressing miR-21 biogenesis in macrophages and promoting M2 polarization.

TIGIT-Fc alleviates acute graft-versus-host disease by suppressing CTL activation via promoting the generation of immunoregulatory dendritic cells.

Silencing LAIR-1 in human THP-1 macrophage increases foam cell formation by modulating PPARγ and M2 polarization.

CD226 is involved in megakaryocyte activation and early-stage differentiation.

[CD226 knockout aggravates radiation-induced liver injury in mice].

CD226 deficiency on regulatory T cells aggravates renal fibrosis via up-regulation of Th2 cytokines through miR-340.

ECDI-fixed donor splenocytes prolong skin allograft survival by promoting M2 macrophage polarization and inducing regulatory T cells.

Deficiency of platelet adhesion molecule CD226 causes megakaryocyte development and platelet hyperactivity.

ADAR1 Alleviates Inflammation in a Murine Sepsis Model via the ADAR1-miR-30a-SOCS3 Axis.

[The conditional knockout of CD226 gene reduces acute lung injury in mice with hemorrhagic shock].

[Exploration and practice of online teaching system of medical immunology based on small private online course (SPOC) model during coronavirus disease 2019 (COVID-19) pandemic].

LAIR-1 overexpression inhibits epithelial-mesenchymal transition in osteosarcoma via GLUT1-related energy metabolism.

Protective CD8 T-cell response against Hantaan virus infection induced by immunization with designed linear multi-epitope peptides in HLA-A2.1/K transgenic mice.

[Preparation and application of mouse-derived monoclonal antibodies against mouse CD226].

Splenectomy improves liver fibrosis via tumor necrosis factor superfamily 14 (LIGHT) through the JNK/TGF-β1 signaling pathway.

Silencing of HuR Inhibits Osteosarcoma Cell Epithelial-Mesenchymal Transition AGO2 in Association With Long Non-Coding RNA XIST.

Adiponectin's globular domain inhibits T cell activation by interacting with LAIR-1.

Elevated Plasma Fractalkine Level Is Associated with the Severity of Hemorrhagic Fever with Renal Syndrome in Humans.

GDF15 induces immunosuppression via CD48 on regulatory T cells in hepatocellular carcinoma.

CD226 Is Required to Maintain Megakaryocytes/Platelets Homeostasis in the Treatment of Knee Osteoarthritis With Platelet-Rich Plasma in Mice.

Platelet-mediated tumor metastasis mechanism and the role of cell adhesion molecules.

CD226 deficiency promotes glutaminolysis and alleviates mitochondria damage in vascular endothelial cells under hemorrhagic shock.

Acute Cold Water-Immersion Restraint Stress Induces Intestinal Injury and Reduces the Diversity of Gut Microbiota in Mice.

[Preparation and identification of mouse-derived monoclonal antibodies to human ST2 molecule].

CD226 knockout alleviates high-fat diet induced obesity by suppressing proinflammatory macrophage phenotype.

Interleukin-6 absence triggers intestinal microbiota dysbiosis and mucosal immunity in mice.