Darrell Kotton

Stem cell antigen-1 expression in the pulmonary vascular endothelium.

Side population cells and Bcrp1 expression in lung.

Lung stem cells: new paradigms.

Embryonic lung side population cells are hematopoietic and vascular precursors.

A novel stem-cell population in adult liver with potent hematopoietic-reconstitution activity.

Failure of bone marrow to reconstitute lung epithelium.

Lung stem cells.

The prolonged life-span of alveolar macrophages.

Another notch in stem cell biology: Drosophila intestinal stem cells and the specification of cell fates.

Sustained expression of alpha1-antitrypsin after transplantation of manipulated hematopoietic stem cells.

Induced pluripotent stem cell generation using a single lentiviral stem cell cassette.

Transcriptional analysis of fracture healing and the induction of embryonic stem cell-related genes.

Pulmonary alveolar proteinosis: a bench-to-bedside story of granulocyte-macrophage colony-stimulating factor dysfunction.

Excision of reprogramming transgenes improves the differentiation potential of iPS cells generated with a single excisable vector.

Epigenetic mechanisms modulate thyroid transcription factor 1-mediated transcription of the surfactant protein B gene.

Amelioration of emphysema in mice through lentiviral transduction of long-lived pulmonary alveolar macrophages.

miR-129 regulates cell proliferation by downregulating Cdk6 expression.

FOXO1 modulates osteoblast differentiation.

Telomere dysfunction induces metabolic and mitochondrial compromise.

Mouse ES and iPS cells can form similar definitive endoderm despite differences in imprinted genes.

A shift from cell cultures to creatures: in vivo imaging of small animals in experimental regenerative medicine.

Programmatic change: lung disease research in the era of induced pluripotency.

Role of Nanog in the maintenance of marrow stromal stem cells during post natal bone regeneration.

Maintenance and repair of the lung endothelium does not involve contributions from marrow-derived endothelial precursor cells.

Self-renewing endodermal progenitor lines generated from human pluripotent stem cells.

Efficient derivation of purified lung and thyroid progenitors from embryonic stem cells.

Next-generation regeneration: the hope and hype of lung stem cell research.

The Transcription Factors Grainyhead-like 2 and NK2-Homeobox 1 Form a Regulatory Loop That Coordinates Lung Epithelial Cell Morphogenesis and Differentiation.

The 2012 Nobel Prize in physiology or medicine: democratizing pluripotency for lung researchers.

Residual expression of reprogramming factors affects the transcriptional program and epigenetic signatures of induced pluripotent stem cells.

Lentiviral delivery of RNAi for in vivo lineage-specific modulation of gene expression in mouse lung macrophages.

Intracellular bacillary burden reflects a burst size for Mycobacterium tuberculosis in vivo.

Lectin-dependent enhancement of Ebola virus infection via soluble and transmembrane C-type lectin receptors.

The aryl hydrocarbon receptor directs hematopoietic progenitor cell expansion and differentiation.

Diffuse lung disease in children: summary of a scientific conference.

Diminished Memory T-Cell Expansion Due to Delayed Kinetics of Antigen Expression by Lentivectors.

Clonal genetic and hematopoietic heterogeneity among human-induced pluripotent stem cell lines.

Induced pluripotent stem cell modeling of multisystemic, hereditary transthyretin amyloidosis.

Modeling pulmonary alveolar proteinosis with induced pluripotent stem cells.

Derivation of Endodermal Progenitors From Pluripotent Stem Cells.

Induced pluripotent stem cells model personalized variations in liver disease resulting from α1-antitrypsin deficiency.

Emergence of a stage-dependent human liver disease signature with directed differentiation of alpha-1 antitrypsin-deficient iPS cells.

Regeneration of Thyroid Function by Transplantation of Differentiated Pluripotent Stem Cells.

Unstable neurons underlie a stable learned behavior.

Thyroid Progenitors Are Robustly Derived from Embryonic Stem Cells through Transient, Developmental Stage-Specific Overexpression of Nkx2-1.

Efficient Derivation of Functional Human Airway Epithelium from Pluripotent Stem Cells via Temporal Regulation of Wnt Signaling.

Capacity of Pneumococci to Activate Macrophage Nuclear Factor κB: Influence on Necroptosis and Pneumonia Severity.

Prospective isolation of NKX2-1-expressing human lung progenitors derived from pluripotent stem cells.

Interview with Darrell Kotton.

Pluripotent stem cell differentiation reveals distinct developmental pathways regulating lung- versus thyroid-lineage specification.

Differentiation of Human Pluripotent Stem Cells into Functional Lung Alveolar Epithelial Cells.

Claudin-18: unexpected regulator of lung alveolar epithelial cell proliferation.

Single-Cell Transcriptomic Profiling of Pluripotent Stem Cell-Derived SCGB3A2+ Airway Epithelium.

Derivation of Epithelial-Only Airway Organoids from Human Pluripotent Stem Cells.

Pulmonary Ionocytes Challenge the Paradigm in Cystic Fibrosis.

Generation of a Purified iPSC-Derived Smooth Muscle-like Population for Cell Sheet Engineering.

Derivation of self-renewing lung alveolar epithelial type II cells from human pluripotent stem cells.

Generation of mesenchyme free intestinal organoids from human induced pluripotent stem cells.

Reconstructed Single-Cell Fate Trajectories Define Lineage Plasticity Windows during Differentiation of Human PSC-Derived Distal Lung Progenitors.

The in vivo genetic program of murine primordial lung epithelial progenitors.

The Cellular and Physiological Basis for Lung Repair and Regeneration: Past, Present, and Future.

Hidden neural states underlie canary song syntax.

Human iPSC-derived alveolar and airway epithelial cells can be cultured at air-liquid interface and express SARS-CoV-2 host factors.

Morphological Cell Profiling of SARS-CoV-2 Infection Identifies Drug Repurposing Candidates for COVID-19.

Differentiation of human airway-organoids from induced pluripotent stem cells (iPSCs).

A Highly Phenotyped Open Access Repository of Alpha-1 Antitrypsin Deficiency Pluripotent Stem Cells.

Expression of Amyloidogenic Transthyretin Drives Hepatic Proteostasis Remodeling in an Induced Pluripotent Stem Cell Model of Systemic Amyloid Disease.

Organoids Model Transcriptional Hallmarks of Oncogenic KRAS Activation in Lung Epithelial Progenitor Cells.

SARS-CoV-2 Infection of Pluripotent Stem Cell-Derived Human Lung Alveolar Type 2 Cells Elicits a Rapid Epithelial-Intrinsic Inflammatory Response.

Common genetic variation in humans impacts susceptibility to SARS-CoV-2 infection.

Epithelial Stem and Progenitor Cells in Lung Repair and Regeneration.

Reconstructed signaling and regulatory networks identify potential drugs for SARS-CoV-2 infection.

Derivation of Airway Basal Stem Cells from Human Pluripotent Stem Cells.

Actionable Cytopathogenic Host Responses of Human Alveolar Type 2 Cells to SARS-CoV-2.

Common Genetic Variation in Humans Impacts In Vitro Susceptibility to SARS-CoV-2 Infection.

SARS-CoV-2 induces double-stranded RNA-mediated innate immune responses in respiratory epithelial-derived cells and cardiomyocytes.

SARS-CoV-2 drives JAK1/2-dependent local complement hyperactivation.

Derivation of Thyroid Follicular Cells From Pluripotent Stem Cells: Insights From Development and Implications for Regenerative Medicine.

Heterogeneity in Human Induced Pluripotent Stem Cell-derived Alveolar Epithelial Type II Cells Revealed with ABCA3/SFTPC Reporters.

Morphological cell profiling of SARS-CoV-2 infection identifies drug repurposing candidates for COVID-19.

Patient-specific iPSCs carrying an SFTPC mutation reveal the intrinsic alveolar epithelial dysfunction at the inception of interstitial lung disease.

Sequence logic at enhancers governs a dual mechanism of endodermal organ fate induction by FOXA pioneer factors.

Gaining Insight into Mitochondrial Genetic Variation and Downstream Pathophysiology: What Can i(PSCs) Do?

Human alveolar type 2 epithelium transdifferentiates into metaplastic KRT5 basal cells.

Human airway lineages derived from pluripotent stem cells reveal the epithelial responses to SARS-CoV-2 infection.

Recombinant Lloviu virus as a tool to study viral replication and host responses.

Epithelial LIF signaling limits apoptosis and lung injury during bacterial pneumonia.

CoSpar identifies early cell fate biases from single-cell transcriptomic and lineage information.

Editorial: Progenitors and Stem Cells in Thyroid Development, Disease, and Regeneration.

Specific mesoderm subset derived from human pluripotent stem cells ameliorates microvascular pathology in type 2 diabetic mice.

Air-liquid interface culture promotes maturation and allows environmental exposure of pluripotent stem cell-derived alveolar epithelium.