Department of Microbiology,
Immunology,
and Tropical Medicine,
School of Medicine and Health Sciences,
Department of Microbiology, Immunology, and Tropical Medicine, School of Medicine and Health Sciences
John M. Hawdon has not added Biography.
If you are John M. Hawdon and would like to personalize this page please email our Author Liaison for assistance.
A developmentally regulated metalloprotease secreted by host-stimulated Ancylostoma caninum third-stage infective larvae is a member of the astacin family of proteases.
Molecular and biochemical parasitology Apr, 2002 | Pubmed ID: 11897134
Molecular cloning of a novel multidomain Kunitz-type proteinase inhibitor from the hookworm Ancylostoma caninum.
The Journal of parasitology Apr, 2003 | Pubmed ID: 12760667
The second messenger cyclic GMP mediates activation in Ancylostoma caninum infective larvae.
International journal for parasitology Jul, 2003 | Pubmed ID: 12865078
Molecular characterisation of the Ancylostoma-secreted protein family from the adult stage of Ancylostoma caninum.
International journal for parasitology Aug, 2003 | Pubmed ID: 12906874
Progress in the development of a recombinant vaccine for human hookworm disease: the Human Hookworm Vaccine Initiative.
International journal for parasitology Sep, 2003 | Pubmed ID: 13678639
Phosphoinositide-3-OH-kinase inhibitor LY294002 prevents activation of Ancylostoma caninum and Ancylostoma ceylanicum third-stage infective larvae.
International journal for parasitology Jul, 2004 | Pubmed ID: 15217729
Ac-SAA-1, an immunodominant 16 kDa surface-associated antigen of infective larvae and adults of Ancylostoma caninum.
International journal for parasitology Aug, 2004 | Pubmed ID: 15313130
Cloning and characterisation of an aspartyl protease inhibitor (API-1) from Ancylostoma hookworms.
International journal for parasitology Mar, 2005 | Pubmed ID: 15722082
Identification of a DAF-7 ortholog from the hookworm Ancylostoma caninum.
International journal for parasitology Dec, 2005 | Pubmed ID: 16135366
Biochemical characterization and vaccine potential of a heme-binding glutathione transferase from the adult hookworm Ancylostoma caninum.
Infection and immunity Oct, 2005 | Pubmed ID: 16177370
Introduction of Gerhard A. Schad as the recipient of the Clark P. Read Mentor Award.
The Journal of parasitology Dec, 2005 | Pubmed ID: 16539001
Molecular cloning and DNA binding characterization of DAF-16 orthologs from Ancylostoma hookworms.
International journal for parasitology Mar, 2009 | Pubmed ID: 18930062
Interaction of hookworm 14-3-3 with the forkhead transcription factor DAF-16 requires intact Akt phosphorylation sites.
Parasites & vectors , 2009 | Pubmed ID: 19393088
Identification of the nuclear receptor DAF-12 as a therapeutic target in parasitic nematodes.
Proceedings of the National Academy of Sciences of the United States of America Jun, 2009 | Pubmed ID: 19497877
Identification of hookworm DAF-16/FOXO response elements and direct gene targets.
PloS one , 2010 | Pubmed ID: 20808816
Characterisation of hookworm heat shock factor binding protein (HSB-1) during heat shock and larval activation.
International journal for parasitology Apr, 2011 | Pubmed ID: 21172351
RNA and protein synthesis is required for Ancylostoma caninum larval activation.
Veterinary parasitology Jun, 2011 | Pubmed ID: 21354706
Controlling soil-transmitted helminths: time to think inside the box?
The Journal of parasitology Apr, 2014 | Pubmed ID: 24393037
Genome of the human hookworm Necator americanus.
Nature genetics Mar, 2014 | Pubmed ID: 24441737
Two potential hookworm DAF-16 target genes, SNR-3 and LPP-1: gene structure, expression profile, and implications of a cis-regulatory element in the regulation of gene expression.
Parasites & vectors Jan, 2015 | Pubmed ID: 25573064
Expression profile of heat shock response factors during hookworm larval activation and parasitic development.
Molecular and biochemical parasitology Jul, 2015 | Pubmed ID: 26296769
RNAi-mediated gene knockdown by microinjection in the model entomopathogenic nematode Heterorhabditis bacteriophora.
Parasites & vectors Mar, 2016 | Pubmed ID: 26993791
Acceptance of the 2016 Henry Baldwin Ward Medal - A Long and Winding Road to a Diet of Worms.
The Journal of parasitology 12, 2016 | Pubmed ID: 27529653
Microfluidic platform for electrophysiological recordings from host-stage hookworm and Ascaris suum larvae: A new tool for anthelmintic research.
International journal for parasitology. Drugs and drug resistance 12, 2016 | Pubmed ID: 27751868
Identification of candidate infection genes from the model entomopathogenic nematode Heterorhabditis bacteriophora.
BMC genomics 01, 2017 | Pubmed ID: 28049427
Refined ab initio gene predictions of Heterorhabditis bacteriophora using RNA-seq.
International journal for parasitology 07, 2018 | Pubmed ID: 29530648
Controlled Human Hookworm Infection: Accelerating Human Hookworm Vaccine Development.
Open forum infectious diseases May, 2018 | Pubmed ID: 29780848
Introduction of James "Sparky" Lok, Recipient of the 2018 Bueding and Von Brand Lectureship Award.
The Journal of parasitology 12, 2018 | Pubmed ID: 30086247
Isolation and characterization of a naturally occurring multidrug-resistant strain of the canine hookworm, Ancylostoma caninum.
International journal for parasitology 04, 2019 | Pubmed ID: 30771359
Presidential Address: Hookworm and the ASP-A Presidential Perspective.
The Journal of parasitology Dec, 2019 | Pubmed ID: 31999235
Transcriptomic analysis of hookworm Ancylostoma ceylanicum life cycle stages reveals changes in G-protein coupled receptor diversity associated with the onset of parasitism.
International journal for parasitology 07, 2020 | Pubmed ID: 32592811
A putative UDP-glycosyltransferase from Heterorhabditis bacteriophora suppresses antimicrobial peptide gene expression and factors related to ecdysone signaling.
Scientific reports 07, 2020 | Pubmed ID: 32704134
A putative lysozyme and serine carboxypeptidase from Heterorhabditis bacteriophora show differential virulence capacities in Drosophila melanogaster.
Developmental and comparative immunology 01, 2021 | Pubmed ID: 32791175
NemChR-DB: a database of parasitic nematode chemosensory G-protein coupled receptors.
International journal for parasitology 04, 2021 | Pubmed ID: 33275943
Secreted virulence factors from Heterorhabditis bacteriophora highlight its utility as a model parasite among Clade V nematodes.
International journal for parasitology 04, 2021 | Pubmed ID: 33421438
Chemogenomic approach to identifying nematode chemoreceptor drug targets in the entomopathogenic nematode Heterorhabditis bacteriophora.
Computational biology and chemistry Jun, 2021 | Pubmed ID: 33667976
Controlled Infection of Humans with the Hookworm Parasite Necator americanus to Accelerate Vaccine Development : The Human Hookworm Vaccination/Challenge Model (HVCM).
Current topics in microbiology and immunology Jul, 2021 | Pubmed ID: 34328562
ACERCA DE JoVE
Copyright © 2024 MyJoVE Corporation. Todos los derechos reservados