Department of Microbiology,
Immunology,
and Tropical Medicine,
School of Medicine and Health Sciences,
Department of Microbiology, Immunology, and Tropical Medicine, School of Medicine and Health Sciences
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A developmentally regulated metalloprotease secreted by host-stimulated Ancylostoma caninum third-stage infective larvae is a member of the astacin family of proteases.
Molecular and biochemical parasitology Apr, 2002 | Pubmed ID: 11897134
Molecular cloning of a novel multidomain Kunitz-type proteinase inhibitor from the hookworm Ancylostoma caninum.
The Journal of parasitology Apr, 2003 | Pubmed ID: 12760667
The second messenger cyclic GMP mediates activation in Ancylostoma caninum infective larvae.
International journal for parasitology Jul, 2003 | Pubmed ID: 12865078
Molecular characterisation of the Ancylostoma-secreted protein family from the adult stage of Ancylostoma caninum.
International journal for parasitology Aug, 2003 | Pubmed ID: 12906874
Progress in the development of a recombinant vaccine for human hookworm disease: the Human Hookworm Vaccine Initiative.
International journal for parasitology Sep, 2003 | Pubmed ID: 13678639
Phosphoinositide-3-OH-kinase inhibitor LY294002 prevents activation of Ancylostoma caninum and Ancylostoma ceylanicum third-stage infective larvae.
International journal for parasitology Jul, 2004 | Pubmed ID: 15217729
Ac-SAA-1, an immunodominant 16 kDa surface-associated antigen of infective larvae and adults of Ancylostoma caninum.
International journal for parasitology Aug, 2004 | Pubmed ID: 15313130
Cloning and characterisation of an aspartyl protease inhibitor (API-1) from Ancylostoma hookworms.
International journal for parasitology Mar, 2005 | Pubmed ID: 15722082
Identification of a DAF-7 ortholog from the hookworm Ancylostoma caninum.
International journal for parasitology Dec, 2005 | Pubmed ID: 16135366
Biochemical characterization and vaccine potential of a heme-binding glutathione transferase from the adult hookworm Ancylostoma caninum.
Infection and immunity Oct, 2005 | Pubmed ID: 16177370
Introduction of Gerhard A. Schad as the recipient of the Clark P. Read Mentor Award.
The Journal of parasitology Dec, 2005 | Pubmed ID: 16539001
Molecular cloning and DNA binding characterization of DAF-16 orthologs from Ancylostoma hookworms.
International journal for parasitology Mar, 2009 | Pubmed ID: 18930062
Interaction of hookworm 14-3-3 with the forkhead transcription factor DAF-16 requires intact Akt phosphorylation sites.
Parasites & vectors , 2009 | Pubmed ID: 19393088
Identification of the nuclear receptor DAF-12 as a therapeutic target in parasitic nematodes.
Proceedings of the National Academy of Sciences of the United States of America Jun, 2009 | Pubmed ID: 19497877
Identification of hookworm DAF-16/FOXO response elements and direct gene targets.
PloS one , 2010 | Pubmed ID: 20808816
Characterisation of hookworm heat shock factor binding protein (HSB-1) during heat shock and larval activation.
International journal for parasitology Apr, 2011 | Pubmed ID: 21172351
RNA and protein synthesis is required for Ancylostoma caninum larval activation.
Veterinary parasitology Jun, 2011 | Pubmed ID: 21354706
Controlling soil-transmitted helminths: time to think inside the box?
The Journal of parasitology Apr, 2014 | Pubmed ID: 24393037
Genome of the human hookworm Necator americanus.
Nature genetics Mar, 2014 | Pubmed ID: 24441737
Two potential hookworm DAF-16 target genes, SNR-3 and LPP-1: gene structure, expression profile, and implications of a cis-regulatory element in the regulation of gene expression.
Parasites & vectors Jan, 2015 | Pubmed ID: 25573064
Expression profile of heat shock response factors during hookworm larval activation and parasitic development.
Molecular and biochemical parasitology Jul, 2015 | Pubmed ID: 26296769
RNAi-mediated gene knockdown by microinjection in the model entomopathogenic nematode Heterorhabditis bacteriophora.
Parasites & vectors Mar, 2016 | Pubmed ID: 26993791
Acceptance of the 2016 Henry Baldwin Ward Medal - A Long and Winding Road to a Diet of Worms.
The Journal of parasitology 12, 2016 | Pubmed ID: 27529653
Microfluidic platform for electrophysiological recordings from host-stage hookworm and Ascaris suum larvae: A new tool for anthelmintic research.
International journal for parasitology. Drugs and drug resistance 12, 2016 | Pubmed ID: 27751868
Identification of candidate infection genes from the model entomopathogenic nematode Heterorhabditis bacteriophora.
BMC genomics 01, 2017 | Pubmed ID: 28049427
Refined ab initio gene predictions of Heterorhabditis bacteriophora using RNA-seq.
International journal for parasitology 07, 2018 | Pubmed ID: 29530648
Controlled Human Hookworm Infection: Accelerating Human Hookworm Vaccine Development.
Open forum infectious diseases May, 2018 | Pubmed ID: 29780848
Introduction of James "Sparky" Lok, Recipient of the 2018 Bueding and Von Brand Lectureship Award.
The Journal of parasitology 12, 2018 | Pubmed ID: 30086247
Isolation and characterization of a naturally occurring multidrug-resistant strain of the canine hookworm, Ancylostoma caninum.
International journal for parasitology 04, 2019 | Pubmed ID: 30771359
Presidential Address: Hookworm and the ASP-A Presidential Perspective.
The Journal of parasitology Dec, 2019 | Pubmed ID: 31999235
Transcriptomic analysis of hookworm Ancylostoma ceylanicum life cycle stages reveals changes in G-protein coupled receptor diversity associated with the onset of parasitism.
International journal for parasitology 07, 2020 | Pubmed ID: 32592811
A putative UDP-glycosyltransferase from Heterorhabditis bacteriophora suppresses antimicrobial peptide gene expression and factors related to ecdysone signaling.
Scientific reports 07, 2020 | Pubmed ID: 32704134
A putative lysozyme and serine carboxypeptidase from Heterorhabditis bacteriophora show differential virulence capacities in Drosophila melanogaster.
Developmental and comparative immunology 01, 2021 | Pubmed ID: 32791175
NemChR-DB: a database of parasitic nematode chemosensory G-protein coupled receptors.
International journal for parasitology 04, 2021 | Pubmed ID: 33275943
Secreted virulence factors from Heterorhabditis bacteriophora highlight its utility as a model parasite among Clade V nematodes.
International journal for parasitology 04, 2021 | Pubmed ID: 33421438
Chemogenomic approach to identifying nematode chemoreceptor drug targets in the entomopathogenic nematode Heterorhabditis bacteriophora.
Computational biology and chemistry Jun, 2021 | Pubmed ID: 33667976
Controlled Infection of Humans with the Hookworm Parasite Necator americanus to Accelerate Vaccine Development : The Human Hookworm Vaccination/Challenge Model (HVCM).
Current topics in microbiology and immunology Jul, 2021 | Pubmed ID: 34328562