Obstetrics and Gynecology Hospital,
Institute of Reproduction and Development,
Obstetrics and Gynecology Hospital, Institute of Reproduction and Development
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Methylation levels at IGF2 and GNAS DMRs in infants born to preeclamptic pregnancies.
BMC genomics Jul, 2013 | Pubmed ID: 23844573
Reduced fetal telomere length in gestational diabetes.
PloS one , 2014 | Pubmed ID: 24465936
Alteration in methylation level at 11β-hydroxysteroid dehydrogenase type 2 gene promoter in infants born to preeclamptic women.
BMC genetics Sep, 2014 | Pubmed ID: 25200528
Increased methylation at differentially methylated region of GNAS in infants born to gestational diabetes.
BMC medical genetics Oct, 2014 | Pubmed ID: 25269528
Enhancing the precision of genetic lineage tracing using dual recombinases.
Nature medicine Dec, 2017 | Pubmed ID: 29131159
Basonuclin 1 deficiency is a cause of primary ovarian insufficiency.
Human molecular genetics Nov, 2018 | Pubmed ID: 30010909
Early-life undernutrition reprograms CD4 T-cell glycolysis and epigenetics to facilitate asthma.
The Journal of allergy and clinical immunology Jun, 2019 | Pubmed ID: 30654047
Dietary restriction and/or exercise training impairs spermatogenesis in normal rats.
Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme Mar, 2021 | Pubmed ID: 32905708
Maternal high-fat-diet exposure is associated with elevated blood pressure and sustained increased leptin levels through epigenetic memory in offspring.
Scientific reports 01, 2021 | Pubmed ID: 33431976
Elevated ovarian pentraxin 3 in polycystic ovary syndrome.
Journal of assisted reproduction and genetics May, 2021 | Pubmed ID: 33594624
Abnormal Glucose Metabolism in Male Mice Offspring Conceived by Fertilization and Frozen-Thawed Embryo Transfer.
Frontiers in cell and developmental biology , 2021 | Pubmed ID: 33634140
Effects of acute ambient pollution exposure on preterm prelabor rupture of membranes: A time-series analysis in Shanghai, China.
Environmental pollution (Barking, Essex : 1987) May, 2021 | Pubmed ID: 33662814
Alternations of cesarean section rates in a non-infected population after the outbreak of COVID-19: a cross-sectional study.
Psychology, health & medicine Oct, 2022 | Pubmed ID: 33715523
Study protocol for the Sino-Canadian Healthy Life Trajectories Initiative (SCHeLTI): a multicentre, cluster-randomised, parallel-group, superiority trial of a multifaceted community-family-mother-child intervention to prevent childhood overweight and obesity.
BMJ open Apr, 2021 | Pubmed ID: 33795307
Paternal obesity impairs hepatic gluconeogenesis of offspring by altering Igf2/H19 DNA methylation.
Molecular and cellular endocrinology Jun, 2021 | Pubmed ID: 33811969
Caregivers' perceptions, challenges and service needs related to tackling childhood overweight and obesity: a qualitative study in three districts of Shanghai, China.
BMC public health Apr, 2021 | Pubmed ID: 33882878
Perinatal outcomes of neonates born from different endometrial preparation protocols after frozen embryo transfer: a retrospective cohort study.
BMC pregnancy and childbirth Apr, 2021 | Pubmed ID: 33926401
Effect of embryo cryopreservation duration on pregnancy-related complications and birthweight after frozen-thawed embryo transfer: a retrospective cohort study.
Journal of developmental origins of health and disease Apr, 2022 | Pubmed ID: 33947503
Gestational high-fat diet impaired demethylation of Pparα and induced obesity of offspring.
Journal of cellular and molecular medicine Jun, 2021 | Pubmed ID: 33955677
Association of homocysteine with IVF/ICSI outcomes stratified by MTHFR C677T polymorphisms: a prospective cohort study.
Reproductive biomedicine online Jul, 2021 | Pubmed ID: 34016520
Expanding the Scope of Non-invasive Prenatal Testing to Detect Fetal Chromosomal Copy Number Variations.
Frontiers in molecular biosciences , 2021 | Pubmed ID: 34055879
Neurogenesis Potential Evaluation and Transcriptome Analysis of Fetal Hypothalamic Neural Stem/Progenitor Cells With Prenatal High Estradiol Exposure.
Frontiers in genetics , 2021 | Pubmed ID: 34239542
Low-level germline mosaicism of a novel SMARCA2 missense variant: Expanding the phenotypic spectrum and mode of genetic transmission.
Molecular genetics & genomic medicine Sep, 2021 | Pubmed ID: 34296532
Comparison of Genome-Wide DNA Methylation Profiles of Human Fetal Tissues Conceived by Fertilization and Natural Conception.
Frontiers in cell and developmental biology , 2021 | Pubmed ID: 34336842
Association Between Paternal Age and Birth Weight in Preterm and Full-Term Birth: A Retrospective Study.
Frontiers in endocrinology , 2021 | Pubmed ID: 34367073
Adverse Maternal and Neonatal Outcomes in Women With Elevated Intrapartum Temperature Complicated by Histological Chorioamnionitis at Term: A Propensity-Score Matched Study.
Frontiers in pediatrics , 2021 | Pubmed ID: 34368025
Anti-Müllerian Hormone Accelerates Pathological Process of Insulin Resistance in Polycystic Ovary Syndrome Patients.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme Aug, 2021 | Pubmed ID: 34384107
Intrauterine hyperglycemia impairs memory across two generations.
Translational psychiatry Aug, 2021 | Pubmed ID: 34417446
Effect of an individualised nutritional intervention on gestational diabetes mellitus prevention in a high-risk population screened by a prediction model: study protocol for a multicentre randomised controlled trial.
BMC pregnancy and childbirth Aug, 2021 | Pubmed ID: 34429102
Comprehensive non-invasive prenatal screening for pregnancies with elevated risks of genetic disorders: protocol for a prospective, multicentre study.
BMJ open Aug, 2021 | Pubmed ID: 34452972
Different Strategies of Preimplantation Genetic Testing for Aneuploidies in Women of Advanced Maternal Age: A Systematic Review and Meta-Analysis.
Journal of clinical medicine Aug, 2021 | Pubmed ID: 34501345
Intrauterine Hyperglycemia Alters the Metabolomic Profile in Fetal Mouse Pancreas in a Gender-Specific Manner.
Frontiers in endocrinology , 2021 | Pubmed ID: 34531826
Anxiety and depression-like behaviours are more frequent in aged male mice conceived by ART compared with natural conception.
Reproduction (Cambridge, England) Oct, 2021 | Pubmed ID: 34605773
COVID-19 Lockdown Increased the Risk of Preterm Birth.
Frontiers in medicine , 2021 | Pubmed ID: 34646839
The Impact of Gestational Weight Gain on the Risks of Adverse Maternal and Infant Outcomes among Normal BMI Women with High Triglyceride Levels during Early Pregnancy.
Nutrients Sep, 2021 | Pubmed ID: 34684457
Optogenetic Activation of Arcuate Kisspeptin Neurons Generates a Luteinizing Hormone Surge-Like Secretion in an Estradiol-Dependent Manner.
Frontiers in endocrinology , 2021 | Pubmed ID: 34795643
Classification and Interpretation for 11 FBN1 Variants Responsible for Marfan Syndrome and Pre-implantation Genetic Testing (PGT) for Two Families Successfully Blocked Transmission of the Pathogenic Mutations.
Frontiers in molecular biosciences , 2021 | Pubmed ID: 34957211
Circulating Innate Lymphoid Cells Exhibit Distinctive Distribution During Normal Pregnancy.
Reproductive sciences (Thousand Oaks, Calif.) Apr, 2022 | Pubmed ID: 34988918
Association between prenatal exposure to ambient air pollutants and postpartum depressive symptoms: A multi-city cohort study.
Environmental research Jun, 2022 | Pubmed ID: 35077713
Advanced paternal age increased metabolic risks in mice offspring.
Biochimica et biophysica acta. Molecular basis of disease May, 2022 | Pubmed ID: 35131436
Associations of PM exposure with blood glucose impairment in early pregnancy and gestational diabetes mellitus.
Ecotoxicology and environmental safety Mar, 2022 | Pubmed ID: 35131583
HSD17B12 dosage insufficiency induced premature ovarian insufficiency in humans and mice.
Clinical and translational medicine Feb, 2022 | Pubmed ID: 35187845
Integrated Multi-Omics Analysis Reveals the Effect of Maternal Gestational Diabetes on Fetal Mouse Hippocampi.
Frontiers in cell and developmental biology , 2022 | Pubmed ID: 35237591
Environmental epigenetic interaction of gametes and early embryos†.
Biology of reproduction Jul, 2022 | Pubmed ID: 35323884
Effects of Paternal Obesity on Fetal Development and Pregnancy Complications: A Prospective Clinical Cohort Study.
Frontiers in endocrinology , 2022 | Pubmed ID: 35360083
Association between paternal age and subtypes of preterm birth: a retrospective study.
Reproductive biomedicine online Jun, 2022 | Pubmed ID: 35400578
Maternal inheritance of glucose intolerance via oocyte TET3 insufficiency.
Nature May, 2022 | Pubmed ID: 35585240
Exposure to Chloramine and Chloroform in Tap Water and Adverse Perinatal Outcomes in Shanghai.
International journal of environmental research and public health May, 2022 | Pubmed ID: 35682093
Maternal High-Fat Diet Aggravates Allergic Asthma in Offspring via Modulating CD4 T-Cell Differentiation.
Nutrients Jun, 2022 | Pubmed ID: 35745240
Diabetes predisposition inherited through maternal germline.
Clinical and translational medicine Jul, 2022 | Pubmed ID: 35802824
Preimplantation genetic testing for aneuploidy in severe male factor infertility: protocol for a multicenter randomised controlled trial.
BMJ open Jul, 2022 | Pubmed ID: 35831058
Associations Between Asthma and Polycystic Ovary Syndrome: Current Perspectives.
Frontiers in endocrinology , 2022 | Pubmed ID: 35865312
Lysophosphatidic Acid Improves Human Sperm Motility by Enhancing Glycolysis and Activating L-Type Calcium Channels.
Frontiers in endocrinology , 2022 | Pubmed ID: 35903269
Tracking of menstrual cycles and prediction of the fertile window via measurements of basal body temperature and heart rate as well as machine-learning algorithms.
Reproductive biology and endocrinology : RB&E Aug, 2022 | Pubmed ID: 35964035
Effect of Maternal Glucose and Triglyceride Levels during Early Pregnancy on Pregnancy Outcomes: A Retrospective Cohort Study.
Nutrients Aug, 2022 | Pubmed ID: 36014801
Interactive effects of ambient air pollution and sunshine duration on the risk of intrahepatic cholestasis of pregnancy.
Environmental research Dec, 2022 | Pubmed ID: 36116502
Internet-based cognitive therapy for women with antenatal depressive symptoms during the COVID-19 pandemic: protocol for a multi-center randomized controlled trial across China.
Trials Sep, 2022 | Pubmed ID: 36131289
Living birth following preimplantation genetic testing for monogenic disorders to prevent low-level germline mosaicism related Nicolaides-Baraitser syndrome.
Frontiers in genetics , 2022 | Pubmed ID: 36160002
LncRNA THOR promotes endometrial cancer progression through the AKT and ERK signaling pathways.
Medical oncology (Northwood, London, England) Sep, 2022 | Pubmed ID: 36175594
Maternal lipid profile during early pregnancy and birth weight: A retrospective study.
Frontiers in endocrinology , 2022 | Pubmed ID: 36187100
Genetic deconvolution of fetal and maternal cell-free DNA in maternal plasma enables next-generation non-invasive prenatal screening.
Cell discovery Oct, 2022 | Pubmed ID: 36229437
Editorial: Polycystic ovary syndrome (PCOS): Mechanism and management.
Frontiers in endocrinology , 2022 | Pubmed ID: 36277701
Breastfeeding Practices and Associated Factors in Shanghai: A Cross-Sectional Study.
Nutrients Oct, 2022 | Pubmed ID: 36297120
The lncRNA THOR interacts with and stabilizes hnRNPD to promote cell proliferation and metastasis in breast cancer.
Oncogene Dec, 2022 | Pubmed ID: 36329124
Construction of a ceRNA network in polycystic ovary syndrome (PCOS) driven by exosomal lncRNA.
Frontiers in genetics , 2022 | Pubmed ID: 36406137
Associations between short-term and long-term exposure to particulate matter and preterm birth.
Chemosphere Feb, 2023 | Pubmed ID: 36455656
Association of maternal triglyceride responses to thyroid function in early pregnancy with gestational diabetes mellitus.
Frontiers in endocrinology , 2022 | Pubmed ID: 36518243
Small RNA perspective of physical exercise-related improvement of male reproductive dysfunction due to obesity.
Frontiers in endocrinology , 2022 | Pubmed ID: 36531465
The epigenetic mechanisms underlying gamete origin of adult-onset diseases.
Science bulletin Sep, 2022 | Pubmed ID: 36546054
Effects of parental overweight and obesity on offspring's mental health: A meta-analysis of observational studies.
PloS one , 2022 | Pubmed ID: 36548252
A PPARG Splice Variant in Granulosa Cells Is Associated with Polycystic Ovary Syndrome.
Journal of clinical medicine Dec, 2022 | Pubmed ID: 36555903
Association between Plasma Trace Element Concentrations in Early Pregnancy and Gestational Diabetes Mellitus in Shanghai, China.
Nutrients Dec, 2022 | Pubmed ID: 36615774
Parental mosaicism detection and preimplantation genetic testing in families with multiple transmissions of de novo mutations.
Journal of medical genetics Sep, 2023 | Pubmed ID: 36707240
Characteristics and possible mechanisms of metabolic disorder in overweight women with polycystic ovary syndrome.
Frontiers in endocrinology , 2022 | Pubmed ID: 36714563
Delivery and neonatal outcomes of pregnant women during the Shanghai lockdown: A retrospective analysis.
Frontiers in pediatrics , 2023 | Pubmed ID: 36816385
Preimplantation Genetic Testing (PGT) and Prenatal Diagnosis of Schaaf-Yang Syndrome: A Report of Three Families and a Research on Genotype-Phenotype Correlations.
Journal of clinical medicine Feb, 2023 | Pubmed ID: 36836222
Comparative effectiveness of transvaginal repair vs. hysteroscopic resection in patients with symptomatic uterine niche.
Frontiers in surgery , 2023 | Pubmed ID: 36843994
An intergenerational life-course approach to address early childhood obesity and adiposity: the Healthy Life Trajectories Initiative (HeLTI).
The Lancet. Global health Mar, 2023 | Pubmed ID: 36866472
Serum anti-Müllerian hormone levels are associated with perinatal outcomes in women undergoing IVF/ICSI: A multicenter retrospective cohort study.
Frontiers in endocrinology , 2023 | Pubmed ID: 36896183
Effects of Particulate Matter on the Risk of Gestational Hypertensive Disorders and Their Progression.
Environmental science & technology Mar, 2023 | Pubmed ID: 36913485
Effect of Frozen-Thawed Embryo Transfer on the Metabolism of Children in Early Childhood.
Journal of clinical medicine Mar, 2023 | Pubmed ID: 36983323
Mixed exposure effect of seminal metals on semen quality, mediation of total antioxidant capacity, and moderation of GSTM1/GSTT1 gene deletion in Chinese reproductive-aged men.
Environmental research Jul, 2023 | Pubmed ID: 37054833
The causal association between smoking initiation, alcohol and coffee consumption, and women's reproductive health: A two-sample Mendelian randomization analysis.
Frontiers in genetics , 2023 | Pubmed ID: 37091804
Sperm morphological abnormalities in autosomal dominant polycystic kidney disease are associated with the Hippo signaling pathway via PC1.
Frontiers in endocrinology , 2023 | Pubmed ID: 37152951
Developmental origins of diabetes mellitus: Environmental epigenomics and emerging patterns.
Journal of diabetes Jul, 2023 | Pubmed ID: 37190864
Biallelic variants in RBM42 cause a multisystem disorder with neurological, facial, cardiac, and musculoskeletal involvement.
Protein & cell Jan, 2024 | Pubmed ID: 37294900
The Influences of Perinatal Androgenic Exposure on Cardiovascular and Metabolic Disease of Offspring of PCOS.
Reproductive sciences (Thousand Oaks, Calif.) Nov, 2023 | Pubmed ID: 37380913
Machine learning and bioinformatics framework integration reveal potential characteristic genes related to immune cell infiltration in preeclampsia.
Frontiers in physiology , 2023 | Pubmed ID: 37389124
Elevated follicular cortisone level is a negative predictor of clinical pregnancy in women undergoing fresh embryo transfer.
Heliyon Jul, 2023 | Pubmed ID: 37415947
Carrier burden of over 300 diseases in Han Chinese identified by expanded carrier testing of 300 couples using assisted reproductive technology.
Journal of assisted reproduction and genetics Sep, 2023 | Pubmed ID: 37450097
Fetal weight estimation based on deep neural network: a retrospective observational study.
BMC pregnancy and childbirth Aug, 2023 | Pubmed ID: 37533038
Research Progress of Maternal Metabolism on Cardiac Development and Function in Offspring.
Nutrients Jul, 2023 | Pubmed ID: 37571325
Rare loss-of-function variants reveal threshold and multifactorial inheritance of dextrocardia.
Science bulletin Sep, 2023 | Pubmed ID: 37573248
Editorial: Polycystic ovary syndrome: mechanism and management-volume II.
Frontiers in endocrinology , 2023 | Pubmed ID: 37588987
Noninvasive Evaluation of Fetal Zygosity in Twin Pregnancies Involving a Binary Analysis of Single-Nucleotide Polymorphisms.
The Journal of molecular diagnostics : JMD Sep, 2023 | Pubmed ID: 37599029
Overexpression of Pde4d in rat granulosa cells inhibits maturation and atresia of antral follicles to induce polycystic ovary.
Biochimica et biophysica acta. Molecular basis of disease Jan, 2024 | Pubmed ID: 37673361
Developmental origins of adult diseases.
Medical review (Berlin, Germany) Oct, 2022 | Pubmed ID: 37724166
Recurrent human 16p11.2 microdeletions in type I Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome patients in Chinese Han population.
Molecular genetics & genomic medicine Jan, 2024 | Pubmed ID: 37789575
NLRP3 Inflammasome-dependent Pathway is Involved in the Pathogenesis of Polycystic Ovary Syndrome.
Reproductive sciences (Thousand Oaks, Calif.) Apr, 2024 | Pubmed ID: 37815748
Early characterisation and prediction of liver diseases in pregnancy by plasma cell-free RNAs.
Clinical and translational medicine Oct, 2023 | Pubmed ID: 37830149
Follicle-stimulating hormone orchestrates glucose-stimulated insulin secretion of pancreatic islets.
Nature communications Nov, 2023 | Pubmed ID: 37914684
Assisted reproductive technology and imprinting errors: analyzing underlying mechanisms from epigenetic regulation.
Human fertility (Cambridge, England) Nov, 2023 | Pubmed ID: 37929309
Polycystic Ovary Syndrome Fuels Cardiovascular Inflammation and Aggravates Ischemic Cardiac Injury.
Circulation Dec, 2023 | Pubmed ID: 37937441
Chinese experts' consensus guideline on preimplantation genetic testing of monogenic disorders.
Human reproduction (Oxford, England) Nov, 2023 | Pubmed ID: 37982416
Research Progress on the effects of adverse exposure during pregnancy on skeletal muscle function in offspring.
Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences Nov, 2023 | Pubmed ID: 37986679
Research progress and challenges of preimplantation genetic testing for polygenic diseases.
Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences Nov, 2023 | Pubmed ID: 37987034
Prediction of shared gene signatures and biological mechanisms between polycystic ovary syndrome and asthma: Based on weighted gene coexpression network analysis.
International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics Apr, 2024 | Pubmed ID: 38055328
Metabolome implies increased fatty acid utilization and histone methylation in the follicles from hyperandrogenic PCOS women.
The Journal of nutritional biochemistry Mar, 2024 | Pubmed ID: 38104867
Sexual behavior and cardiovascular diseases: univariable and multivariable Mendelian randomization.
Frontiers in cardiovascular medicine , 2023 | Pubmed ID: 38116537
Effect of transvaginal Lactobacillus supplementation on reversing lower genital tract dysbiosis and improving perinatal outcomes in PCOS patients after IVF-FET: a study protocol for a multicenter randomized controlled trial.
Trials Dec, 2023 | Pubmed ID: 38129882
Long-term health risk of offspring born from assisted reproductive technologies.
Journal of assisted reproduction and genetics Mar, 2024 | Pubmed ID: 38146031
Prospective prenatal cell-free DNA screening for genetic conditions of heterogenous etiologies.
Nature medicine Feb, 2024 | Pubmed ID: 38253798
Cardiovascular health of offspring conceived by assisted reproduction technology: a comprehensive review.
Frontiers in cardiovascular medicine , 2024 | Pubmed ID: 38292241
LncRNA SNHG5 adversely governs follicular growth in PCOS via miR-92a-3p/CDKN1C axis.
iScience Feb, 2024 | Pubmed ID: 38313057
Practice guideline on ovarian tissue cryopreservation and transplantation in the prevention and treatment of iatrogenic premature ovarian insufficiency.
Maturitas Apr, 2024 | Pubmed ID: 38325136
A mutual comparison of pregnancy outcomes between different conception modes: a propensity score matching based retrospective cohort study.
Frontiers in endocrinology , 2024 | Pubmed ID: 38332889
A morphological study of symptomatic uterine niche using three-dimensional models from thin-slice magnetic resonance imaging.
Reproductive biomedicine online Apr, 2024 | Pubmed ID: 38340538
Association of serum folic acid levels in response to fasting blood glucose in early pregnancy with the risk of gestational diabetes mellitus: A retrospective cohort study.
Nutrition (Burbank, Los Angeles County, Calif.) Jun, 2024 | Pubmed ID: 38422754
A novel preimplantation genetic testing strategy for a subtelomeric genetic disorder: A case study.
Genes & diseases Jul, 2024 | Pubmed ID: 38425427
Sex-Specific Alterations in Placental Proteomics Induced by Intrauterine Hyperglycemia.
Journal of proteome research Apr, 2024 | Pubmed ID: 38470452
Reduction in Placental Metal and Metalloid in Preeclampsia: A Case-Control Study.
Nutrients Mar, 2024 | Pubmed ID: 38542681
The impact of maternal age on aneuploidy in oocytes: Reproductive consequences, molecular mechanisms, and future directions.
Ageing research reviews Jun, 2024 | Pubmed ID: 38582380
FSH regulates glucose-stimulated insulin secretion: A bell-shaped curve effect.
Journal of diabetes Apr, 2024 | Pubmed ID: 38599851
Pre-eclamptic foetal programming predisposes offspring to hepatic steatosis via DNA methylation.
Biochimica et biophysica acta. Molecular basis of disease Jun, 2024 | Pubmed ID: 38648899
Characterization of a novel adipose tissue located between abdominal lymph nodes and cervix/prostate in mice.
American journal of physiology. Endocrinology and metabolism May, 2024 | Pubmed ID: 38747899
Intrauterine hyperglycemia induces SIRT3-mediated mitochondrial dysfunction: the fetal origin pathogenesis of precocious osteoarthritis.
Osteoarthritis and cartilage May, 2024 | Pubmed ID: 38782252
Cerium Oxide Nanozymes Improve Skeletal Muscle Function in Gestational Diabetic Offspring by Attenuating Mitochondrial Oxidative Stress.
ACS omega May, 2024 | Pubmed ID: 38799328
Deamidation enables pathogenic SMAD6 variants to activate the BMP signaling pathway.
Science China. Life sciences Jun, 2024 | Pubmed ID: 38913236
Effects of exposure to multiple metallic elements in the first trimester of pregnancy on the risk of preterm birth.
Maternal & child nutrition Jun, 2024 | Pubmed ID: 38925571
[Reproductive Health-Oriented Development in Assisted Reproductive Technologies].
Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition May, 2024 | Pubmed ID: 38948299
1Obstetrics and Gynecology Hospital, Institute of Reproduction and Development, Fudan University,
2Women's Hospital, Key Laboratory of Reproductive Genetics (Ministry of Education), Zhejiang University School of Medicine,
3International Institutes of Medicine, the Fourth Affiliated Hospital, Zhejiang University School of Medicine,
4Research Units of Embryo Original Diseases, Chinese Academy of Medical Sciences (No. 2019RU056),
5, State Key Laboratory of Cardiology
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