Hefeng Huang

Methylation levels at IGF2 and GNAS DMRs in infants born to preeclamptic pregnancies.

Reduced fetal telomere length in gestational diabetes.

Alteration in methylation level at 11β-hydroxysteroid dehydrogenase type 2 gene promoter in infants born to preeclamptic women.

Increased methylation at differentially methylated region of GNAS in infants born to gestational diabetes.

Enhancing the precision of genetic lineage tracing using dual recombinases.

Basonuclin 1 deficiency is a cause of primary ovarian insufficiency.

Early-life undernutrition reprograms CD4 T-cell glycolysis and epigenetics to facilitate asthma.

Dietary restriction and/or exercise training impairs spermatogenesis in normal rats.

Maternal high-fat-diet exposure is associated with elevated blood pressure and sustained increased leptin levels through epigenetic memory in offspring.

Elevated ovarian pentraxin 3 in polycystic ovary syndrome.

Abnormal Glucose Metabolism in Male Mice Offspring Conceived by Fertilization and Frozen-Thawed Embryo Transfer.

Effects of acute ambient pollution exposure on preterm prelabor rupture of membranes: A time-series analysis in Shanghai, China.

Alternations of cesarean section rates in a non-infected population after the outbreak of COVID-19: a cross-sectional study.

Study protocol for the Sino-Canadian Healthy Life Trajectories Initiative (SCHeLTI): a multicentre, cluster-randomised, parallel-group, superiority trial of a multifaceted community-family-mother-child intervention to prevent childhood overweight and obesity.

Paternal obesity impairs hepatic gluconeogenesis of offspring by altering Igf2/H19 DNA methylation.

Caregivers' perceptions, challenges and service needs related to tackling childhood overweight and obesity: a qualitative study in three districts of Shanghai, China.

Perinatal outcomes of neonates born from different endometrial preparation protocols after frozen embryo transfer: a retrospective cohort study.

Effect of embryo cryopreservation duration on pregnancy-related complications and birthweight after frozen-thawed embryo transfer: a retrospective cohort study.

Gestational high-fat diet impaired demethylation of Pparα and induced obesity of offspring.

Association of homocysteine with IVF/ICSI outcomes stratified by MTHFR C677T polymorphisms: a prospective cohort study.

Expanding the Scope of Non-invasive Prenatal Testing to Detect Fetal Chromosomal Copy Number Variations.

Neurogenesis Potential Evaluation and Transcriptome Analysis of Fetal Hypothalamic Neural Stem/Progenitor Cells With Prenatal High Estradiol Exposure.

Low-level germline mosaicism of a novel SMARCA2 missense variant: Expanding the phenotypic spectrum and mode of genetic transmission.

Comparison of Genome-Wide DNA Methylation Profiles of Human Fetal Tissues Conceived by Fertilization and Natural Conception.

Association Between Paternal Age and Birth Weight in Preterm and Full-Term Birth: A Retrospective Study.

Adverse Maternal and Neonatal Outcomes in Women With Elevated Intrapartum Temperature Complicated by Histological Chorioamnionitis at Term: A Propensity-Score Matched Study.

Anti-Müllerian Hormone Accelerates Pathological Process of Insulin Resistance in Polycystic Ovary Syndrome Patients.

Intrauterine hyperglycemia impairs memory across two generations.

Effect of an individualised nutritional intervention on gestational diabetes mellitus prevention in a high-risk population screened by a prediction model: study protocol for a multicentre randomised controlled trial.

Comprehensive non-invasive prenatal screening for pregnancies with elevated risks of genetic disorders: protocol for a prospective, multicentre study.

Different Strategies of Preimplantation Genetic Testing for Aneuploidies in Women of Advanced Maternal Age: A Systematic Review and Meta-Analysis.

Intrauterine Hyperglycemia Alters the Metabolomic Profile in Fetal Mouse Pancreas in a Gender-Specific Manner.

Anxiety and depression-like behaviours are more frequent in aged male mice conceived by ART compared with natural conception.

COVID-19 Lockdown Increased the Risk of Preterm Birth.

The Impact of Gestational Weight Gain on the Risks of Adverse Maternal and Infant Outcomes among Normal BMI Women with High Triglyceride Levels during Early Pregnancy.

Optogenetic Activation of Arcuate Kisspeptin Neurons Generates a Luteinizing Hormone Surge-Like Secretion in an Estradiol-Dependent Manner.

Classification and Interpretation for 11 FBN1 Variants Responsible for Marfan Syndrome and Pre-implantation Genetic Testing (PGT) for Two Families Successfully Blocked Transmission of the Pathogenic Mutations.

Circulating Innate Lymphoid Cells Exhibit Distinctive Distribution During Normal Pregnancy.

Association between prenatal exposure to ambient air pollutants and postpartum depressive symptoms: A multi-city cohort study.

Advanced paternal age increased metabolic risks in mice offspring.

Associations of PM exposure with blood glucose impairment in early pregnancy and gestational diabetes mellitus.

HSD17B12 dosage insufficiency induced premature ovarian insufficiency in humans and mice.

Integrated Multi-Omics Analysis Reveals the Effect of Maternal Gestational Diabetes on Fetal Mouse Hippocampi.

Environmental epigenetic interaction of gametes and early embryos†.

Effects of Paternal Obesity on Fetal Development and Pregnancy Complications: A Prospective Clinical Cohort Study.

Association between paternal age and subtypes of preterm birth: a retrospective study.

Maternal inheritance of glucose intolerance via oocyte TET3 insufficiency.

Exposure to Chloramine and Chloroform in Tap Water and Adverse Perinatal Outcomes in Shanghai.

Maternal High-Fat Diet Aggravates Allergic Asthma in Offspring via Modulating CD4 T-Cell Differentiation.

Diabetes predisposition inherited through maternal germline.

Preimplantation genetic testing for aneuploidy in severe male factor infertility: protocol for a multicenter randomised controlled trial.

Associations Between Asthma and Polycystic Ovary Syndrome: Current Perspectives.

Lysophosphatidic Acid Improves Human Sperm Motility by Enhancing Glycolysis and Activating L-Type Calcium Channels.

Tracking of menstrual cycles and prediction of the fertile window via measurements of basal body temperature and heart rate as well as machine-learning algorithms.

Effect of Maternal Glucose and Triglyceride Levels during Early Pregnancy on Pregnancy Outcomes: A Retrospective Cohort Study.

Interactive effects of ambient air pollution and sunshine duration on the risk of intrahepatic cholestasis of pregnancy.

Internet-based cognitive therapy for women with antenatal depressive symptoms during the COVID-19 pandemic: protocol for a multi-center randomized controlled trial across China.

Living birth following preimplantation genetic testing for monogenic disorders to prevent low-level germline mosaicism related Nicolaides-Baraitser syndrome.

LncRNA THOR promotes endometrial cancer progression through the AKT and ERK signaling pathways.

Maternal lipid profile during early pregnancy and birth weight: A retrospective study.

Genetic deconvolution of fetal and maternal cell-free DNA in maternal plasma enables next-generation non-invasive prenatal screening.

Editorial: Polycystic ovary syndrome (PCOS): Mechanism and management.

Breastfeeding Practices and Associated Factors in Shanghai: A Cross-Sectional Study.

The lncRNA THOR interacts with and stabilizes hnRNPD to promote cell proliferation and metastasis in breast cancer.

Construction of a ceRNA network in polycystic ovary syndrome (PCOS) driven by exosomal lncRNA.

Associations between short-term and long-term exposure to particulate matter and preterm birth.

Association of maternal triglyceride responses to thyroid function in early pregnancy with gestational diabetes mellitus.

Small RNA perspective of physical exercise-related improvement of male reproductive dysfunction due to obesity.

The epigenetic mechanisms underlying gamete origin of adult-onset diseases.

Effects of parental overweight and obesity on offspring's mental health: A meta-analysis of observational studies.

A PPARG Splice Variant in Granulosa Cells Is Associated with Polycystic Ovary Syndrome.

Association between Plasma Trace Element Concentrations in Early Pregnancy and Gestational Diabetes Mellitus in Shanghai, China.

Parental mosaicism detection and preimplantation genetic testing in families with multiple transmissions of de novo mutations.

Characteristics and possible mechanisms of metabolic disorder in overweight women with polycystic ovary syndrome.

Delivery and neonatal outcomes of pregnant women during the Shanghai lockdown: A retrospective analysis.

Preimplantation Genetic Testing (PGT) and Prenatal Diagnosis of Schaaf-Yang Syndrome: A Report of Three Families and a Research on Genotype-Phenotype Correlations.

Comparative effectiveness of transvaginal repair vs. hysteroscopic resection in patients with symptomatic uterine niche.

An intergenerational life-course approach to address early childhood obesity and adiposity: the Healthy Life Trajectories Initiative (HeLTI).

Serum anti-Müllerian hormone levels are associated with perinatal outcomes in women undergoing IVF/ICSI: A multicenter retrospective cohort study.

Effects of Particulate Matter on the Risk of Gestational Hypertensive Disorders and Their Progression.

Effect of Frozen-Thawed Embryo Transfer on the Metabolism of Children in Early Childhood.

Mixed exposure effect of seminal metals on semen quality, mediation of total antioxidant capacity, and moderation of GSTM1/GSTT1 gene deletion in Chinese reproductive-aged men.

The causal association between smoking initiation, alcohol and coffee consumption, and women's reproductive health: A two-sample Mendelian randomization analysis.

Sperm morphological abnormalities in autosomal dominant polycystic kidney disease are associated with the Hippo signaling pathway via PC1.

Developmental origins of diabetes mellitus: Environmental epigenomics and emerging patterns.

Biallelic variants in RBM42 cause a multisystem disorder with neurological, facial, cardiac, and musculoskeletal involvement.

The Influences of Perinatal Androgenic Exposure on Cardiovascular and Metabolic Disease of Offspring of PCOS.

Machine learning and bioinformatics framework integration reveal potential characteristic genes related to immune cell infiltration in preeclampsia.

Elevated follicular cortisone level is a negative predictor of clinical pregnancy in women undergoing fresh embryo transfer.

Carrier burden of over 300 diseases in Han Chinese identified by expanded carrier testing of 300 couples using assisted reproductive technology.

Fetal weight estimation based on deep neural network: a retrospective observational study.

Research Progress of Maternal Metabolism on Cardiac Development and Function in Offspring.

Rare loss-of-function variants reveal threshold and multifactorial inheritance of dextrocardia.

Editorial: Polycystic ovary syndrome: mechanism and management-volume II.

Noninvasive Evaluation of Fetal Zygosity in Twin Pregnancies Involving a Binary Analysis of Single-Nucleotide Polymorphisms.

Overexpression of Pde4d in rat granulosa cells inhibits maturation and atresia of antral follicles to induce polycystic ovary.

Developmental origins of adult diseases.

Recurrent human 16p11.2 microdeletions in type I Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome patients in Chinese Han population.

NLRP3 Inflammasome-dependent Pathway is Involved in the Pathogenesis of Polycystic Ovary Syndrome.

Early characterisation and prediction of liver diseases in pregnancy by plasma cell-free RNAs.

Follicle-stimulating hormone orchestrates glucose-stimulated insulin secretion of pancreatic islets.

Assisted reproductive technology and imprinting errors: analyzing underlying mechanisms from epigenetic regulation.

Polycystic Ovary Syndrome Fuels Cardiovascular Inflammation and Aggravates Ischemic Cardiac Injury.

Chinese experts' consensus guideline on preimplantation genetic testing of monogenic disorders.

Research Progress on the effects of adverse exposure during pregnancy on skeletal muscle function in offspring.

Research progress and challenges of preimplantation genetic testing for polygenic diseases.

Prediction of shared gene signatures and biological mechanisms between polycystic ovary syndrome and asthma: Based on weighted gene coexpression network analysis.

Metabolome implies increased fatty acid utilization and histone methylation in the follicles from hyperandrogenic PCOS women.

Sexual behavior and cardiovascular diseases: univariable and multivariable Mendelian randomization.

Effect of transvaginal Lactobacillus supplementation on reversing lower genital tract dysbiosis and improving perinatal outcomes in PCOS patients after IVF-FET: a study protocol for a multicenter randomized controlled trial.

Long-term health risk of offspring born from assisted reproductive technologies.

Prospective prenatal cell-free DNA screening for genetic conditions of heterogenous etiologies.

Cardiovascular health of offspring conceived by assisted reproduction technology: a comprehensive review.

LncRNA SNHG5 adversely governs follicular growth in PCOS via miR-92a-3p/CDKN1C axis.

Practice guideline on ovarian tissue cryopreservation and transplantation in the prevention and treatment of iatrogenic premature ovarian insufficiency.

A mutual comparison of pregnancy outcomes between different conception modes: a propensity score matching based retrospective cohort study.

A morphological study of symptomatic uterine niche using three-dimensional models from thin-slice magnetic resonance imaging.

Association of serum folic acid levels in response to fasting blood glucose in early pregnancy with the risk of gestational diabetes mellitus: A retrospective cohort study.

A novel preimplantation genetic testing strategy for a subtelomeric genetic disorder: A case study.

Sex-Specific Alterations in Placental Proteomics Induced by Intrauterine Hyperglycemia.

Reduction in Placental Metal and Metalloid in Preeclampsia: A Case-Control Study.

The impact of maternal age on aneuploidy in oocytes: Reproductive consequences, molecular mechanisms, and future directions.

FSH regulates glucose-stimulated insulin secretion: A bell-shaped curve effect.

Pre-eclamptic foetal programming predisposes offspring to hepatic steatosis via DNA methylation.

Characterization of a novel adipose tissue located between abdominal lymph nodes and cervix/prostate in mice.

Intrauterine hyperglycemia induces SIRT3-mediated mitochondrial dysfunction: the fetal origin pathogenesis of precocious osteoarthritis.

Cerium Oxide Nanozymes Improve Skeletal Muscle Function in Gestational Diabetic Offspring by Attenuating Mitochondrial Oxidative Stress.

Deamidation enables pathogenic SMAD6 variants to activate the BMP signaling pathway.

Effects of exposure to multiple metallic elements in the first trimester of pregnancy on the risk of preterm birth.

[Reproductive Health-Oriented Development in Assisted Reproductive Technologies].