Department of Cellular and Molecular Medicine,
Laboratory of Molecular and Cellular Signaling,
Department of Cellular and Molecular Medicine, Laboratory of Molecular and Cellular Signaling
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The role of calmodulin for inositol 1,4,5-trisphosphate receptor function.
Biochimica et biophysica acta Nov, 2002 | Pubmed ID: 12445455
Regulation of InsP3 receptor activity by neuronal Ca2+-binding proteins.
The EMBO journal Jan, 2004 | Pubmed ID: 14685260
The 12 kDa FK506-binding protein, FKBP12, modulates the Ca(2+)-flux properties of the type-3 ryanodine receptor.
Journal of cell science Mar, 2004 | Pubmed ID: 14970260
Thimerosal stimulates Ca2+ flux through inositol 1,4,5-trisphosphate receptor type 1, but not type 3, via modulation of an isoform-specific Ca2+-dependent intramolecular interaction.
The Biochemical journal Jul, 2004 | Pubmed ID: 15015936
The N-terminal Ca2+-independent calmodulin-binding site on the inositol 1,4,5-trisphosphate receptor is responsible for calmodulin inhibition, even though this inhibition requires Ca2+.
Molecular pharmacology Aug, 2004 | Pubmed ID: 15266018
Caspase-3-induced truncation of type 1 inositol trisphosphate receptor accelerates apoptotic cell death and induces inositol trisphosphate-independent calcium release during apoptosis.
The Journal of biological chemistry Oct, 2004 | Pubmed ID: 15284241
Suramin and disulfonated stilbene derivatives stimulate the Ca2+-induced Ca2+ -release mechanism in A7r5 cells.
Molecular pharmacology Jul, 2005 | Pubmed ID: 15851651
The protein phosphatase 2A phosphatase activator is a novel peptidyl-prolyl cis/trans-isomerase.
The Journal of biological chemistry Mar, 2006 | Pubmed ID: 16380387
The suppressor domain of inositol 1,4,5-trisphosphate receptor plays an essential role in the protection against apoptosis.
Cell calcium Apr, 2006 | Pubmed ID: 16458354
Slm1 and slm2 are novel substrates of the calcineurin phosphatase required for heat stress-induced endocytosis of the yeast uracil permease.
Molecular and cellular biology Jun, 2006 | Pubmed ID: 16738335
Synthesis and biological action of novel 4-position-modified derivatives of D-myo-inositol 1,4,5-trisphosphate.
The Journal of organic chemistry Jul, 2007 | Pubmed ID: 17585817
The tumor suppressor eIF3e mediates calcium-dependent internalization of the L-type calcium channel CaV1.2.
Neuron Aug, 2007 | Pubmed ID: 17698014
Caspase-3-truncated type 1 inositol 1,4,5-trisphosphate receptor enhances intracellular Ca2+ leak and disturbs Ca2+ signalling.
Biology of the cell / under the auspices of the European Cell Biology Organization Jan, 2008 | Pubmed ID: 17868032
The myosin II ATPase inhibitor blebbistatin prevents thrombin-induced inhibition of intercellular calcium wave propagation in corneal endothelial cells.
Investigative ophthalmology & visual science Nov, 2008 | Pubmed ID: 18614806
Targeting Bcl-2-IP3 receptor interaction to reverse Bcl-2's inhibition of apoptotic calcium signals.
Molecular cell Jul, 2008 | Pubmed ID: 18657507
Regulation of inositol 1,4,5-trisphosphate-induced Ca2+ release by reversible phosphorylation and dephosphorylation.
Biochimica et biophysica acta Jun, 2009 | Pubmed ID: 19133301
Regioselective deprotection of orthobenzoates for the synthesis of inositol phosphates.
Organic & biomolecular chemistry Apr, 2009 | Pubmed ID: 19343261
Regulation of inositol 1,4,5-trisphosphate receptor type 1 function during oocyte maturation by MPM-2 phosphorylation.
Cell calcium Jul, 2009 | Pubmed ID: 19482353
Pannexins, distant relatives of the connexin family with specific cellular functions?
BioEssays : news and reviews in molecular, cellular and developmental biology Sep, 2009 | Pubmed ID: 19644918
The BH4 domain of Bcl-2 inhibits ER calcium release and apoptosis by binding the regulatory and coupling domain of the IP3 receptor.
Proceedings of the National Academy of Sciences of the United States of America Aug, 2009 | Pubmed ID: 19706527
Intracellular Ca2+ storage in health and disease: a dynamic equilibrium.
Cell calcium Apr, 2010 | Pubmed ID: 20189643
Polycystin-2 activation by inositol 1,4,5-trisphosphate-induced Ca2+ release requires its direct association with the inositol 1,4,5-trisphosphate receptor in a signaling microdomain.
The Journal of biological chemistry Jun, 2010 | Pubmed ID: 20375013
Intramolecular loop/tail interactions are essential for connexin 43-hemichannel activity.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology Nov, 2010 | Pubmed ID: 20634352
Pannexin channels in ATP release and beyond: an unexpected rendezvous at the endoplasmic reticulum.
Cellular signalling Feb, 2011 | Pubmed ID: 20688156
Connexins: sensors and regulators of cell cycling.
Biochimica et biophysica acta Jan, 2011 | Pubmed ID: 20801193
STIM1, but not STIM2, is required for proper agonist-induced Ca2+ signaling.
Cell calcium Aug-Sep, 2010 | Pubmed ID: 20801505
Development of inositol-based antagonists for the D-myo-inositol 1,4,5-trisphosphate receptor.
Chemical communications (Cambridge, England) Jan, 2011 | Pubmed ID: 20938532
The IP(3) receptor-mitochondria connection in apoptosis and autophagy.
Biochimica et biophysica acta May, 2011 | Pubmed ID: 21146562
Induction of Ca²+-driven apoptosis in chronic lymphocytic leukemia cells by peptide-mediated disruption of Bcl-2-IP3 receptor interaction.
Blood Mar, 2011 | Pubmed ID: 21193695
Unraveling the role of polycystin-2/inositol 1,4,5-trisphosphate receptor interaction in Ca signaling.
Communicative & integrative biology Nov, 2010 | Pubmed ID: 21331231
IP(3) Receptors, Mitochondria, and Ca Signaling: Implications for Aging.
Journal of aging research , 2011 | Pubmed ID: 21423550
Endoplasmic-reticulum calcium depletion and disease.
Cold Spring Harbor perspectives in biology Jun, 2011 | Pubmed ID: 21441595
A dual role for Ca(2+) in autophagy regulation.
Cell calcium Sep, 2011 | Pubmed ID: 21571367
Calcium and connexin-based intercellular communication, a deadly catch?
Cell calcium Sep, 2011 | Pubmed ID: 21621840
Connexin channels provide a target to manipulate brain endothelial calcium dynamics and blood-brain barrier permeability.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism Sep, 2011 | Pubmed ID: 21654699
Non-channel functions of connexins in cell growth and cell death.
Biochimica et biophysica acta Aug, 2012 | Pubmed ID: 21718687
STIM1 as a key regulator for Ca2+ homeostasis in skeletal-muscle development and function.
Skeletal muscle , 2011 | Pubmed ID: 21798093
Ins(1,4,5)P3 receptor-mediated Ca2+ signaling and autophagy induction are interrelated.
Autophagy Dec, 2011 | Pubmed ID: 22082873
The C terminus of Bax inhibitor-1 forms a Ca2+-permeable channel pore.
The Journal of biological chemistry Jan, 2012 | Pubmed ID: 22128171
Connexin 43 hemichannels contribute to cytoplasmic Ca2+ oscillations by providing a bimodal Ca2+-dependent Ca2+ entry pathway.
The Journal of biological chemistry Apr, 2012 | Pubmed ID: 22351781
The contractile system as a negative regulator of the connexin 43 hemichannel.
Biology of the cell / under the auspices of the European Cell Biology Organization Jul, 2012 | Pubmed ID: 22375941
Release of gliotransmitters through astroglial connexin 43 hemichannels is necessary for fear memory consolidation in the basolateral amygdala.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology Sep, 2012 | Pubmed ID: 22665389
Role of the inositol 1,4,5-trisphosphate receptor/Ca2+-release channel in autophagy.
Cell communication and signaling : CCS , 2012 | Pubmed ID: 22770472
Low extracellular Ca2+ conditions induce an increase in brain endothelial permeability that involves intercellular Ca2+ waves.
Brain research Dec, 2012 | Pubmed ID: 22789903
Paracrine signaling through plasma membrane hemichannels.
Biochimica et biophysica acta Jan, 2013 | Pubmed ID: 22796188
RhoA GTPase switch controls Cx43-hemichannel activity through the contractile system.
PloS one , 2012 | Pubmed ID: 22860057
Manipulating connexin communication channels: use of peptidomimetics and the translational outputs.
The Journal of membrane biology Aug, 2012 | Pubmed ID: 22886208
The selective BH4-domain biology of Bcl-2-family members: IP3Rs and beyond.
Cellular and molecular life sciences : CMLS Apr, 2013 | Pubmed ID: 22955373
Guidelines for the use and interpretation of assays for monitoring autophagy.
Autophagy Apr, 2012 | Pubmed ID: 22966490
Profiling of the Bcl-2/Bcl-X(L)-binding sites on type 1 IP(3) receptor.
Biochemical and biophysical research communications Nov, 2012 | Pubmed ID: 23058917
Neuronal overexpression of IP₃ receptor 2 is detrimental in mutant SOD1 mice.
Biochemical and biophysical research communications Dec, 2012 | Pubmed ID: 23131553
Selective inhibition of Cx43 hemichannels by Gap19 and its impact on myocardial ischemia/reperfusion injury.
Basic research in cardiology Jan, 2013 | Pubmed ID: 23184389
Altered Ca(2+) signaling in cancer cells: proto-oncogenes and tumor suppressors targeting IP3 receptors.
Biochimica et biophysica acta Apr, 2013 | Pubmed ID: 23232185
IP3, a small molecule with a powerful message.
Biochimica et biophysica acta Jul, 2013 | Pubmed ID: 23291251
Negatively charged residues (Asp378 and Asp379) in the last ten amino acids of the C-terminal tail of Cx43 hemichannels are essential for loop/tail interactions.
Biochemical and biophysical research communications Mar, 2013 | Pubmed ID: 23376080
Regulation of inositol 1,4,5-trisphosphate receptors during endoplasmic reticulum stress.
Biochimica et biophysica acta Jul, 2013 | Pubmed ID: 23380704
HA14-1, but not the BH3 mimetic ABT-737, causes Ca2+ dysregulation in platelets and human cell lines.
Haematologica Apr, 2013 | Pubmed ID: 23403318
mTOR-Controlled Autophagy Requires Intracellular Ca(2+) Signaling.
PloS one , 2013 | Pubmed ID: 23565295
Curcumin affects proprotein convertase activity: Elucidation of the molecular and subcellular mechanism.
Biochimica et biophysica acta Aug, 2013 | Pubmed ID: 23583304
Peptides and peptide-derived molecules targeting the intracellular domains of Cx43: Gap junctions versus hemichannels.
Neuropharmacology May, 2013 | Pubmed ID: 23664811
Regulation of connexin- and pannexin-based channels by post-translational modifications.
Biology of the cell / under the auspices of the European Cell Biology Organization May, 2013 | Pubmed ID: 23718186
Endothelial calcium dynamics; connexin channels and blood brain barrier function.
Progress in neurobiology Jul, 2013 | Pubmed ID: 23851106
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