Physiology and Biophyics,
Department of Physiology and Biophysics
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GDNF availability determines enteric neuron number by controlling precursor proliferation.
Development (Cambridge, England) May, 2003 | Pubmed ID: 12668632
Differential signalling by muscarinic receptors in smooth muscle: m2-mediated inactivation of myosin light chain kinase via Gi3, Cdc42/Rac1 and p21-activated kinase 1 pathway, and m3-mediated MLC20 (20 kDa regulatory light chain of myosin II) phosphorylation via Rho-associated kinase/myosin phosphatase targeting subunit 1 and protein kinase C/CPI-17 pathway.
The Biochemical journal Aug, 2003 | Pubmed ID: 12733988
Inhibition of sustained smooth muscle contraction by PKA and PKG preferentially mediated by phosphorylation of RhoA.
American journal of physiology. Gastrointestinal and liver physiology Jun, 2003 | Pubmed ID: 12736149
Physiological role of neuropeptide Y in the regulation of the ascending phase of the peristaltic reflex.
American journal of physiology. Gastrointestinal and liver physiology Dec, 2003 | Pubmed ID: 12919938
Neurotransmitters mediating the intestinal peristaltic reflex in the mouse.
The Journal of pharmacology and experimental therapeutics Nov, 2003 | Pubmed ID: 12966154
Gastrin-releasing peptide is a modulatory neurotransmitter of the descending phase of the peristaltic reflex.
American journal of physiology. Gastrointestinal and liver physiology Dec, 2004 | Pubmed ID: 15297260
Coexpression of Y1, Y2, and Y4 receptors in smooth muscle coupled to distinct signaling pathways.
The Journal of pharmacology and experimental therapeutics Dec, 2004 | Pubmed ID: 15308651
Gq/G13 signaling by ET-1 in smooth muscle: MYPT1 phosphorylation via ETA and CPI-17 dephosphorylation via ETB.
American journal of physiology. Cell physiology Nov, 2004 | Pubmed ID: 15475516
Differential expression of Y receptors and signaling pathways in intestinal circular and longitudinal smooth muscle.
Regulatory peptides Feb, 2005 | Pubmed ID: 15582728
Desensitization of the peristaltic reflex induced by mucosal stimulation with the selective 5-HT4 agonist tegaserod.
American journal of physiology. Gastrointestinal and liver physiology Feb, 2006 | Pubmed ID: 16223945
Brain-derived neurotrophic factor augments peristalsis by augmenting 5-HT and calcitonin gene-related peptide release.
Gastroenterology Mar, 2006 | Pubmed ID: 16530518
Cross-regulation of VPAC(2) receptor desensitization by M(3) receptors via PKC-mediated phosphorylation of RKIP and inhibition of GRK2.
American journal of physiology. Gastrointestinal and liver physiology Mar, 2007 | Pubmed ID: 17170028
Up-regulation of calcitonin gene-related peptide and receptor tyrosine kinase TrkB in rat bladder afferent neurons following TNBS colitis.
Experimental neurology Apr, 2007 | Pubmed ID: 17303123
Autoinhibition of endothelial nitric oxide synthase (eNOS) in gut smooth muscle by nitric oxide.
Regulatory peptides Nov, 2008 | Pubmed ID: 18926858
Alterations to enteric neural signaling underlie secretory abnormalities of the ileum in experimental colitis in the guinea pig.
American journal of physiology. Gastrointestinal and liver physiology Apr, 2009 | Pubmed ID: 19221017
Endogenous IGF-I and alpha v beta3 integrin ligands regulate increased smooth muscle growth in TNBS-induced colitis.
American journal of physiology. Gastrointestinal and liver physiology Jun, 2009 | Pubmed ID: 19359426
Colitis induces calcitonin gene-related peptide expression and Akt activation in rat primary afferent pathways.
Experimental neurology Sep, 2009 | Pubmed ID: 19422825
Modulation of motor and sensory pathways of the peristaltic reflex by cannabinoids.
American journal of physiology. Gastrointestinal and liver physiology Sep, 2009 | Pubmed ID: 19589944
Endogenous IGF-I and alphaVbeta3 integrin ligands regulate increased smooth muscle hyperplasia in stricturing Crohn's disease.
Gastroenterology Jan, 2010 | Pubmed ID: 19751734
The timing and location of glial cell line-derived neurotrophic factor expression determine enteric nervous system structure and function.
The Journal of neuroscience : the official journal of the Society for Neuroscience Jan, 2010 | Pubmed ID: 20107080
Colitis elicits differential changes in the expression levels of receptor tyrosine kinase TrkA and TrkB in colonic afferent neurons: a possible involvement of axonal transport.
Pain Oct, 2010 | Pubmed ID: 20638179
Amelioration of excess collagen IαI, fibrosis, and smooth muscle growth in TNBS-induced colitis in IGF-I(+/-) mice.
Inflammatory bowel diseases Mar, 2011 | Pubmed ID: 20722057
Endogenous IGFBP-3 regulates excess collagen expression in intestinal smooth muscle cells of Crohn's disease strictures.
Inflammatory bowel diseases Jan, 2011 | Pubmed ID: 20848532
Inhibition of monoacylglycerol lipase attenuates nonsteroidal anti-inflammatory drug-induced gastric hemorrhages in mice.
The Journal of pharmacology and experimental therapeutics Sep, 2011 | Pubmed ID: 21659471
Up-regulation of brain-derived neurotrophic factor in primary afferent pathway regulates colon-to-bladder cross-sensitization in rat.
Journal of neuroinflammation , 2012 | Pubmed ID: 22335898
Up-regulation of brain-derived neurotrophic factor is regulated by extracellular signal-regulated protein kinase 5 and by nerve growth factor retrograde signaling in colonic afferent neurons in colitis.
Experimental neurology Dec, 2012 | Pubmed ID: 22921460
Activation of transmembrane bile acid receptor TGR5 stimulates insulin secretion in pancreatic β cells.
Biochemical and biophysical research communications Oct, 2012 | Pubmed ID: 23022524
Morphine decreases enteric neuron excitability via inhibition of sodium channels.
PloS one , 2012 | Pubmed ID: 23028881
The receptor TGR5 mediates the prokinetic actions of intestinal bile acids and is required for normal defecation in mice.
Gastroenterology Jan, 2013 | Pubmed ID: 23041323
Activation of G protein-coupled bile acid receptor, TGR5, induces smooth muscle relaxation via both Epac- and PKA-mediated inhibition of RhoA/Rho kinase pathway.
American journal of physiology. Gastrointestinal and liver physiology Mar, 2013 | Pubmed ID: 23275618
Electrophysiological characteristics of enteric neurons isolated from the immortomouse.
Digestive diseases and sciences Jun, 2013 | Pubmed ID: 23371009
Caveolae-dependent internalization and homologous desensitization of VIP/PACAP receptor, VPACâ‚‚, in gastrointestinal smooth muscle.
Peptides May, 2013 | Pubmed ID: 23499767
Characterization of signaling pathways coupled to melatonin receptors in gastrointestinal smooth muscle.
Regulatory peptides Jun, 2013 | Pubmed ID: 23541890
TRPM5-dependent amiloride- and benzamil-insensitive NaCl chorda tympani taste nerve response.
American journal of physiology. Gastrointestinal and liver physiology Jul, 2013 | Pubmed ID: 23639808
Differential Expression of Multidrug-Resistance Protein 5 and Phosphodiesterase 5 and Regulation of cGMP Levels in Phasic and Tonic Smooth Muscle.
American journal of physiology. Gastrointestinal and liver physiology Jun, 2013 | Pubmed ID: 23764893
Differential regulation of muscarinic M2 and M3 receptor signaling in gastrointestinal smooth muscle by caveolin-1.
American journal of physiology. Cell physiology Aug, 2013 | Pubmed ID: 23784544
Changes in the Expression of Smooth Muscle Contractile Proteins in TNBS- and DSS-Induced Colitis in Mice.
Inflammation Jun, 2013 | Pubmed ID: 23794034
Retinaldehyde dehydrogenase enzymes regulate colon enteric nervous system structure and function.
Developmental biology Jun, 2013 | Pubmed ID: 23806210
Distinctive G Protein-Dependent Signaling by Protease-Activated Receptor 2 (PAR2) in Smooth Muscle: Feedback Inhibition of RhoA by cAMP-Independent PKA.
PloS one , 2013 | Pubmed ID: 23825105
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